Senior Bioinformatics Specialist
3 weeks ago
Job Summary
The Senior Bioinformatician will play a pivotal role in the conceptualization, design, and implementation of innovative data analysis strategies to advance the Company's ERAP1 inhibitor-driven antigen discovery pipeline.
Key Responsibilities
- Contribute to developing and maintaining high-quality nextflow pipelines for processing large-scale mass spectrometry data.
- Define objectives and perform statistical analysis of data-dependent (DDA) and data-independent (DIA) immunopeptidomics assays.
- Conduct analysis of parallel reaction monitoring (PRM) peptide assays.
- Integrate antigen discovery workflows with transcriptomic and genomic data.
- Leverage external resources and databases to enhance internal workflows and improve target prioritization.
- Stay at the forefront of scientific advances in mass spectrometry-based immunopeptidomics and antigen presentation, including software and new methodologies.
- Lead and manage analytical aspects of projects, including data preparation, analysis, and visualization.
- Provide data-driven insights to inform experimental design.
- Communicate research findings to both technical and non-technical audiences, internally and externally.
Requirements
- PhD (or equivalent experience) in bioinformatics, immunology, computational biology, or a related field.
- In-depth knowledge of mass spectrometry-based proteomics data acquisition and processing, with familiarity in data-dependent and data-independent methods preferred.
- Strong knowledge of machine learning and/or multivariate statistical modeling.
- Proficiency in statistical programming and building statistical models.
- Expertise in R or Python programming.
- Extensive experience in large-scale bioinformatics analysis of omics data.
- Proficient in Linux OS and shell scripting.
- Experience with building and running analytical pipelines using NextFlow and Docker.
- Ability to analyze, interpret, and record findings efficiently and in compliance with standards.
- Strong communication skills, capable of conveying complex topics to diverse audiences.
- Proven success working in multidisciplinary scientific teams (desirable).
- Familiarity with cloud infrastructure (e.g., AWS) is a plus.
- Deep understanding of antigen processing (desirable).
- Prior research experience in an industrial setting (desirable).
- Knowledge of molecular biology, cell biology, or immunology (desirable).
Northreach is an equal opportunity employer and we do not discriminate against any employee or applicant for employment based on race, colour, religion, sex, national origin, disability, or age. We are committed to promoting diversity, equity, and inclusion in the workplace and hiring practices, therefore only partner with business that promote DEI. We strive to create a welcoming and inclusive environment for all employees.
-
Senior Bioinformatics Specialist
4 weeks ago
Oxford, Oxfordshire, United Kingdom Warman O'Brien Full timeSenior Bioinformatics SpecialistWe are seeking a highly skilled Senior Bioinformatics Specialist to join our team at Warman O'Brien. The successful candidate will be responsible for designing, implementing, and improving our bioinformatics capabilities, including new workflows and tools required for target and drug discovery.Key Responsibilities:Collaborate...
-
Senior Bioinformatics Specialist
4 weeks ago
Oxford, Oxfordshire, United Kingdom Warman O'Brien Full timeSenior Bioinformatics SpecialistWe are working with an exciting startup that is looking for an experienced Bioinformatics Specialist to lead a project.The ideal candidate will have experience analyzing long read RNA sequencing datasets and working on Isoform Discovery / Gene Annotations projects.Key Responsibilities:Lead the project and ensure timely...
-
Senior Bioinformatics Specialist
4 weeks ago
Oxford, Oxfordshire, United Kingdom Oxford Nanopore Technologies Full timeRole OverviewWe are seeking a highly skilled Senior Bioinformatics Specialist to join our team at Oxford Nanopore Technologies. The successful candidate will have extensive experience in the analysis of second and third generation sequencing data in the context of human disease.The role will sit at a pivotal junction of R&D, Applications, technical support,...
-
Senior Bioinformatics Specialist
3 weeks ago
Oxford, Oxfordshire, United Kingdom Oxford Nanopore Technologies Full timeKey ResponsibilitiesWe are seeking a highly skilled Senior Bioinformatics Specialist to join our team at Oxford Nanopore Technologies. The successful candidate will have extensive experience in the analysis of second and third generation sequencing data in the context of human disease.The role will sit at a pivotal junction of R&D, Applications, technical...
-
Senior Bioinformatics Specialist
4 weeks ago
Oxford, Oxfordshire, United Kingdom Oxford Nanopore Technologies Full timeJob SummaryWe are seeking a highly skilled Senior Bioinformatics Specialist to join our team at Oxford Nanopore Technologies. The successful candidate will have extensive experience in analyzing second and third generation sequencing data in the context of human disease.The role will involve evaluating the performance of internal and community analysis tools...
-
Senior Bioinformatics Specialist
4 weeks ago
Oxford, Oxfordshire, United Kingdom Warman O'Brien Full timeJob DescriptionSenior Bioinformatics SpecialistWe are working with an exciting startup that is looking for an experienced Bioinformatician to lead a project.The ideal candidate will have experience analysing long read RNA sequencing datasets and working on Isoform Discovery / Gene Annotations projects.Key responsibilities include:Leading the project and...
-
Bioinformatics Specialist
4 weeks ago
Oxford, Oxfordshire, United Kingdom Oxford Nanopore Technologies Full timeOxford Nanopore Technologies is a leading innovator in the field of nanopore sequencing, with a mission to enable the analysis of any living thing, by anyone, anywhere.The company is seeking a highly skilled Bioinformatics Specialist to join its Sample Technology team, within the R&D department. The successful candidate will be responsible for developing and...
