Immunopeptidomics Lc-ms Specialist

6 months ago


Oxford, United Kingdom Infinitopes Full time

The problem:
In the time it takes you to read this, 100 people around the world will have died from cancer. 20 cancer deaths every minute. 10 million people every year. With your help, we’re going to reduce that. Significantly.

**Us**:Oxford’s pioneering cancer biotech.

Infinitopes is a pioneer in precision immunomics medicine, leading advanced strategies to combat cancer. As a distinguished biotech spinout from Oxford University, in partnership with Cancer Research UK (CRUK), we're dedicated to leveraging the immune system's potential to target cancer metastases effectively. Through innovative antigen discovery technologies, alongside sophisticated high-efficiency delivery systems and thoughtfully crafted clinical trial designs, we're reshaping the landscape of cancer treatment. Our mission is to significantly enhance patient survival.

**You**:We are seeking an experienced Immunopeptidomics scientist to join our innovative discovery team, working in a state-of-the-art mass spectrometry laboratory.

Role Requirements:

- PhD or equivalent in quantitative biology, biochemistry, or related fields.
- Minimum 5 years of documented experience in modern mass spectrometry instrumentation.
- Strong background in mass spectrometry and quantitative proteomics, with expertise in immunopeptidomic research and target validation MS methods.
- Proficiency in DDA, DIA, PRM, and downstream analysis using tools. e.g. Peaks, MaxQuant, and Skyline.
- Solid understanding of basic biochemistry and molecular biology relevant to proteomics and immunopeptidomics.
- Excellent organisational and interpersonal skills, with a proven ability to collaborate effectively in team environments.

Core Responsibilities:

- Support the seamless data acquisition processes in our LC-MS laboratory.
- Optimise ultra-low input methods for DDA, DIA and PRM, collaborating with leading instrument technology manufacturers.
- Support sample preparation of large cohorts for LC-MS analysis.
- Maintain equipment and liaise with service and engineering teams.
- Manage budgeting and ordering of consumables for the LC-MS.
- Engage in outward-facing activities, including presentations and conference attendance.
- Contribute to training activities, providing technical guidance to less experienced staff.
- Drive technological developments in immunopeptidomics, with opportunities to access grant funding.

Management / leadership experience:

- Previous experience working in mass spectrometry facilities/labs or services in industry and academia.
- Previous experience working in teams and providing training and support for junior or less experienced staff.

Location / office requirements:

- The majority of the work will require travel to the Infinitopes HQ and roles will be split between the lab and office based
- Working from home is permitted.

How we value you and your growth:

- Leaving your mark on the next generation of life-changing precision medicines
- Empowering you to lead and unlock the potential of our team of rising stars
- Offering you a unique start-up career, tailored to your growth trajectory and personal interests with extensive internal & external training opportunity - we want to grow you into the next new leader, innovator, visionary or more
- Attractive salary, plus potentially life-changing share options

Next step:
Pay: £55,000.00-£60,000.00 per year

**Benefits**:

- Company pension
- Cycle to work scheme
- Employee stock ownership plan
- Health & wellbeing programme
- On-site parking
- Sick pay
- UK visa sponsorship

Schedule:

- Monday to Friday

**Education**:

- PhD (preferred)

Work Location: In person


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