Senior Bioinformatics Specialist

2 weeks ago


Oxford, Oxfordshire, United Kingdom Northreach Full time
Opportunity in Antigen Discovery

Northreach is a dynamic recruitment agency that connects businesses with top talent in the Advanced Therapies sector. Our mission is to provide a seamless and personalized recruitment experience for clients and candidates, and to create a positive work environment that encourages equality, innovation, and professional growth.

Our client is a leader in antigen modulation through ERAP enzyme inhibition, with an ERAP1 inhibitor in Phase I/II clinical trials and another expected to enter Phase I for autoimmune indications in 2025. They are advancing a hit-to-lead program targeting ERAP2 and exploring the translational potential of ERAP enzyme inhibition.

Job Responsibilities
  • Design and implement innovative data analysis strategies to advance the antigen discovery pipeline.
  • Analyze large-scale datasets, including immunopeptidomic, transcriptomic, and genomic data, to identify ERAP1 inhibitor-dependent targets.
  • Collaborate with a multidisciplinary scientific team to oversee all aspects from in-silico antigen discovery to experimental validation.
Requirements
  • PhD in bioinformatics, immunology, computational biology, or a related field.
  • Expertise in mass spectrometry-based proteomics data acquisition and processing, with familiarity in data-dependent and data-independent methods.
  • Strong knowledge of machine learning and/or multivariate statistical modeling.
  • Proficiency in R or Python programming.
  • Experience in large-scale bioinformatics analysis of omics data.
  • Ability to analyze, interpret, and record findings efficiently and in compliance with standards.
  • Strong communication skills, capable of conveying complex topics to diverse audiences.
Additional Information

The successful candidate will have a deep understanding of antigen processing and be able to contribute to the company's overarching goals. The salary for this position is estimated at $120,000 per annum, depending on location and experience.



  • Oxford, Oxfordshire, United Kingdom Oxford Nanopore Technologies Full time

    Key ResponsibilitiesWe are seeking a highly skilled Senior Bioinformatics Specialist to join our team at Oxford Nanopore Technologies. The successful candidate will have extensive experience in the analysis of second and third generation sequencing data in the context of human disease.The role will sit at a pivotal junction of R&D, Applications, technical...


  • Oxford, Oxfordshire, United Kingdom Oxford Nanopore Technologies Full time

    Job DescriptionOxford Nanopore Technologies, a global leader in DNA sequencing technology, seeks a highly skilled Bioinformatics Quality Assurance Specialist to join its Customer Workflows Group. Located at the Oxford Science Park, this role offers an attractive bonus, generous pension contributions, private healthcare, and an excellent starting salary of...


  • Oxford, Oxfordshire, United Kingdom EIT Pathogena Full time

    About EIT PathogenaWe are a cutting-edge research and development facility that bridges the gap between technology and humanity's most pressing challenges.Our mission is to develop and deploy advanced bioinformatics solutions to revolutionize the diagnosis and treatment of infectious diseases.We are seeking a talented Senior Bioinformatics Researcher to join...


  • Oxford, Oxfordshire, United Kingdom EIT Pathogena Full time

    About EIT PathogenaEIT Pathogena is a pioneering research facility that seeks to revolutionize the diagnosis and treatment of infectious diseases through cutting-edge bioinformatics solutions.We are a multidisciplinary team of experts working closely with the University of Oxford to develop Whole Genome Sequencing-based metagenomic and individual pathogen...


  • Oxford, Oxfordshire, United Kingdom Immunocore Full time

    Key ResponsibilitiesWe are seeking a highly skilled Bioinformatics Analyst to join our team of experts in cancer research. The successful candidate will be responsible for providing focused bioinformatics support to our research teams, including conducting bioinformatics analysis to draw insights from publicly available and experimental data.Key...


  • Oxford, Oxfordshire, United Kingdom Oxford Nanopore Technologies Full time

    Oxford Nanopore Technologies is a leading company in the field of nanopore sequencing technologies, with a strong presence in the UK and global locations across the US, APAC, and Europe. The company employs experts from various fields, including nanopore science, molecular biology, informatics, engineering, electronics, manufacturing, and...


  • Oxford, Oxfordshire, United Kingdom Oxford Nanopore Technologies Full time

    Oxford Nanopore Technologies is a leading provider of innovative sequencing technologies. We are seeking a highly skilled Bioinformatics Quality Assurance Specialist to join our team in the Customer Workflows Group.Key ResponsibilitiesImplement and maintain quality assurance protocols and procedures for bioinformatics software, data analysis pipelines, and...


  • Oxford, Oxfordshire, United Kingdom Northreach Full time

    About the RoleWe are seeking a highly skilled Senior Bioinformatician to join our multidisciplinary scientific team at Northreach. As a key member of the core team, you will play a pivotal role in advancing our ERAP1 inhibitor-driven antigen discovery pipeline.Key ResponsibilitiesDesign and implement innovative data analysis strategies to drive our research...