-
Senior Bioinformatics Researcher
3 weeks ago
Oxford, Oxfordshire, United Kingdom EIT Pathogena Full timeAbout EIT PathogenaWe are a cutting-edge research and development facility that bridges the gap between technology and humanity's most pressing challenges.Our mission is to develop and deploy advanced bioinformatics solutions to revolutionize the diagnosis and treatment of infectious diseases.We are seeking a talented Senior Bioinformatics Researcher to join...
-
Bioinformatics Specialist
4 weeks ago
Oxford, Oxfordshire, United Kingdom Oxford Nanopore Technologies Full timeOxford Nanopore Technologies is a leading developer of innovative sequencing technologies. We are seeking a highly skilled Bioinformatician to join our Sample Technology team, which drives revenue growth through the research and development of tools, techniques, and workflows for our disruptive sequencing devices.The ideal candidate will have practical...
-
Senior Bioinformatics Specialist
1 week ago
Oxford, Oxfordshire, United Kingdom Immunocore Full timeKey ResponsibilitiesWe are seeking a highly skilled Bioinformatics Analyst to join our team of experts in cancer research. The successful candidate will be responsible for providing focused bioinformatics support to our research teams, including conducting bioinformatics analysis to draw insights from publicly available and experimental data.Key...
-
Bioinformatics Quality Assurance Specialist
4 weeks ago
Oxford, Oxfordshire, United Kingdom Oxford Nanopore Technologies Full timeAbout the RoleOxford Nanopore Technologies is a leading innovator in the field of nanopore sequencing, with a strong presence in the UK and globally. Our team is comprised of experts from various disciplines, including nanopore science, molecular biology, informatics, engineering, and commercialization.We are seeking a highly skilled Bioinformatics Quality...
-
Bioinformatics Quality Assurance Specialist
4 weeks ago
Oxford, Oxfordshire, United Kingdom Oxford Nanopore Technologies Full timeOxford Nanopore Technologies is a leading developer of innovative sequencing technologies. We are seeking a highly skilled Bioinformatics Quality Assurance Specialist to join our Customer Workflows Group.The ideal candidate will have a strong background in bioinformatics and quality assurance practices, ensuring the accuracy, reliability, and compliance of...
-
Bioinformatics Quality Assurance Specialist
3 weeks ago
Oxford, Oxfordshire, United Kingdom Oxford Nanopore Technologies Full timeOxford Nanopore Technologies is a leading company in the field of nanopore sequencing technologies, with a strong presence in the UK and global locations across the US, APAC, and Europe. The company employs experts from various fields, including nanopore science, molecular biology, informatics, engineering, electronics, manufacturing, and...
-
Senior Bioinformatics Specialist
4 weeks ago
Oxford, Oxfordshire, United Kingdom EIT Pathogena Full timeAbout EIT PathogenaEIT Pathogena is a pioneering research and development facility that leverages advanced technology to tackle humanity's most pressing challenges. Guided by world-leading scientists and entrepreneurs, we drive innovation by pushing the boundaries of scientific and technological advancements in four key areas: health and medical science,...
-
Bioinformatics Specialist
4 weeks ago
Oxford, Oxfordshire, United Kingdom Oxford Nanopore Technologies Full timeOxford Nanopore Technologies is a leading innovator in the field of nanopore sequencing technologies. We are seeking a highly skilled Bioinformatician to join our Sample Technology team within the R&D department.The successful candidate will have a strong background in bioinformatics and experience in handling and analysing large next-generation sequencing...
-
Senior Bioinformatics Specialist
3 weeks ago
Oxford, Oxfordshire, United Kingdom Northreach Full timeAbout the RoleWe are seeking a highly skilled Senior Bioinformatician to join our multidisciplinary scientific team at Northreach. As a key member of the core team, you will play a pivotal role in advancing our ERAP1 inhibitor-driven antigen discovery pipeline.Key ResponsibilitiesDesign and implement innovative data analysis strategies to drive our research...
-
Bioinformatics Specialist
3 weeks ago
Oxford, Oxfordshire, United Kingdom Oxford Nanopore Technologies Full timeOxford Nanopore Technologies is a leading innovator in the field of nanopore sequencing technologies. We are seeking a highly skilled Bioinformatician to join our Sample Technology team, within the R&D department.The successful candidate will have a strong background in bioinformatics and experience in handling and analysing large next-generation sequencing...
-
Senior Bioinformatics Specialist
3 weeks ago
Oxford, Oxfordshire, United Kingdom Northreach Full timeCompany OverviewNorthreach is a dynamic recruitment agency that connects businesses with top talent in the Advanced Therapies sector. Our mission is to provide a seamless and personalized recruitment experience for clients and candidates, and to create a positive work environment that encourages equality, innovation, and professional growth.Job SummaryThe...
-
Clinical Bioinformatics Specialist
3 weeks ago
Oxford, Oxfordshire, United Kingdom University of Oxford Full timeClinical Bioinformatics Role OverviewThe University of Oxford seeks a highly skilled bioinformatician to join our team in the development and implementation of clinical bioinformatics solutions. This exciting opportunity is part of the Oxford Molecular Diagnostics Centre, which focuses on developing and providing novel genomics technologies for clinical...
-
Senior Bioinformatics Scientist
2 weeks ago
Oxford, UK, Oxfordshire, United Kingdom Cranleigh STEM, Sustainability & SHEQ Recruitment Full timeOur startup client is seeking a Senior Bioinformatician to join their team. Their aim is to revolutionize omics-based screening strategies for discovering novel biological targets.As a bioinformatics specialist, you’ll bring extensive knowledge of large-scale omics data, playing a central role in implementing computational tools to analyze high-throughput...