Protein Biochemist

2 weeks ago


London, Greater London, United Kingdom Planet Pharma Full time
Job Opportunity

We are seeking a highly skilled Protein Biochemist to join our team at Planet Pharma. As a key member of our protein group, you will be responsible for the expression and purification of recombinant proteins, including multi-pass membrane proteins, for structural studies.

Key Responsibilities


• Lead the expression and purification of recombinant proteins, including multi-pass membrane proteins, using various techniques such as affinity chromatography, ion exchange, and SEC.


• Collaborate with project teams, enzymologists, crystallographers, and CADD groups to ensure effective communication and progress.


• Stay up-to-date with technology developments in protein expression and purification, particularly in the production of recombinant proteins, including multi-pass membrane proteins.

Requirements

Candidates should have a strong background in protein biochemistry and experience in protein expression and purification. A PhD or highly experienced Bachelor/MSc degree holder is preferred. We are looking for individuals with excellent written and verbal communication skills and a comprehensive knowledge of software used in manipulating protein and DNA sequences.


• Familiarity with insect and mammalian cell expression systems.


• Expertise in purification techniques, including affinity chromatography, ion exchange, and SEC.


• Proficiency in AKTA purification platforms and associated software.


• Strong knowledge of software used in manipulating protein and DNA sequences, such as VNTI, and molecular visualization tools like PyMOL.


• Excellent knowledge of the literature around the generation of recombinant proteins, including multi-pass membrane proteins, for structural studies.



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