Computational Biologist for Therapeutic Innovation

5 days ago


Oxford, Oxfordshire, United Kingdom Immunocore Full time
About the Company

Immunocore is a leading biotechnology company dedicated to developing innovative cancer therapies. Our mission is to harness the power of the immune system to treat cancer and other life-threatening diseases. With a strong focus on research and development, we aim to transform patients' lives through groundbreaking treatments.

The Principal Scientist In Silico Biologics Design will be part of our cutting-edge team, working closely with interdisciplinary teams across structural biology, next-generation sequencing (NGS), and bioinformatics and data science to integrate machine learning into TCR discovery and optimisation.

Key Responsibilities:

  • Develop and assess advanced machine learning models for novel antibody and TCR drug candidate optimisation.
  • Work with colleagues across Research to identify training data from the public domain and help shape the development of our in-house data sets to support the optimisation of ML algorithms.

Education & Qualifications:

  • PhD in Computational Biology, Computational Chemistry, Bioinformatics, or related discipline.

Payout: We estimate that this role offers a salary range of $140,000 - $200,000 per year.



  • Oxford, Oxfordshire, United Kingdom Northreach Full time

    Job Overview: We are seeking a highly skilled Computational Biologist to join our team. As a key member of our multidisciplinary scientific team, you will be responsible for conceptualising, designing, and implementing innovative data analysis strategies to advance our client's ERAP1 inhibitor-driven antigen discovery pipeline.Main Responsibilities-...


  • Oxford, Oxfordshire, United Kingdom Hlx Life Sciences Full time

    Hlx Life Sciences is seeking a highly experienced Senior Computational Biologist to join our team. As a Senior Computational Biologist, you will be responsible for developing models for computational protein engineering and collaborating with data scientists, bioinformaticians, protein engineers, and molecular biologists to create and continuously improve...


  • Oxford, Oxfordshire, United Kingdom Vertex Pharmaceuticals Full time

    Vertex PharmaceuticalsAt Vertex, we're committed to solving the toughest challenges in medicine. As a Senior Computational Biologist, you'll play a key role in driving our mission forward. This is an on-site or hybrid eligible position based out of our site in Oxford, UK, requiring at least 3 days/week onsite.We're seeking a highly skilled computational...

  • Research Biologist

    2 weeks ago


    Oxford, Oxfordshire, United Kingdom OBN Ltd Full time

    We are seeking a highly skilled Research Biologist to join our team at OMass Therapeutics in Oxford. As a Senior Scientist, you will play a key role in solving drug discovery challenges using your structural biology expertise and scientific curiosity.About the RoleThe successful candidate will work closely with our Protein Biochemistry & Structural Biology...


  • Oxford, Oxfordshire, United Kingdom Immunocore Full time

    Drive Innovation in Biologics Drug Discovery as a Data AnalystWe are seeking an experienced Data Analyst to join our Protein Engineering department at Immunocore. As a key member of our team, you will work closely with experimental biologists to design and automate the capture, organisation, and analysis of experimental data for biologics drug...


  • Oxford, Oxfordshire, United Kingdom Immunocore Full time

    Role and ResponsibilitiesAs a senior bioinformatician, you will work in interdisciplinary teams across protein engineering and bioinformatics to develop and integrate data science approaches into TCR and antibody discovery and optimisation. You will analyse, manage, and organise datasets generated across a protein engineering campaign, including...


  • Oxford, Oxfordshire, United Kingdom Immunocore Full time

    Job OverviewWe are seeking an experienced bioinformatician to work closely with Research and Bioinformatics/Data Science teams at Immunocore, a pioneering biotechnology company developing transformative medicines for oncology, infectious diseases, and autoimmune disease. The ideal candidate will be a driven, curious, and collaborative scientist passionate...


  • Oxford, Oxfordshire, United Kingdom Immunocore Full time

    About the Opportunity: As a Principal Research Scientist In Silico Biologics Design at Immunocore, you will have the opportunity to work at the forefront of computational therapeutics, driving innovation and excellence in the design of our T-cell receptor (TCR) drugs. With a strong focus on machine learning and in silico methodologies, you will be part of a...

  • Biologist Specialist

    3 weeks ago


    Oxford, Oxfordshire, United Kingdom Economicsnetwork Full time

    As a key member of the Economicsnetwork team, we are seeking a highly skilled Biologist Specialist to lead analysis of single-cell gene expression and open chromatin profiling data to investigate transcriptional regulation during Drosophila Melanogaster brain development.The successful candidate will work with experimental collaborators to answer questions...

