Biomedical Mass Spectrometry Expert
1 day ago
B biomedical Mass Spectrometry Expert
About the Role:We are seeking a highly skilled and experienced Biomedical Mass Spectrometry Expert to join our team at The Francis Crick Institute. As a key member of our Proteomics Scientific Technology Platform (STP), you will play a crucial role in driving forward qualitative and quantitative proteomic and clinical proteomic projects, from experimental design through sample preparation to data analysis.
This is an excellent opportunity for a talented and motivated individual to contribute to our mission of discovery without boundaries. You will be part of a dynamic and collaborative environment, working closely with researchers, clinicians, and scientists from various disciplines to advance our understanding of human disease and develop innovative treatments.
About the Team:The Francis Crick Institute is a world-leading research organisation that brings together expertise in biology, physics, chemistry, medicine, engineering, and computer science to understand human health and disease. Our STP provides access to cutting-edge instrumentation and expertise across the range of applications necessary for modern biomedical research, including proteomics.
Key Responsibilities:- Planning of experiments, decision making about which pipeline to take, and independently executing experiments for projects.
- Performing both standard and bespoke proteomics experiments starting with sample preparation from a variety of biological sources using common biochemical methodologies for cell lysis, SDS-PAGE, in-gel, in-solution, TCA and acetone precipitation digest protocols, TMT labelling, high pH chromatographic fractionation and label free quantification.
- LC-MS/MS nanoUHPLC data acquisition, evaluation, and processing of raw data.
- A PhD or equivalent experience gained through working in a mass spectrometry laboratory, including basic and advanced proteomic sample handling and processing protocols, and familiarity with instrument maintenance requirements.
- Direct experience with either the Thermo Scientific Orbitrap Tribrid platform or the Bruker timsTOF Ultra/Pro2.
- Detailed understanding of proteomics related bioinformatics and associated software packages such as PEAKS, Mascot, Scaffold, MaxQuant, Spectronaut, DIA-NN and Skyline.
We offer a competitive salary of £60,000 - £70,000 per annum, depending on experience, plus benefits including pension scheme, annual leave, and training opportunities. We also provide a supportive and inclusive work environment, with a strong focus on career development and progression.
Contact Information:-
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