Research Assistant/associate

3 weeks ago

Newcastle upon Tyne, United Kingdom Newcastle University Full time

We are a world class research-intensive university. We deliver teaching and learning of the highest quality. We play a leading role in economic, social and cultural development of the North East of England. Attracting and retaining high-calibre people is fundamental to our continued success.

What’s in it for you? Newcastle University is a great place to work, with excellent benefits. We have a generous holiday package; plus the opportunity to buy more, great pension schemes and a number of health and wellbeing initiatives to support you.

Newcastle is an inclusive global University community where everyone is treated with dignity and respect. As a University of Sanctuary, we aim to provide a welcoming place of safety for all, offering opportunities to people fleeing violence and persecution.

Salary

**Research Assistant**: £29,619 to £31,411 per annum

**Research Associate**: £32,348 to £35,333 per annum

**Closing Date**: 20 January 2023

The Role

We are looking to recruit an enthusiastic and highly motivated post-doctoral Research Associate in the laboratory of Professor Tracy Palmer. The project will focus on toxin substrates of the Staphylococcus aureus Type VII protein secretion system and how they are recognised by the secretion machinery. You will identify interacting partners of toxin substrates and characterise complexes using structural biology and biochemistry. You will construct mutant strains of S. aureus to determine roles of partners in targeting and secretion. You will define interactions of toxins and partners with the secretion machinery.

You must have experience of working with Staphylococcus aureus including construction of mutant strains and handling S. aureus membrane proteins, and of structural biology approaches.

Find out more about the Faculty of Medical Sciences here.
Find out more about our Research Institutes here.

As part of our commitment to career development for research colleagues, the University has developed 3 levels of research role profiles. These profiles set out firstly the generic competences and responsibilities expected of role holders at each level and secondly the general qualifications and experiences needed for entry at a particular level.

Key Accountabilities
- Although working under the general guidance of an academic or Principal Investigator, the postholder will contribute ideas, including enhancements to the technical or methodological aspects of their studies, thus providing substantial 'added value'
- Develop and carry out the specified project using appropriate techniques and equipment as outlined in the personal requirements
- Determine appropriate methodologies for research, with advice and support where required
- Assess research findings for the need/scope for further investigations
- Contribute to the writing up of their research for publication and dissemination, either through seminar and conference presentations or through publications
- Present research findings, either at conferences or through publications in reputable outlets appropriate to the discipline
- May be involved in the supervision, with guidance, of final year undergraduate research projects and masters projects, and in providing support to postgraduate research students or Research Assistants
- Will need to work with the support staff and, on occasions, with undergraduate and postgraduate students, and interact intellectually with other academic members of the Institute.
- May contribute to events celebrating the public engagement of science/social sciences/humanities
- Develop an awareness of University structures, policies and procedures and relevant issues in the higher education, research, social and political environment

The Person

Knowledge, Skills and Experience
- Ability to work well as part of a team and rapidly acquire new skills
- Likelihood of advanced skills directly related to the research projects
- High level of analytical and problem-solving capability
- Ability to communicate complex information with clarity and to encourage the commitment of others
- Experience of research with clear transferable skills and some experience or awareness of the research environment
- Presentations at conferences and/or high-quality publications
- Experience constructing chromosomal mutations of S. aureus
- Experience with handling S. aureus membrane proteins
- Structural biology experience
- Molecular biology experience including site-directed mutagenesis

Desirable
- Experience with the zebrafish virulence model

**Qualifications**:

- The postholder should have a PhD in microbiology/biochemistry or a related discipline (Research Associate)

The University holds a silver Athena SWAN award in recognition of our good employment practices for the advancement of gender equality. The University is also a member of the Euraxess initiative supporting researchers in Europe.

**Requisition ID**: 24940

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