Lead Clinical Scientist in Transplantation
3 weeks ago
Position Overview
Are you a seasoned HCPC registered Clinical Scientist specializing in Histocompatibility and Immunogenetics seeking a new opportunity?
Do you possess a strong interest in Molecular HLA typing?
We are looking for a knowledgeable and motivated Clinical Scientist to become the Head of the DNA section within our Clinical Transplantation Laboratory. The successful applicant will be required to maintain HCPC Registration as a Clinical Scientist in Histocompatibility and Immunogenetics, along with extensive experience in molecular typing techniques and team leadership.
Key Responsibilities
Our Clinical Transplantation Laboratory is accredited to both ISO 15189 and EFI standards, and is among the leading laboratories in the UK for solid organ transplantation, having supported numerous transplant procedures in the past year and currently expanding our services. We deliver a comprehensive H&I service to various adult and pediatric transplant centers, covering a range of transplant programs including renal, pancreas, cardiothoracic, islet, liver, and multi-visceral transplants. As a referral center for both national and international cases, we collaborate closely with transplant teams to provide expert advice on complex transplant scenarios, including ABO and HLA antibody incompatible transplants. Additionally, we conduct HLA and disease association testing and support various research initiatives.
The laboratory employs a variety of PCR-based methods for HLA genotyping, including NGS, SSOP, qPCR, and SSP. We utilize Luminex and flow cytometric techniques for antibody analysis and patient crossmatching, supported by a specialized Laboratory Information Management System (LIMS) and a Quality Management System (QMS).
About Our Organization
Our department operates from Monday to Friday, with core hours from 9 AM to 5 PM, and also provides a 24/7 on-call service. The successful candidate will be expected to work a full-time schedule and, once adequately trained, participate in the on-call service, which currently operates on a 1 in 7 rotation across two schedules.
Joining our team means becoming part of a small, friendly, and dedicated group of scientists working in a specialized area of pathology. We offer training and development opportunities through our Scientific Learning and Development fund and Continuing Professional Development (CPD) activities, including funding for various qualifications and conference attendance. We are also recognized as a training laboratory for several schemes and can support higher training for suitable candidates.
Professional Development
Our organization provides numerous learning opportunities through our Development program, the Scientific Learning and Development Fund, and the Synnovis Academy, which offers funding and support for advanced qualifications. Through our Innovation Accelerator Fund, you can seek financial support for innovative scientific projects. Opportunities to engage with the broader scientific community through symposiums, conferences, and peer group meetings are also available.
Job Duties
Clinical Responsibilities
- Engage at a senior level in all laboratory operations, including sample receipt, testing, result interpretation, quality management, audit, and staff training.
- Oversee and manage the workflow in the DNA section, ensuring a high-quality service is consistently delivered.
- Organize and allocate tasks for the Biomedical Scientists and Clinical Scientists, ensuring adequate backup for laboratory services.
- Take responsibility for the identification of Class I and II alleles using molecular methods.
- Verify the accuracy and interpretation of results generated by laboratory colleagues, adhering to national professional guidelines.
- Maintain comprehensive and accurate records of all laboratory activities.
- Ensure timely reporting of results and assist in the preparation of final reports as needed.
- Participate in the on-call rota as required, taking responsibility for unsupervised work and reporting results outside normal hours.
- Respond to inquiries from service users, providing guidance on available tests and sample requirements.
- Collaborate with other tissue typing laboratories for data and sample sharing when necessary.
Scientific Expertise
- Deliver a high level of laboratory skills and scientific knowledge in tissue typing.
- Assist with troubleshooting and maintain up-to-date Standard Operating Procedures.
- Conduct audits and monitor quality control exercises to enhance the accuracy and efficiency of molecular tests.
- Stay informed about current literature and developments in the field, introducing new techniques and equipment as appropriate.
- Represent the laboratory at various meetings, seminars, and conferences.
- Ensure the DNA service remains aligned with published research and present findings at relevant events.
Management and Administration
- Contribute to the development of new methodologies and evaluation of equipment.
- Assist in implementing laboratory objectives and strategies.
- Support staff recruitment and retention efforts.
- Manage funding activities and procurement authorizations.
- Advise on capital equipment purchases and maintain supplier relationships.
- Ensure compliance with Health and Safety regulations.
- Collaborate with senior staff to monitor workload and maintain service quality.
Research and Development
- Initiate and maintain research interests, actively participating in ongoing projects.
- Promote research in HLA, including Molecular Genetics and disease associations.
- Encourage collaborative studies with other departments and institutions.
- Present research findings at conferences and contribute to audits.
- Supervise research projects undertaken by staff members.
Teaching and Training
- Provide training in tissue typing and molecular methods to laboratory staff and visiting researchers.
- Assist in delivering educational services to clinicians and trainees.
- Ensure all staff maintain the necessary training and competence levels.
- Participate in educational courses and deliver lectures at scientific conferences.
- Engage in Continuing Professional Development and annual performance reviews.
Additional Responsibilities
- Oversee the daily operations of the DNA service.
- Perform basic laboratory duties as needed.
- Maintain high standards of scientific practice and documentation.
- Ensure regular servicing and maintenance of laboratory equipment.
- Adhere to departmental Health and Safety regulations.
- Manage departmental resources efficiently.
- Assist in stock control and procurement of laboratory supplies.
Synnovis Analytics is a partnership dedicated to delivering and transforming pathology services, providing diagnostics and testing for healthcare providers.
We are committed to equality of opportunity and welcome applications from all individuals, regardless of background or identity.
Our employees enjoy a competitive benefits package, including a contributory pension scheme, generous annual leave, and groundbreaking personal development opportunities.
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