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Research Assistant in Stem Cells
3 months ago
Role overview
- We seek a motivated Research Assistant with experience in mammalian cell culture to support and advance the human developmental and stem cell biology research programme within the Rugg-Gunn team at the Babraham Institute.
The research project is aimed at optimising and validating methods to genetically engineer human pluripotent stem cell lines, with the overall goal of providing an efficient process to tag genes of interest with protein epitope and degradation sequences.
Genetically-engineered cell lines are important reagents that allow target protein function to be investigated using rapid and inducible degradation systems, in addition to enabling protein interaction and occupancy studies by using epitope tags.
This project will build on our existing experience of creating targeted knock-out and knock-in human pluripotent stem cell lines and will compare and optimise different gene editing and protein degradation methods.
The resultant modified cell lines will be used to generate stem cell-based embryo models called 'blastoids' and 'gastruloids', which mimic features of early embryo development.
The job holder will also work with team members to produce bioengineered scaffolds that can support the- _in vitro_ development of embryo models and of early-stage human embryos that have been generously donated to our research programme. The successful completion of this work will make important collaborative contributions to many of the group's research projects and will further our understanding of human developmental epigenetics.-
This is a fixed term, full-time appointment with funding for this post expected to be available for a period of up to three years.The Institute has joined the Technician Commitment initiative, which is a commitment to support the recognition, visibility, sustainability and career development of our research support community, including Research Assistants.
For more information on the work of the group, please visit here.-
th
June 2023.
NO AGENCIES PLEASE
- The Babraham Institute holds a silver Athena SWAN award and is committed to promoting and developing a culture of excellence, diversity and mutual respect that supports the Institute's ambitions and attracts highly motivated and talented people. _
- The Babraham Institute abides by the principles of the government's Disability Confident Scheme and has a positive approach to employing disabled people._
Department
Epigenetics
Contract type
Fixed Term Contract
Hours
37
Salary
Starting salary is £29,822 per annum to £32,240 per annum (depending on experience)
