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Lead Computational Chemist and Drug Hunter
2 months ago
Job Opportunity
We are seeking an exceptional computational chemist and drug hunter to lead our Computational Chemistry team at CK Group.
This is an exciting position, leveraging our expertise in computational approaches to lead drug discovery projects and develop novel methodologies for wider utility.
Our team is advancing an extensive pipeline of over 30 active programs from discovery through to late clinical stage, leveraging our unique and industry-leading GPCR-targeted structure-based drug discovery platform.
In this role, the successful candidate will:
- Ensure scientific excellence of the computational chemistry team through effective line-management and mentoring, supporting delivery of key internal and partnered milestones.
- Work with key stakeholders across other disciplines to influence R&D strategy and define and execute high-quality computational strategies that enhance delivery of projects across the portfolio.
- Drive continuous growth and development of cutting-edge SBDD & CADD methodologies.
- Lead implementation of innovative computational solutions, such as machine learning and AI approaches for in silico protein design.
- Support growth of our platform technology by implementing machine learning and AI approaches for in silico protein design.
Requirements:
As Head of Computational Chemistry, you will require:
- Evidence of broad expertise in computational sciences with an emphasis on structure-based drug design, including GPCRs, ligand- and structure-based virtual screening, cheminformatics, and machine learning.
- Track record of identifying, developing, and applying innovative solutions to scientific and technological problems faced in computational molecular design and in the wider drug discovery organization.
- Extensive knowledge of related disciplines, such as chemistry, biology, DMPK, safety, with demonstrable evidence of developing and implementing new scientific strategies in collaboration.
- Proficiency in membrane protein structural modelling using the latest AI implementations.
- Evidence of influencing project and organizational scientific strategy.
What We Offer:
A competitive salary and benefits package.
