Current jobs related to Computational Chemist - Cambridge - Next Phase Recruitment
-
Lead Computational Chemist
5 days ago
Cambridge, Cambridgeshire, United Kingdom CK Group Full timeJob SummaryWe are seeking an exceptional computational chemist and drug hunter to lead the Computational Chemistry team at CK Group. This is an exciting opportunity to leverage cutting-edge computational approaches in drug discovery projects and develop novel methodologies for wider utility.About the RoleAs Head of Computational Chemistry, you will manage a...
-
Computational Chemist
4 days ago
Cambridge, Cambridgeshire, United Kingdom Bicycle Therapeutics Full timeAbout the RoleBicycle Therapeutics is a clinical-stage biopharmaceutical company dedicated to developing innovative medicines for underserved diseases. We are seeking a highly skilled Computational Chemist to join our team and contribute to the development of our novel class of medicines, referred to as Bicycle molecules.Key ResponsibilitiesProvide...
-
Computational Chemist
4 days ago
Cambridge, Cambridgeshire, United Kingdom Bicycle Therapeutics Full timeAbout Bicycle TherapeuticsBicycle Therapeutics is a clinical-stage biopharmaceutical company dedicated to developing innovative medicines for underserved diseases. Our proprietary technology enables the creation of high-affinity and selective molecules, making us an attractive partner for drug development.Job SummaryWe are seeking a highly skilled...
-
Computational Chemist
1 day ago
Cambridge, Cambridgeshire, United Kingdom Bicycle Therapeutics Full timeAbout Bicycle TherapeuticsBicycle Therapeutics is a clinical-stage biopharmaceutical company dedicated to developing innovative medicines for underserved diseases. Our proprietary technology enables the creation of high-affinity and selective molecules, making us an attractive partner for drug development.Job SummaryWe are seeking a highly skilled...
-
Computational Chemist
23 hours ago
Cambridge, Cambridgeshire, United Kingdom Bicycle Therapeutics Full timeAbout Bicycle TherapeuticsBicycle Therapeutics is a clinical-stage biopharmaceutical company dedicated to developing innovative medicines for underserved diseases. Our proprietary technology enables the creation of high-affinity and selective molecules, making us an attractive partner for drug development.Job SummaryWe are seeking a highly skilled...
-
Senior Computational Chemist and Leader
4 days ago
Cambridge, Cambridgeshire, United Kingdom CK Group Full timeJob DescriptionAbout CK GroupCK Group is a technology-driven biopharmaceutical company focused on developing innovative treatments for unmet medical needs. We are committed to leveraging cutting-edge computational approaches to drive our drug discovery efforts.Job SummaryWe are seeking an experienced computational chemist and leader to head our Computational...
-
Computational Chemist
4 weeks ago
Cambridge, United Kingdom Bicycle Therapeutics Full timeJob DescriptionWe are looking for a computational chemist with experience in various techniques including virtual screening, molecular dynamics and applying machine learning (ML) models to analyse and interpret a broad spectrum of project data.You will join a highly collaborative environment and work with multiple teams, both UK and US based, within our drug...
-
Senior Computational Chemist
24 hours ago
Cambridge, Cambridgeshire, United Kingdom Bicycle Therapeutics Full timeAbout the RoleWe are seeking a highly skilled Senior Computational Chemist to join our team at Bicycle Therapeutics, a clinical-stage biopharmaceutical company dedicated to developing innovative medicines for underserved diseases.Key ResponsibilitiesContribute to the development of computational chemistry technologies for drug discovery, including virtual...
-
Senior Computational Chemist
1 day ago
Cambridge, Cambridgeshire, United Kingdom Bicycle Therapeutics Full timeAbout the RoleWe are seeking a highly skilled Senior Computational Chemist to join our team at Bicycle Therapeutics, a clinical-stage biopharmaceutical company dedicated to developing innovative medicines for underserved diseases.Key ResponsibilitiesContribute to the development of computational chemistry technologies for drug discovery, including virtual...
-
Senior Computational Chemist
4 days ago
Cambridge, Cambridgeshire, United Kingdom Bicycle Therapeutics Full timeJob DescriptionBicycle Therapeutics is a biopharmaceutical company dedicated to developing innovative medicines for underserved diseases. We are seeking a highly skilled Senior Computational Chemist to join our team and contribute to the development of our novel class of medicines.Key Responsibilities:Provide computational chemistry expertise to support drug...
-
Computational Chemist
4 days ago
Cambridge, United Kingdom Bicycle Therapeutics Full timeBicycle Therapeutics is a clinical-stage biopharmaceutical company developing a novel class of medicines, referred to as Bicycle® molecules, for diseases that are underserved by existing therapeutics. Bicycle molecules are fully synthetic short peptides constrained with small molecule scaffolds to form two loops that stabilize their structural geometry....
