Mass Spec Operator

2 days ago

Harrogate, North Yorkshire, United Kingdom HAR Labcorp Early Development Laboratories Limited Full time
About HAR Labcorp Early Development Laboratories Limited

We are a leading contract research organization providing comprehensive drug development solutions for a range of industries. Our global expertise in nonclinical safety assessment, clinical trial testing, and clinical trial management services supports the development of innovative, life-changing treatments.

Position Overview

We are currently recruiting for a Mass Spec Operator to join the Bioanalysis department on a full-time basis. The successful candidate will operate the liquid chromatography-mass spectrometry (LC-MS) systems and provide a trouble-shooting resource for problematic LC-MS methods.

Key Responsibilities
  • Demonstrate a knowledge and commitment to health and safety procedures and practice, particularly the use of personal protection equipment and COSHH initiatives.
  • Conduct all work in compliance with applicable regulatory requirements.
  • Develop and maintain knowledge of current GLP and GCP regulations as applicable.
  • Ensure that all study-based activities are performed in accordance with the study protocol and Covance standard operating procedures (SOP) to the required scientific and regulatory standards.
  • Use data systems - Nautilus, Analyst, Watson, eWorkBook etc.
  • Communicate effectively with Laboratory Supervisors, Study Directors, Study Coordinators, and other members of staff within the department and from other departments.
Specific Tasks
  • Set-up and operation of LC-MS/MS instrumentation.
  • Run batches of samples on the LC-MS/MS systems as scheduled, verifying system suitability before analysis and completing post-analysis activities.
  • Provide cover for operation of LC-MS/MS equipment outside of usual core hours, as required.
  • Develop and implement new LC-MS/MS methods, as required, under the direction of the Method Development Manager/Method Development Specialist.
  • Complete required documentation (e.g., maintenance, metrology) in a timely fashion.
  • Ensure the cleanliness and tidiness of the MS laboratory at all times.
  • Develop knowledge in all aspects of bioanalysis and LC-MS/MS, remaining abreast of new skills, techniques, and regulatory requirements.
  • Maintain the instrument daily batch analysis schedule.
  • Liaise with external instrument maintenance/repair personnel, including preventative maintenance schedules.
Key Qualifications
  • Previous practical laboratory experience - minimum of 1 year in the operation of LC-MS/MS instruments.
  • Good communication skills and an understanding of Health & Safety policies, Company Policies and Procedures, and Good Laboratory Practice.
  • Computing skills, word processing, and use of spreadsheets required.
  • Appropriate academic qualifications: e.g., a degree in chemistry or a related subject.

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