Proteomics Expert

24 hours ago


London, Greater London, United Kingdom The Francis Crick Institute Full time
About the Role

We are seeking a highly skilled Senior Laboratory Research Scientist to join our Proteomics Scientific Technology Platform at the Francis Crick Institute. This is an exciting opportunity for a talented and experienced individual to contribute to cutting-edge proteomic research.

Job Description

The successful candidate will be responsible for driving forward qualitative and quantitative proteomic projects, from experimental design through sample preparation to data analysis. You will have hands-on experience of working in a mass spectrometry laboratory, including basic and advanced proteomic sample handling and processing protocols.

You will also be expected to develop, optimize and apply next-generation proteomics and mass spectrometry methods, such as DIA, DDA, label free profiling, TMT, PRM etc. Excellent communication, record keeping, time management and problem-solving skills are essential for this role.

Key Responsibilities:

  • Planning of experiments, decision making about which pipeline to take, and independently executing experiments for projects.
  • Performing both standard and bespoke proteomics experiments starting with sample preparation from a variety of biological sources using common biochemical methodologies.
  • Liquid chromatography tandem mass spectrometry (LC-MS/MS) nanoUHPLC data acquisition, evaluation, and processing of raw data.
  • Communication of results in collaboration.

Requirements:

  • PhD or equivalent experience gained through working in a mass spectrometry laboratory.
  • Direct experience with either the Thermo Scientific Orbitrap Tribrid platform or the Bruker timsTOF Ultra/Pro2.
  • Detailed understanding of proteomics related bioinformatics and associated software packages.
  • Experience with developing, optimizing and applying next-generation proteomics and mass spectrometry methods.

Salary: £60,000 - £70,000 per annum, depending on experience. We offer a comprehensive benefits package, including pension scheme, life insurance and annual leave.


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