Protein Design Specialist
2 months ago
Job Summary
We are seeking an experienced Computational Protein Design specialist to join our Antigen Design team at Baseimmune. The ideal candidate will have a proven track record in using deep learning methodologies, including generative AI, to design de novo protein structures.
Key Responsibilities
- Scientific Goals
- Drive the development of computational pipelines that use AI techniques to create proteins for use as vaccine antigens.
- Collaborate with laboratory teams to validate and benchmark newly implemented methodologies using in silico, in vitro and in vivo models.
- Apply computational based pipelines and structural expertise to design proteins presenting target epitopes in desired conformations.
- Collaborate effectively across multi-disciplinary teams, including immunologists, evolutionary biologists, molecular biologists and ML engineers to ensure de novo designs are optimised to elicit cross-protective responses following vaccination. Analyse and interpret experimental data to advance the design process.
- Strategic Goals
- Stay up to date with the latest research and developments within the field.
- Contribute to scientific publications and represent Baseimmune at scientific conferences.
- Minimum of 4 years' experience in computational protein design within an academic or industry setting.
- Extensive knowledge of statistical and deep learning methods applied to protein design, such as RFdiffusion, MPNN, AlphaFold and Rosetta.
- Experienced programming in Python and Linux command line.
- Proven track record of scientific innovation and publications in reputable journals.
What We Offer
- Private medical health insurance.
- Opportunities for career growth and professional development.
- 26 days holiday leave + bank holidays.
- Pension plan.
-
London, Greater London, United Kingdom Baseimmune Full timeAbout the RoleWe are seeking an experienced Computational Protein Design specialist to join our Antigen Design team at Baseimmune, a discovery stage biotechnology start-up revolutionising vaccines through advanced computational antigen design.As a key member of our team, you will be responsible for driving the development of computational pipelines that use...
-
London, Greater London, United Kingdom Baseimmune Full timeAbout the RoleWe are seeking an experienced Computational Protein Design specialist to join our Antigen Design team at Baseimmune, a discovery stage biotechnology start-up revolutionising vaccines through advanced computational antigen design.As a key member of our team, you will be responsible for driving the development of computational pipelines that use...
-
London, Greater London, United Kingdom Baseimmune Full timeJob DescriptionCompany OverviewBaseimmune is a pioneering biotechnology start-up revolutionizing vaccines through cutting-edge computational antigen design. Founded by the team that pioneered computational vaccines at the University of Oxford, our mission is to harness the fields of data science, machine learning, and computational biology to redefine...
-
London, Greater London, United Kingdom Baseimmune Full timeJob DescriptionCompany OverviewBaseimmune is a pioneering biotechnology start-up revolutionizing vaccines through cutting-edge computational antigen design. Founded by the team that pioneered computational vaccines at the University of Oxford, our mission is to harness the fields of data science, machine learning, and computational biology to redefine...
-
De Novo Metalloenzyme Design Specialist
1 week ago
London, Greater London, United Kingdom University of Bristol Full timeThe roleA postdoctoral position is available in the protein design laboratory of Prof Dek Woolfson at the University of Bristol to develop new metalloprotein scaffolds and elaborate these into de novo enzymes. The appointed post-doc would design de novo metalloenzymes based on new alpha-helical barrel proteins using computational design, and protein...
-
London, Greater London, United Kingdom University of Bristol Full timeA postdoctoral research position is available in the Protein Design Laboratory of Prof Dek Woolfson at the University of Bristol to develop new metalloprotein scaffolds and elaborate these into de novo enzymes.The appointed post-doc would design de novo metalloenzymes based on new alpha-helical barrel proteins using computational design, and protein...
-
London, Greater London, United Kingdom University of Bristol Full timeJob OpportunityA postdoctoral research position is available in the Protein Design Laboratory of Prof Dek Woolfson at the University of Bristol. The successful candidate will work on developing new metalloprotein scaffolds and elaborating these into de novo enzymes.Key ResponsibilitiesDesign and engineer de novo metalloenzymes based on new alpha-helical...
-
Senior Computational Biologist
1 month ago
London, Greater London, United Kingdom Baseimmune Full timeSenior Computational Biologist: Protein DesignWe are seeking an experienced Computational Protein Design specialist to join our Antigen Design team at Baseimmune. The ideal candidate will have a proven track record in using deep learning methodologies, including generative AI, to design de novo protein structures.Key Responsibilities:Drive the development of...
