Research Fellow

2 weeks ago

London, United Kingdom University College London Full time

**Ref Number**

B02-06591

**Professional Expertise**

Research and Research Support

**Department**

School of Life & Medical Sciences (B02)

**Location**

London

**Working Pattern**

Full time

**Salary**

£42,099-£50,585

**Contract Type**

Permanent

**Working Type**

On site (> 80% of working time)

**Available For Secondment**

No

**Closing Date**

18-Mar-2024

**About us**:
The Department of Neuromuscular Diseases is a hub for clinical and research excellence across the spectrum of spinal cord and neuromuscular diseases. Our group of world-leading clinical, genetic, and basic science researchers focus their work on understanding the causes and biological mechanisms leading to neuromuscular diseases and translating this knowledge into developing novel therapeutic solutions that is of direct benefit to neurological disorders such as motor neurone disease, Alzheimer’s disease, and neuromuscular disease.

The Fratta Laboratory, based in the department focuses on understanding and developing therapeutic approaches for motor neuron diseases. The laboratory uses a combination of iPSC neurons, postmortem patient brain and mouse models to identify early splicing changes that are relevant to the disease and investigate novel approaches to correct them.

**About the role**:
We have two exciting opportunities for a Research Fellow with expertise in RNA Biology. You will investigate Molecular Dysfunction and Novel Gene Therapy Approaches for Amyotrophic lateral sclerosis (ALS). This research will be conducted in a laboratory that combines cellular biology, molecular biology, and bioinformatics to address fundamental questions with translational relevance. The project will involve the use of cell lines, iPSC-derived neurons, and mice, to test cutting-edge approaches.

The posts are available from April 2024 and are funded by awards from LifeArc and Crick for two years in the first instance.

A full job description and person specification for this role can be accessed below.

**About you**:
You will hold a PhD degree in Molecular Biology, Neuroscience, or a related field, along with experience in library preparation for RNA-sequencing and other HT transcriptomic approaches. Additionally, experience in gene therapy, molecular cloning, and coding will be essential.

You will need to have strong written and verbal communication skills, excellent problem-solving abilities, good interpersonal skills, and be able to act on your initiative while being committed to supporting high-quality research.

**What we offer**:
Appointment as Research Fellow is dependent upon having been awarded a PhD; if this is not the case, initial appointment will be as Research Assistant (salary £37,332 - £39,980 per annum) with appointment as Research Fellow being backdated to the date of final submission of the PhD thesis.

As well as the exciting opportunities this role presents, we also offer great benefits, some of which are below:

- 41 Days holiday (27 days annual leave 8 bank holiday and 6 closure days)
- Additional 5 days’ annual leave purchase scheme
- Defined benefit career average revalued earnings pension scheme (CARE)
- Cycle to work scheme and season ticket loan
- Immigration loan
- Relocation scheme for certain posts
- On-site nursery
- On-site gym
- Enhanced maternity, paternity and adoption pay
- Employee assistance programme: Staff Support Service
- Discounted medical insurance

**Our commitment to Equality, Diversity and Inclusion**:
The Institute prides itself on operating in an all-inclusive environment irrespective of personal, physical, or social characteristics. Teamwork is highly valued, individual strengths are recognised and celebrated, and we are committed to advancing the careers of everyone. 12% of Institute staff are actively working on Equality, Diversity and Inclusion (EDI) initiatives; visit our EDI website for more information about our initiatives and priorities. The Institute also holds an Athena SWAN Silver award, in recognition of our commitment and demonstrable impact in advancing gender equality.

As London’s Global University, we know diversity fosters creativity and innovation, and we want our community to represent the diversity of the world’s talent. We are committed to equality of opportunity, to being fair and inclusive, and to being a place where we all belong.

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