Computational Chemist

23 hours ago


Cambridge, Cambridgeshire, United Kingdom SLS Services Limited Full time
Senior Computational Chemist

We are seeking a highly motivated and experienced Senior Computational Chemist to join our team at SLS Services Limited. As a key member of our drug discovery pipeline, you will be responsible for providing computational chemistry expertise to support the development of novel medicines for underserved diseases.

Key Responsibilities:

  • Conduct molecular dynamics simulations using OpenMM, AMBER, and GROMACS to inform drug discovery projects.
  • Develop and implement tools and workflows to extract, integrate, and analyse chemical, biophysical, and ADMET data.
  • Collaborate with cross-functional teams to support drug discovery projects and contribute to the development of computational chemistry technologies.
  • Train and support members of the discovery teams in the use of analysis and visualisation tools.

Qualifications:

  • Industry experience or postdoctoral experience in computational chemistry.
  • Practical knowledge of conducting and analysing molecular dynamics simulations.
  • Experience in QSAR virtual screening, amino acid and peptide modelling, and Free Energy Perturbation calculations.
  • Use of HPC and experience in writing analysis scripts and pipelines in Python.

Desirable Qualifications:

  • Knowledge of cheminformatics methods and databases.
  • Practical knowledge of quantum mechanical calculations.
  • Skills in machine learning, deep learning, statistical modelling, and advanced data analytics.


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