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Lead Scientist in Cell Therapy Manufacturing

2 months ago

London, Greater London, United Kingdom Northreach Full time
Position Overview

Job Title: Lead Scientist - Cell Therapy Manufacturing

Job Type: Full-Time

Northreach is a forward-thinking recruitment agency dedicated to linking organizations with exceptional talent in the Advanced Therapies domain. Our goal is to deliver a smooth and tailored recruitment journey for both clients and candidates, fostering a workplace that champions equality, innovation, and professional development.

About the Company:

Our client is an innovative biotechnology firm leading the way in cell-based treatment solutions. We are in search of a highly qualified and seasoned Lead Scientist to become a vital part of our MSAT team. This position presents a remarkable opportunity to play a key role in the progression of state-of-the-art T cell therapies aimed at addressing critical health issues.

Key Responsibilities:

  • Deliver project oversight and technical guidance to production teams, acting as the steward of the manufacturing process.
  • Facilitate development, technology transfer, and validation initiatives, ensuring effective collaboration through clear communication, scientific insight, and a focus on priorities and details.
  • Build strong relationships and collaborate with cross-functional partners (Project Management, Quality Control, Quality Assurance, Supply Chain, Production, Analytical Development, Process Development, and Regulatory Affairs) to support technology transfers and process performance qualification campaigns.
  • Drive the creation of processes and systems for data management, analysis, and trending.
  • Identify opportunities for ongoing enhancement of manufacturing processes through trend analysis, advancements in manufacturing technologies, and adherence to new industry standards.
  • Engage and present as a key project member in internal or external initiatives as a technical expert in drug product MSAT.
  • Verify equipment qualification as part of the process validation framework (e.g., correct installation, efficient operation, robust performance).
  • Establish training programs, mentor, and coach technical and production staff to cultivate high-performing technical operations and MSAT teams.
  • Actively participate in the evaluation of deviations, root cause analysis, corrective and preventive actions (CAPA), and change control processes with a strong emphasis on quality, risk management, and regulatory compliance.

Qualifications:

  • In-depth knowledge of immunology and cell therapy.
  • Proven expertise in cell-based methodologies, including cell enrichment, culture, and formulation technologies.
  • Ability to lead and manage a team while working independently and collaboratively with cross-functional teams across various locations.
  • Resourceful in addressing challenges and capable of thriving in a dynamic environment.
  • Experience collaborating closely with production teams, leading root cause investigations, and evaluating non-product quality impacting deviations.
  • Responsible for authoring and reviewing batch records, bills of materials, and change controls, assessing the impact of any changes to processes, equipment, or procedures.
  • Solid understanding of quality management systems.
  • Familiarity with technology transfer and collaboration with contract development and manufacturing organizations is advantageous.
  • Training in Six Sigma and/or manufacturing excellence methodologies is a plus.

Technical Skills:

  • Exceptional time and project management capabilities.
  • Minimum MSc in a relevant field with at least 4 years of experience in industry and/or academia.
  • Demonstrated commitment to high-quality work and maintaining rigorous standards.
  • Contribute to a culture that values scientific excellence, integrity, urgency, patient focus, and continuous improvement.
  • Experience in cGMP development and/or cell therapy product manufacturing is highly desirable.

Personal Attributes:

  • Ability to work collaboratively within a team, supporting each other and being accountable for project outcomes.
  • Strong personal drive and goal orientation.
  • Detail-oriented and precise.
  • Professional and approachable communication skills.
  • Motivated to solve problems in a practical manner.
  • Exhibits strong organizational and prioritization skills to manage a diverse workload.
  • Demonstrates a positive work attitude, reliability, and adaptability.
  • Willingness to work across multiple locations.

Compensation and Benefits:

We offer a competitive salary package commensurate with experience, along with comprehensive benefits including medical, dental, and vision coverage, retirement plans, and opportunities for professional advancement within a rapidly evolving field.

Northreach is an equal opportunity employer committed to fostering diversity, equity, and inclusion in the workplace. We strive to create a welcoming and inclusive environment for all employees.