-
Senior Computational Biologist
1 month ago
London, Greater London, United Kingdom Baseimmune Full timeSenior Computational Biologist: Protein DesignWe are seeking an experienced Computational Protein Design specialist to join our Antigen Design team at Baseimmune. The ideal candidate will have a proven track record in using deep learning methodologies, including generative AI, to design de novo protein structures.Key Responsibilities:Drive the development of...
-
Scientific Researcher
2 weeks ago
London, Greater London, United Kingdom Hyper Recruitment Solutions Ltd Full timeWe are seeking a skilled Protein Expression & Purification Specialist to contribute to exciting drug discovery projects at a leading biotechnology company in the Cambridge area.Key Responsibilities:Develop and implement protein expression and purification strategies to support drug discovery projects.Collaborate with cross-functional teams to design and...
-
Urban Design Specialist
2 months ago
London, Greater London, United Kingdom Urban Design Group Full timeAbout the RoleWe are seeking a highly skilled and motivated individual to join our team as a Conservation and Urban Design Officer. As a key member of our Conservation, Heritage and Design Team, you will play a crucial role in providing specialist advice and guidance on the historic built environment and urban design matters.Key ResponsibilitiesProvide...
-
Urban Design Specialist
2 months ago
London, Greater London, United Kingdom Urban Design Group Full timeAbout the RoleWe are seeking a highly skilled and motivated individual to join our team as a Conservation and Urban Design Officer. As a key member of our Conservation, Heritage and Design Team, you will play a crucial role in providing specialist advice and guidance on the historic built environment and urban design matters.Key ResponsibilitiesProvide...
-
Senior Computational Biologist
1 month ago
London, Greater London, United Kingdom Baseimmune Full timeSenior Computational Biologist: Protein DesignWe are seeking an experienced Computational Protein Design specialist to join our Antigen Design team at Baseimmune, a discovery stage biotechnology start-up revolutionising vaccines through advanced computational antigen design.Key Responsibilities:Drive the development of computational pipelines that use AI...
-
Senior Computational Biologist
1 month ago
London, Greater London, United Kingdom Baseimmune Full timeSenior Computational Biologist: Protein DesignWe are seeking an experienced Computational Protein Design specialist to join our Antigen Design team at Baseimmune, a discovery stage biotechnology start-up revolutionising vaccines through advanced computational antigen design.Key Responsibilities:Drive the development of computational pipelines that use AI...
-
Urban Designer Specialist
2 days ago
London, Greater London, United Kingdom Urban Design Group Full timeAbout the Role:We are seeking an experienced Urban Designer to join our team in Bristol and Devon. As an Urban Designer Specialist, you will be responsible for designing and managing projects, including residential led developments and masterplanning. Your expertise will help us deliver integrated and sustainable solutions that meet the needs of our...
-
Urban Design Specialist
3 weeks ago
London, Greater London, United Kingdom Urban Design Group Full timeJob Title: Conservation and Urban Design OfficerAn exciting opportunity has arisen within the Conservation, Heritage and Design Team for a dynamic and committed individual to support the Council's professional Conservation, Heritage and Design advice service.Key Responsibilities:Provide specialist advice on built heritage and urban design matters to the...
-
Urban Design Specialist
3 weeks ago
London, Greater London, United Kingdom Urban Design Group Full timeJob Title: Conservation and Urban Design OfficerAn exciting opportunity has arisen within the Conservation, Heritage and Design Team for a dynamic and committed individual to support the Council's professional Conservation, Heritage and Design advice service.Key Responsibilities:Provide specialist advice on built heritage and urban design matters to the...
-
Urban Design Specialist
4 weeks ago
London, Greater London, United Kingdom Urban Design Group Full timeJob Title: Conservation and Urban Design OfficerAn exciting opportunity has arisen within the Conservation, Heritage and Design Team for a dynamic and committed individual to support the Council's professional Conservation, Heritage and Design advice service.Job Summary:The successful candidate will provide specialist advice on built heritage and urban...
-
Urban Design Specialist
4 weeks ago
London, Greater London, United Kingdom Urban Design Group Full timeJob Title: Conservation and Urban Design OfficerAn exciting opportunity has arisen within the Conservation, Heritage and Design Team for a dynamic and committed individual to support the Council's professional Conservation, Heritage and Design advice service.Job Summary:The successful candidate will provide specialist advice on built heritage and urban...
-
Creative Design Specialist
2 weeks ago
London, Greater London, United Kingdom James Glancy Design Full timeJob Title: Creative Design SpecialistWe are seeking a highly skilled and ambitious designer to join our team at James Glancy Design. As a Creative Design Specialist, you will be responsible for developing imaginative and impactful designs for a variety of public-realm activations.Key Responsibilities:Support the Senior Creative Designer with design...
