PhD Researcher: Glycosaminoglycan Mapping in Breast Cancer

4 weeks ago


Nottingham, Nottingham, United Kingdom University of Nottingham Full time

Project Overview:

The University of Nottingham is seeking a highly motivated PhD researcher to join an extensive team of scientists delivering a BBSRC strategic Longer and Larger project. The project aims to isolate a range of recombinant antibodies that bind to glycosaminoglycans (GAGs), producing highly specific probes. The researcher will use the latest developments in antibody phage display technology, coupling the binding of vast antibody-phage libraries with the screening power of next generation sequencing (NGPD).

Research Objectives:

  • Isolate recombinant antibodies that bind to GAGs
  • Develop highly specific probes for GAG detection and characterization
  • Apply NGPD to target cell surface GAGs from breast cancer cell populations
  • Characterize binding against breast cancer cell populations and defined GAG structures

Requirements:

  • Minimum of a 2.1 undergraduate biological science degree or a minimum of a 2.2 degree and a Master's degree in a related subject
  • Strong background in molecular biology, biochemistry, or a related field
  • Excellent communication and teamwork skills

What We Offer:

  • Opportunity to work with a highly active phage-display group at the University of Nottingham
  • Collaboration with the Glycoweb team and international partners
  • Access to state-of-the-art facilities and equipment

How to Apply:

Applicants should submit their CV, cover letter, and academic transcripts to the University of Nottingham. The application deadline is [insert deadline].



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