  • Molecular Biologist

    2 weeks ago


    Oxford, Oxfordshire, United Kingdom Northreach Full time

    Cancer Immunotherapy Expert NeededWe are seeking a highly skilled Molecular Biologist to join our team, focused on developing novel cancer immunotherapies. As a key contributor, you will drive innovation and make a significant impact in the fight against cancer.About the PositionConduct experiments to generate and select yeast TCR display libraries,...


  • Oxford, Oxfordshire, United Kingdom University of Oxford Full time

    About the RoleWe are hiring a Data Science and Engineering Specialist to join our research group at the Department of Computer Science, University of Oxford. The successful candidate will have expertise in developing and deploying machine learning models and frameworks to analyze camera trap images of wild animals.The role involves collaborating with field...


  • Oxford, Oxfordshire, United Kingdom Northreach Full time

    Northreach is a leading recruitment agency in the Advanced Therapies sector.We strive to connect businesses with top talent and provide a personalized recruitment experience.About the CompanyOur client is a leader in antigen modulation through ERAP enzyme inhibition, a critical component of the antigen presentation pathway.The company is advancing a...


  • Oxford, Oxfordshire, United Kingdom Hlx Life Sciences Full time

    Senior BioinformaticianJob Overview:Hlx Life Sciences is seeking a senior bioinformatician to lead our protein design efforts. In this role, you will work on developing computational models for protein engineering and collaborating with a multidisciplinary team to design and optimize proteins for R&D projects.Key Responsibilities:Leading the development of...


  • Oxford, Oxfordshire, United Kingdom Hlx Life Sciences Full time

    **Job Title:** Senior BioinformaticianWe are seeking a highly skilled Senior Bioinformatician to join our team at Hlx Life Sciences.**About the Role:The successful candidate will collaborate with data scientists, bioinformaticians, protein engineers, and molecular biologists to develop models for computational protein engineering.The Senior Bioinformatician...


  • Oxford, Oxfordshire, United Kingdom Warman O'Brien Full time

    About UsWarman O'Brien is a pioneering genetic therapy platform company working towards advancing precision medicine and treating unmet neuromuscular diseases.We are looking for an experienced Senior Bioinformatics Scientist to join our team and contribute to our mission.Job Description:Design and implement bioinformatics workflows and tools for target and...


  • Oxford, Oxfordshire, United Kingdom University of Oxford Full time

    Computer Vision DeveloperWe are seeking a talented Computer Vision Developer to join our team at the University of Oxford. As part of the Morphocam project, you will be working on developing and releasing machine learning/AI tools to enable precise metrics measurements on camera trap images of wild animals.The successful post-holder will be responsible for...


  • Oxford, Oxfordshire, United Kingdom Cranleigh Scientific Ltd Full time

    Cranleigh Scientific Ltd is seeking a Senior Bioinformatician to implement computational tools for high-throughput biological data analysis. This role requires a strong understanding of large-scale omics data and computational biology techniques.Job DescriptionWork closely with the Cell Sciences Team to identify biological objectives and requirements.Develop...


  • Oxford, Oxfordshire, United Kingdom Theolytics Full time

    About UsTheolytics is a pioneering biotechnology company dedicated to transforming patients' lives through innovative oncolytic viral therapies. Our mission is to provide better outcomes for patients with limited treatment options, particularly those suffering from ovarian cancer, colorectal cancer, and hematological malignancies.Job DescriptionWe are...


  • Oxford, Oxfordshire, United Kingdom This is an IT support group Full time

    This role offers a unique opportunity to contribute to groundbreaking research in cardiovascular science at the Radcliffe Department of Medicine.As a Postdoctoral Research Associate, you will drive computational research to advance understanding of human heart disease, working closely with experts from diverse backgrounds.Key ResponsibilitiesLead...


  • Oxford, Oxfordshire, United Kingdom Warman O'Brien Full time

    We are looking for a Senior Bioinformatics Scientist to join our team at Warman O'Brien, an Oxford University spin-off early-stage genetic therapy platform company. As a member of our team, you will play a key role in advancing precision medicine by harnessing the power of protein isoforms.The successful candidate will have a PhD in Computational...