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Advanced Cell Therapies Manager
2 months ago
Job summary
NHSBT is developing a range of novel cell and gene therapies through clinical trials in collaboration with commercial and academic partners. This role offers the ideal candidate a great opportunity to use their extensive knowledge and experience to oversee the manufacture and delivery of these new therapies across several sites for the benefit of patients.
This new national post reflects the increasing activity of NHSBT in developing and delivering new cell therapies such as CAR-T cells under MHRA MIA(IMP) license in partnership with a range of sponsors and customers.Reporting to the Assistant Director for Cellular and Molecular Therapies (CMT), the post holder will work closely with senior Heads of Manufacturing units, quality assurance colleagues and others to ensure products are developed and delivered to meet financial, contractual, and regulatory requirements. The development of novel cell and gene therapies is an exciting and expanding area of medicine and this position offers the opportunity to deliver these therapies through clinical trial directly within the NHS.
This will be a Hybrid working role based at one of the NHSBT centres such as Birmingham, Bristol, Barnsley, Liverpool, or Oxford. However, we will consider other NHSBT centres and ask that you raise any requests at interview.
Main duties of the job
This role will oversee the development and delivery of a broad and evolving portfolio of Advanced Cell Therapies across multiple Advanced Cell Therapy Units, always meeting challenging customer and regulatory requirements. Your responsibilities include:
Taking national responsibility for the delivery of advanced cell therapy manufacturing across multiple sites in line with agreed business objectives and regulatory requirements. Working with regional team Heads and quality assurance colleagues to navigate the interface between quality assurance and science and technology whilst maintaining close interactions with external customers and partners. Supporting and delivering operational strategies which build on CMTs core competencies to position NHSBT as a provider of choice for advanced cell therapies to UK and international customers. Providing scientific and regulatory knowledge to help continuously develop CMTs workforce, ensuring NHSBT is at the cutting edge of technological innovation. Developing strong credible relationships with key stakeholders including academic, commercial, NHS, regulatory and grant-awarding organisations. Working closely with the Heads of Cell Therapy Units, the Head of CBC (Molecular Therapies), the National Operations Manager and the Head of Business Development to deliver agreed projects on time and in budget.
About us
At NHS Blood and Transplant, were incredibly proud of the many talented people who come together every day to make our organisation the very best it can be. We have clearly defined values that are centred around offering exceptional care to our donors and their families. We take care of each other too and we focus on building our expertise so we can change lives, provide quality support and offer fulfilling careers.Its an opportunity to contribute to a unique team as part of a service that saves lives 365 days a year. We offer brilliant benefits including 27 days of holiday (plus bank holidays), a comprehensive induction and training programme, and competitive pension scheme.
We are passionate about creating an inclusive workplace and aim to reflect the diverse communities we work with and positively encourage applications from all sectors of the community.Three small words, one big difference - Caring, Expert and Quality.Together we'll save and improve more lives than ever
Job description
Job responsibilities
Please view the attached recruitment profile which is a summary of the detailed Job Description and Person Specification for the full personal attributes we require for the role. You will need to demonstrate these throughout the recruitment process.
This vacancy will close at 23:59 on Sunday 21st July 2024.
Interviews are anticipated to be held 15th Aug 2024 – subject to confirmation.
For informal enquiries please contact – Jon Smythe , Assistant Director of Cellular and Molecular Therapies at .
Person Specification
Qualifications
Essential
PhD in a field relevant to cell and gene therapies. Demonstrates commitment to own continued professional development (CPD).
Experience
Essential
Extensive experience in developing and manufacturing MHRA regulated cell and or gene-based therapies. Comprehensive understanding of relevant policies and standards , MHRA Good Manufacturing Practice, HTA TQSR and other relevant or statutory guidelines. Management experience in a relevant laboratory or operational environment. Experience of managing workload and staff to ensure effective service provision, including experience of target setting and performance review. Experience of selection, training, development, and motivation of staff. In depth knowledge of Cell and Gene Therapy Science. Demonstrable leadership and management skills. Understanding detailed budget management. Experience of working with Information Technology using Microsoft Office packages (Word, Excel and PowerPoint).