Research Fellow

2 weeks ago

London, United Kingdom University College London Full time

**Ref Number**

B02-06731

**Professional Expertise**

Research and Research Support

**Department**

School of Life & Medical Sciences (B02)

**Location**

London

**Working Pattern**

Full time

**Salary**

See advert text

**Contract Type**

Fixed-term

**Working Type**

On site

**Available For Secondment**

No

**Closing Date**

24-Apr-2024

**About us**:
The Department of Neuromuscular Diseases is a hub for clinical and research excellence across the spectrum of spinal cord and neuromuscular diseases. Our group of world-leading clinical, genetic and basic science researchers focus their work on understanding the causes and biological mechanisms leading to Neuromuscular Disease and translating this knowledge into developing novel therapeutic solutions that is of direct benefit to neurological disorders such as motor neurone disease, Alzheimer’s disease and neuromuscular disease.

The Patani Lab, based in the Department, aims to understand the molecular and cellular mechanisms underpinning motor neuron disease (ALS). We use a variety of patient derived iPSC lines to investigate disease-related events at molecular level across different relevant cell types, including motor neurons, astrocytes and microglia.

**About the role**:
We are seeking a Research Fellow to join our established and dedicated team of researchers using human induced pluripotent stem cells to study Motor Neuron Disease (ALS).

Based in the laboratory of Professor Rickie Patani, you will be working on resolving the molecular basis of motor neuron degeneration with a particular focus on the relationship between genomic instability and aberrant RNA metabolism using established human stem cell models of ALS. You will utilise cutting-edge sequencing approaches, such as DRIP-seq, INDUCE-seq and bulk RNAseq (through a collaboration with the Boulton lab at the Francis Crick Institute) to explore the complex functional interaction between these processes.

This is a compelling opportunity to contribute to ground-breaking, high-impact research projects within an intellectually stimulating, globally diverse scientific community.

The role is available immediately and funded by My Name’5 Doddie Foundation for two years in the first instance.

A full job description and person specification for this role can be accessed below.

**About you**:
**What we offer**:
Starting salary offered in the rage £42,099 - £49,263 per annum.

Appointment as Research Fellow is dependent upon having been awarded a PhD; if this is not the case, initial appointment will be as Research Assistant (salary £37,332 - £39,980 per annum) with appointment as Research Fellow being backdated to the date of final submission of the PhD thesis.

As well as the exciting opportunities this role presents, we also offer great benefits, some of which are below:

- 41 Days holiday (27 days annual leave 8 bank holiday and 6 closure days)
- Additional 5 days’ annual leave purchase scheme
- Defined benefit career average revalued earnings pension scheme (CARE)
- Cycle to work scheme and season ticket loan
- Immigration loan
- Relocation scheme for certain posts
- On-site nursery
- On-site gym
- Enhanced maternity, paternity and adoption pay
- Employee assistance programme: Staff Support Service
- Discounted medical insurance

**Our commitment to Equality, Diversity and Inclusion**:
The Institute prides itself on operating in an all-inclusive environment irrespective of personal, physical, or social characteristics. Teamwork is highly valued, individual strengths are recognised and celebrated, and we are committed to advancing the careers of everyone. 12% of Institute staff are actively working on Equality, Diversity and Inclusion (EDI) initiatives; visit our EDI website for more information about our initiatives and priorities. The Institute also holds an Athena SWAN Silver award, in recognition of our commitment and demonstrable impact in advancing gender equality.

As London’s Global University, we know diversity fosters creativity and innovation, and we want our community to represent the diversity of the world’s talent. We are committed to equality of opportunity, to being fair and inclusive, and to being a place where we all belong.

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