Lead Computational Chemist

7 days ago


Cambridge, Cambridgeshire, United Kingdom CK Group Full time

Job Summary

We are seeking an exceptional computational chemist and drug hunter to lead the Computational Chemistry team at CK Group. This is an exciting opportunity to leverage cutting-edge computational approaches in drug discovery projects and develop novel methodologies for wider utility.

About the Role

As Head of Computational Chemistry, you will manage a team of computational chemists supporting a diverse portfolio of internal and partnered projects. Your key responsibilities will include:

  • Ensuring scientific excellence of the computational chemistry team through effective line-management and mentoring, supporting delivery of key internal and partnered milestones.
  • Working with key stakeholders across other disciplines in CK Group to influence R&D strategy and define and execute high-quality computational strategies that enhance delivery of projects across the portfolio.
  • Driving continuous growth and development of cutting-edge SBDD & CADD methodologies.
  • Leading implementation of innovative computational solutions, including machine learning and AI approaches for in silico protein design.

Requirements

To be successful in this role, you will require:

  • Broad expertise in computational sciences with an emphasis on structure-based drug design (including GPCRs), ligand- and structure-based virtual screening, cheminformatics, and machine learning.
  • A track record of identifying, developing, and applying innovative solutions to scientific and technological problems faced in computational molecular design and in the wider drug discovery organisation.
  • Extensive knowledge of related disciplines (e.g. chemistry, biology, DMPK, safety) with demonstrable evidence of developing and implementing new scientific strategies in collaboration.
  • Proficiency in membrane protein structural modelling using the latest AI implementations.
  • Evidence of influencing project and organisational scientific strategy.

What We Offer

CK Group offers a competitive salary and benefits package to successful candidates.



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