Senior Scientific Officer

1 month ago


Glasgow, United Kingdom CRUK Scotland Institute Full time

About us

The CRUK Scotland Institute is a cancer research institute, situated in Glasgow with approximately 250 researchers split across 30 research groups consisting of PIs, postdoctoral scientists, PhD students and scientific officers. It is one of Europe's leading cancer research centres, supporting cutting-edge work into the molecular mechanisms of cancer development. As well as core support from Cancer Research UK, the Institute also receives an additional third of its total income from external grants and industry collaborations. It has an excellent reputation for fundamental cancer research, including world-class metabolism studies and renowned in vivo modelling of tumour growth and metastasis. Its research ethos is about excellence, honesty, openness, accountability and integrity.

Position outline

We currently have an exciting opportunity with a vacancy for a Senior Scientific Officer in our Transgenic Technologies team. The primary role of this position will be to support state-of the-art creation of genetically engineered in vivo cancer models designed for discovery research.

You will be expected to work as part of a collaborative team, conducting procedures required for the generation and maintenance of new transgenic cancer models. New cancer models will be created using a combination of CRISPR genome editing and gene targeting in embryonic stem (ES) cells. This will require the successful applicant to contribute to carrying out a variety of pre-implantation embryo manipulation techniques including microinjection, cryopreservation and in vitro fertilisation (IVF). This role may also involve culture of ES cells, DNA cloning, PCR genotyping, colony management and the importation of cryopreserved materials for rederivation.

You should be able to work both independently and in close collaboration with the research scientists and scientific officers involved with the transgenic projects. You should be highly motivated and have good communication and organisational skills. A flexible approach to your working pattern is necessary as there may be some weekend work required as part of this role.

You will possess a bachelor’s or master’s degree in molecular genetics or similar and have a good understanding of the molecular genetic techniques underlying gene targeting and CRISPR genome editing. Previous experience of pre-implantation embryo handling and microinjection would be a significant advantage, however, we can provide the necessary training for candidates who can demonstrate some lab experience, great attention to detail and the capability to perform intricate procedures. You should also possess excellent troubleshooting, planning/organisational capability and have a relevant scientific background. For informal enquiries or to discuss further, please email Dr Douglas Strathdee: d.strathdee@CRUKScotlandInstitute.ac.uk

Employee Benefits

  • Competitive salary
  • 40.5 days annual leave including bank holidays (pro-rata)
  • Defined Contribution pension scheme
  • Life Insurance scheme
  • Employee Assistance Programme
  • Season ticket loan
  • Additional maternity pay at 6 month’s full pay (subject to service)
  • Shared parental leave
  • Cycle to work scheme that could save you 26-40% on a bike and accessories.
  • Access to Employee benefit schemes with discounts on supermarkets, cinema, travel and much more.
  • On-site secure parking 

All applications must be made via our website by clicking on the 'Apply' button above.

Closing Date for Applications: 08/09/2024

£28,344 to £45,357 depending on qualification and experience



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