Lead Scientist in Quantitative Systems Pharmacology

3 weeks ago


Sheffield, Sheffield, United Kingdom Certara Full time
Overview

About Certara

Certara is an innovative organization that offers a vibrant and stimulating work environment. Our mission is to expedite the development of impactful therapies that benefit society and those in need. We highly value creativity and innovation, providing opportunities for ongoing training and professional growth. Our expertise encompasses the entire spectrum of drug development, from discovery through to post-marketing, collaborating with over 1,200 commercial entities, 250 academic institutions, and various regulatory bodies.

Certara enhances the drug development process through proprietary biosimulation software, advanced technology, and comprehensive services, transforming conventional approaches to drug discovery. Our clientele includes more than 2,000 biopharmaceutical firms, academic institutions, and regulatory agencies across 62 nations.

Responsibilities

The Quantitative Systems Pharmacology (QSP) division at Certara is a worldwide team dedicated to the effective application of QSP and mechanistic pharmacokinetic-pharmacodynamic (PKPD) modeling and simulation in the realm of drug discovery and development. We are at the forefront of pioneering QSP Consortia involving over 10 global pharmaceutical companies and are rapidly expanding our consultancy services. Our QSP scientists collaborate closely with other Certara professionals and clients to develop and utilize cutting-edge mechanistic models that facilitate informed decision-making in pharmaceutical research and development. These models are crafted in close partnership with clients and are designed to be user-friendly tools that guide drug development initiatives from initial discovery to regulatory submission. We possess a unique ability to seamlessly incorporate customized QSP models into the Simcyp physiologically based pharmacokinetic (PBPK) platform.

Qualifications

Requirements:

  • Postdoctoral experience in systems modeling for drug discovery and development teams.
  • PhD (or equivalent) in life sciences, engineering, computer science, mathematics, physics, or a related field.
  • Strong understanding of PKPD, pharmacology, and biology and their applications in drug discovery and development.
  • Extensive hands-on experience with Matlab, Neuron, or similar modeling software.
  • A robust publication record that reflects the level of experience.

Certara is committed to making all employment-related decisions based on merit, considering qualifications, skills, achievements, and performance. We ensure that all applicants and employees are treated fairly, without regard to personal characteristics such as race, color, ethnicity, religion, sex, sexual orientation, age, nationality, marital status, pregnancy, physical or mental condition, genetic information, military service, or any other characteristic protected by law.


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