  • Oxford, Oxfordshire, United Kingdom Oxford Nanopore Technologies Full time

    Oxford Nanopore Technologies is a leading innovator in the field of nanopore sequencing technologies. We are seeking a highly skilled Bioinformatician to join our Sample Technology team, within the R&D department.The successful candidate will have a strong background in bioinformatics and experience in handling and analysing large next-generation sequencing...


  • Oxford, Oxfordshire, United Kingdom University of Oxford Full time

    Clinical Bioinformatics Role OverviewThe University of Oxford seeks a highly skilled bioinformatician to join our team in the development and implementation of clinical bioinformatics solutions. This exciting opportunity is part of the Oxford Molecular Diagnostics Centre, which focuses on developing and providing novel genomics technologies for clinical...


  • Oxford, Oxfordshire, United Kingdom Northreach Full time

    Company OverviewNorthreach is a dynamic recruitment agency that connects businesses with top talent in the Advanced Therapies sector. Our mission is to provide a seamless and personalized recruitment experience for clients and candidates, and to create a positive work environment that encourages equality, innovation, and professional growth.Job SummaryThe...


  • Oxford, UK, Oxfordshire, United Kingdom Cranleigh STEM, Sustainability & SHEQ Recruitment Full time

    Our startup client is seeking a Senior Bioinformatician to join their team. Their aim is to revolutionize omics-based screening strategies for discovering novel biological targets.As a bioinformatics specialist, you’ll bring extensive knowledge of large-scale omics data, playing a central role in implementing computational tools to analyze high-throughput...


  • Oxford, Oxfordshire, United Kingdom Oxford Nanopore Technologies Full time

    About the RoleWe are seeking a highly motivated and experienced Human Genetics Bioinformatics Specialist to join our team at Oxford Nanopore Technologies. As a key member of our Applications group, you will play a pivotal role in evaluating the performance of our internal and community analysis tools on Nanopore data, working closely with internal and...


  • Oxford, Oxfordshire, United Kingdom Oxford Nanopore Technologies Full time

    About the RoleWe are seeking a dedicated and detail-oriented Bioinformatics Quality Assurance Specialist to join our team at Oxford Nanopore Technologies. This is an exciting opportunity to work on cutting-edge bioinformatics software and to contribute to the development of high-quality products.In this role, you will be responsible for implementing QA...


  • Oxford, Oxfordshire, United Kingdom Oxford Nanopore Technologies Full time

    At Oxford Nanopore Technologies, we are seeking a talented Bioinformatician to join our Sample Technology team within the R&D department.The successful candidate will have a strong background in bioinformatics, with practical experience in handling and analysing large next-generation sequencing data sets.They will have a history of involvement in the...


  • Oxford, Oxfordshire, United Kingdom Oxford Nanopore Technologies Full time

    The Customer Analysis Workflows group at Oxford Nanopore Technologies is responsible for developing and maintaining new bioinformatic analyses to be coupled with particular experiment scenarios, targeting particular scientific and clinical questions. Key responsibilities include taking ownership of newly identified workflows and collaborating with the team...


  • Oxford, Oxfordshire, United Kingdom Oxford Nanopore Technologies Full time

    About the RoleWe are seeking an experienced Human Genetics Bioinformatics Solutions Specialist to join our team at Oxford Nanopore Technologies. As a key member of our R&D, Applications, and Commercial teams, you will be responsible for evaluating the performance of internal and community analysis tools on Nanopore Data.Responsibilities• Evaluate, plan,...


  • Oxford, Oxfordshire, United Kingdom Oxford Nanopore Technologies Full time

    Oxford Nanopore Technologies is a global leader in real-time nanopore-based DNA/RNA sequencing technology. Our goal is to enable the analysis of any living thing, by anyone, anywhere.The Customer Analysis Workflows group at Oxford Nanopore Technologies' is responsible for communicating bioinformatic analyses to end users through various media. We are seeking...


  • Oxford, Oxfordshire, United Kingdom Oxford Nanopore Technologies Full time

    Key ResponsibilitiesWe are seeking an experienced Human Genetics Bioinformatics Applications Specialist to join our team at Oxford Nanopore Technologies. The successful candidate will have a strong background in human genetics bioinformatics and experience in developing analysis tools and/or pipelines for long read sequencing data. Key responsibilities...


  • Oxford, Oxfordshire, United Kingdom Oxford Nanopore Technologies Full time

    Job OverviewOxford Nanopore Technologies is a pioneering company in the field of nanopore sequencing, with headquarters at the Oxford Science Park and satellite offices globally.Key Responsibilities:Develop and maintain bioinformatic analyses to support scientific research and customer applications.Collaborate with cross-functional teams to identify analysis...