Research Scientist, Medicinal Chemistry
4 days ago
Bicycle Therapeutics is a clinical-stage biopharmaceutical company seeking a highly skilled Research Scientist to join our dynamic and fast-moving team.
Key Responsibilities- Support chemistry activities within a project team, including the design of bioactive Bicycle peptides to a set Target Product Profile.
- Serve on internal project teams, communicate with project team and colleagues effectively and work well with others to meet experimental and organizational goals.
- Present the results of research activities effectively in oral or written form to line manager, project team members and management level meetings.
- Coordinate chemistry at external contract research organizations (CROs) including maintaining a good relationship, development of chemistry plans, project tracking, data and compound management, evaluation of results and analytical data including NMR, LCMS, HPLC, UV-VIS and troubleshooting synthetic issues.
- Prepare reports and contribute to drafting patent filings and journal manuscripts.
- Support the development of new innovations which expand the company platform.
- Relevant industry or academic experience in contemporary medicinal chemistry and in the design and synthesis of bioactive peptides and conjugates in preclinical drug discovery programs.
- Experience in interpreting SAR data desirable (activity, selectivity, DMPK characteristics, physical properties etc.).
- Demonstrated experience in managing external (CRO, CMO) resources to accomplish project tasks.
- Excellent organizational skills and ability to work independently, flexibly and reliably, prioritizing accordingly to the company objectives.
- Team player who collaborates and communicates effectively in team environment. Comfortable sharing knowledge with wider company team and, as appropriate, report work to the scientific or industry community.
- Innovative, entrepreneurial, enjoys working in a fast-paced environment.
- Experience in peptide chemistry research.
- Experience in developing drug conjugates or radiopharmaceuticals.
- Use of structure based drug design and the use of computational modelling and data analysis software to support drug development activities.
Bicycle Therapeutics offers a state-of-the-art campus environment with on-campus restaurant and Montessori nursery. We provide flexible working environment, competitive rewards, employee recognition schemes, and a range of benefits including annual leave, pension contribution, life assurance cover, private medical insurance, group income protection, employee assistance program, health cash plan, access to company subsidized gym membership, and eligibility for an option grant to subscribe to shares in Bicycle Therapeutics plc.
Our Commitment to Diversity and InclusionBicycle Therapeutics is committed to building a diverse workforce that is representative of the communities we serve. We recognize that diverse and inclusive teams build a stronger and more innovative company. Therefore, all qualified applicants will be considered for employment, and we do not discriminate on the basis of race, religion, colour, gender, sexual orientation, age, disability status, marital status, or veteran status.
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Cambridge, Cambridgeshire, United Kingdom Bicycle Therapeutics Full timeJob SummaryWe are seeking a highly skilled Research Scientist to join our dynamic Medicinal Chemistry team at Bicycle Therapeutics. As a key member of our team, you will be responsible for designing and synthesizing novel Bicycles and conjugates to develop lead candidates for our oncology pipeline.Key ResponsibilitiesDesign and synthesis of novel Bicycles...
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Cambridge, Cambridgeshire, United Kingdom Bicycle Therapeutics Full timeJob SummaryWe are seeking a highly skilled Research Scientist to join our dynamic Medicinal Chemistry team at Bicycle Therapeutics. As a key member of our team, you will be responsible for designing and synthesizing novel Bicycles and conjugates to develop lead candidates.Key ResponsibilitiesManage external resources to deliver on synthetic and analytical...
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