Research Assistant/associate
3 weeks ago
**Salary**:
**Research Assistant**: £31,396 to £32,982 per annum
**Research Associate**: £33,966 to £44,263 per annum
Newcastle University is a great place to work, with excellent benefits. We have a generous holiday package; plus the opportunity to buy more, great pension schemes and a number of health and wellbeing initiatives to support you.
**Closing Date**: 08 September 2023
The Role
This is a Research Assistant/Associate position, as part of a programme of work funded by Cancer Research UK to investigate the biology of neutrophils in the hepatocellular carcinoma (HCC) tumour microenvironment. The project will use a variety of approaches including multi-omics, high performance imaging and experimental modelling (in vitro and in vivo) to determine phenotypes and functions of neutrophils in HCC tumours from clinical and experimental sources. You will work in the internationally renowned Newcastle Fibrosis Research Group under the supervision of Prof Derek Mann and Dr Jack Leslie, and in close collaboration with colleagues based at the CRUK Beatson Institute at Glasgow. The aim of the programme is to advance recent work from the team describing approaches by which tumour neutrophils can be therapeutically manipulated to enhance immunotherapy. The post would be ideally suited to a PhD cell biologist or immunologist with previous experience working with complex experimental models of solid tumours.
Find out more about the Faculty of Medical Sciences here.
Find out more about our Research Institutes here.
As part of our commitment to career development for research colleagues, the University has developed 3 levels of research role profiles. These profiles set out firstly the generic competences and responsibilities expected of role holders at each level and secondly the general qualifications and experiences needed for entry at a particular level.
Key Accountabilities
- You will have a strong interest in developing a career in cancer immunology and will preferably be able to demonstrate previous hands-on experience in cell culture, molecular immunology, experimental modelling of disease, singe cell transcriptomics, spatial transcriptomics, flow cytometry or imaging
- To facilitate the fibrosis group in other aspects of its operation including contribution to laboratory meetings, contribution to web-based activities and contribution to its public engagement activities
- To facilitate general management and running of the laboratory including routine laboratory cleaning, maintenance, equipment upkeep and ordering of laboratory materials
- Analyse data statistically and have a major input into both the experimental design and methodology
- Manage your time effectively and work independently on a day-to-day basis, but also work closely with Project supervisors and other members of the research team
- Attend research seminars and other departmental meetings as required. Contribute to the presentation of results to the group and to the research community in general
- Ensure that all work done in the laboratory complies with the applicable regulations concerning biohazards and radiation
- Arrange equipment maintenance and repair, as necessary
- Contribute to the preparation of reports and scientific publications, as requested by project coordinators
- Comply with University policies, including financial regulations, equal opportunities policy, health and safety policy, promoting race equality policy, information systems security policy, data security and intellectual property rights
- Carry out any other duties, which may arise commensurate with the grade of the post, as requested by the project coordinators
- Liaise with suppliers and manufacturers to resolve problems and investigate replacement options
- By developing local procedures, establish and maintain a safe/compliant working environment
- Assist with the completion and updating of a wide range of safety paperwork
- Complete accident reporting
- Schedule, prioritize and monitor work and performance in line with demands and deadlines
- Hold delegated responsibility from the academic/technical lead for the planning, operation, and supervision of a variety of laboratory spaces
- Organize and facilitate progress and management meetings
- Oversee local record keeping, inventory and asset management
- Monitor resource usage and stores operations
- Source and negotiate with suppliers for a range of items including specialist parts/equipment
- Create, update and implement procedures to deliver an aligned, efficient and effective service
- Design, develop and deliver inductions, demonstrations and training covering a broad range of activities (not limited to techniques and equipment)
- Develop a broad knowledge and skills base, sharing with others
- Mentor junior staff
- Any other duties within the scope and general nature of the grade which may be required
The Person (Essential)
Knowledge, Skills and Experience
- Hands-on experience with in vivo mod
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