Research Fellow

4 weeks ago

London, United Kingdom University College London Full time

**Ref Number**

B02-06151

**Professional Expertise**

Research and Research Support

**Department**

School of Life & Medical Sciences (B02)

**Location**

London

**Working Pattern**

Full time

**Salary**

See advert text

**Contract Type**

Permanent

**Working Type**

Hybrid (20% - 80% on site)

**Available For Secondment**

No

**Closing Date**

10-Dec-2023

**About us**:
The Wiseman lab aims to understand the development of Alzheimer’s disease in individuals who have Down syndrome (DS-AD) to inform the development and selection of therapies for this important group of individuals who are at greatly increased risk of disease. Specifically, the lab is interested in understanding how the additional copy of genes on chromosome 21, other than APP, modulate disease development. The broad focus of the lab is to understand the modulation of APP/amyloid-β generation and response and how this contributes to synapse loss and disease-relevant cognitive functions like memory, compulsive behaviour and anxiety and apathy.

**About the role**:
We are looking for a highly motivated Research Fellow to undertake a proteomic-neuropathology project as part of an international collaborative project (Wiseman Lab, UCL, Ryan, Fox and Lashley, UCL, UK DRI Biomarkers Factory, Strydom Lab, KCL, and Poiter Lab, ICM, Paris).

You will analyse amyloid-β proteomic data from cases of AD-AD and determine the relationship between a novel amyloid-β species and cerebral amyloid angiopathy (CAA) load, as well as test a newly developed anti-amyloid-β antibody for its specificity for cerebral amyloid angiopathy (CAA), in cases of DS-AD, FAD and sporadic EOAD.

Also, you will coordinate this work with related work being undertaken in the group of Marie-Claude Potier (ICM, Paris), Andre Strydom (KCL) and the UK DRI Biomarkers Factory, in addition to communicating research findings to collaborative partners and study participants.

The post is available from 01 March 2024 and funded by the UK DRI for one year in the first instance.

This role is eligible for hybrid working with a minimum of 80% on site.

A full job description and person specification for this role can be accessed below.

**About you**:
**What we offer**:
Starting salary offered at £42,099 per annum.

Appointment as Research Fellow is dependent upon having been awarded a PhD; if this is not the case, initial appointment will be as Research Assistant (salary £37,332 - £39,980 per annum) with appointment as Research Fellow being backdated to the date of final submission of the PhD thesis.

As well as the exciting opportunities this role presents, we also offer great benefits, some of which are below:

- 41 Days holiday (27 days annual leave 8 bank holiday and 6 closure days)
- Additional 5 days’ annual leave purchase scheme
- Defined benefit career average revalued earnings pension scheme (CARE)
- Cycle to work scheme and season ticket loan
- Immigration loan
- Relocation scheme for certain posts
- On-site nursery
- On-site gym
- Enhanced maternity, paternity and adoption pay
- Employee assistance programme: Staff Support Service
- Discounted medical insurance

**Our commitment to Equality, Diversity and Inclusion**:
The Institute prides itself on operating in an all-inclusive environment irrespective of personal, physical, or social characteristics. Teamwork is highly valued, individual strengths are recognised and celebrated, and we are committed to advancing the careers of everyone. 12% of Institute staff are actively working on Equality, Diversity and Inclusion (EDI) initiatives; visit our EDI website for more information about our initiatives and priorities. The Institute also holds an Athena SWAN Silver award, in recognition of our commitment and demonstrable impact in advancing gender equality.

As London’s Global University, we know diversity fosters creativity and innovation, and we want our community to represent the diversity of the world’s talent. We are committed to equality of opportunity, to being fair and inclusive, and to being a place where we all belong.

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