-
Computational Chemist
6 days ago
Cambridge, United Kingdom Bicycle Therapeutics Full timeBicycle Therapeutics is a clinical-stage biopharmaceutical company developing a novel class of medicines, referred to as Bicycle® molecules, for diseases that are underserved by existing therapeutics. Bicycle molecules are fully synthetic short peptides constrained with small molecule scaffolds to form two loops that stabilize their structural geometry....
-
Computational Chemist
3 weeks ago
Cambridge, United Kingdom Bicycle Therapeutics Full timeBicycle Therapeutics is a clinical-stage biopharmaceutical company developing a novel class of medicines, referred to as Bicycle® molecules, for diseases that are underserved by existing therapeutics. Bicycle molecules are fully synthetic short peptides constrained with small molecule scaffolds to form two loops that stabilize their structural geometry....
-
Computational Chemist
3 days ago
Cambridge, United Kingdom Bicycle Therapeutics Full timeBicycle Therapeutics is a clinical-stage biopharmaceutical company developing a novel class of medicines, referred to as Bicycle® molecules, for diseases that are underserved by existing therapeutics. Bicycle molecules are fully synthetic short peptides constrained with small molecule scaffolds to form two loops that stabilize their structural geometry....
-
Computational Chemist
3 weeks ago
Cambridge, United Kingdom Bicycle Therapeutics Full timeBicycle Therapeutics is a clinical-stage biopharmaceutical company developing a novel class of medicines, referred to as Bicycle® molecules, for diseases that are underserved by existing therapeutics. Bicycle molecules are fully synthetic short peptides constrained with small molecule scaffolds to form two loops that stabilize their structural geometry....
-
Computational Chemist
17 hours ago
Cambridge, United Kingdom Bicycle Therapeutics Full timeBicycle Therapeutics is a clinical-stage biopharmaceutical company developing a novel class of medicines, referred to as Bicycle® molecules, for diseases that are underserved by existing therapeutics. Bicycle molecules are fully synthetic short peptides constrained with small molecule scaffolds to form two loops that stabilize their structural geometry....
-
Computational Chemist
1 week ago
Cambridge, United Kingdom Bicycle Therapeutics Full timeBicycle Therapeutics is a clinical-stage biopharmaceutical company developing a novel class of medicines, referred to as Bicycle® molecules, for diseases that are underserved by existing therapeutics. Bicycle molecules are fully synthetic short peptides constrained with small molecule scaffolds to form two loops that stabilize their structural geometry....
-
Computational Chemist
3 weeks ago
Cambridge, United Kingdom Bicycle Therapeutics Full timeBicycle Therapeutics is a clinical-stage biopharmaceutical company developing a novel class of medicines, referred to as Bicycle® molecules, for diseases that are underserved by existing therapeutics. Bicycle molecules are fully synthetic short peptides constrained with small molecule scaffolds to form two loops that stabilize their structural geometry....
-
Computational Chemist
4 weeks ago
Cambridge, United Kingdom Bicycle Therapeutics Full timeBicycle Therapeutics is a clinical-stage biopharmaceutical company developing a novel class of medicines, referred to as Bicycle® molecules, for diseases that are underserved by existing therapeutics. Bicycle molecules are fully synthetic short peptides constrained with small molecule scaffolds to form two loops that stabilize their structural geometry....
-
Senior Computational Chemist
3 weeks ago
Cambridge, Cambridgeshire, United Kingdom Bicycle Therapeutics Full timePosition OverviewWe are seeking a skilled computational chemist with a robust background in various methodologies, including virtual screening, molecular dynamics, and the application of machine learning (ML) models to analyze and interpret diverse project data.This role offers an opportunity to work in a highly collaborative setting, engaging with multiple...
Computational Chemist
1 month ago
I am looking for a computational chemist with experience in various techniques including virtual screening, molecular dynamics, and applying machine learning (ML) models to analyse and interpret a broad spectrum of project data. This is for a clinical-stage biopharmaceutical company developing a novel class of medicines, for diseases that are underserved by existing therapeutics.
You will join a highly collaborative environment and work with multiple teams, both UK and US based, within their drug discovery pipeline. You will be highly-motivated, self-starting, and ambitious.
Key responsibilities
- You will be involved in multiple projects drawn from a range of therapeutic areas and at different stages from initial hit identification to lead optimisation
- Responsible for providing computational chemistry expertise to cross-functional teams to support drug discovery projects.
- Contribute to the ongoing development of computational chemistry technologies for drug discovery within the company
- Developing and implementing tools and workflows to extract, integrate, analyse and visualise chemical, biophysical and ADMET data to support our various project decision making processes
- Support and train members of the discovery teams in the use of analysis and visualisation tools and other aspects of computational chemistry
Qualifications
Essential:
- Industry experience, or post doctorial experience in computational chemistry
- Practical knowledge of conducting and analysis of molecular dynamics (MD) simulations using standard software such as OpenMM, AMBER and/or GROMACS, etc
- Experience in QSAR virtual screening, ideally with peptides
- Experience in writing analysis scripts and pipelines in common scripting languages, such as python, in Jupyter notebooks or as standalone scripts.
- Experience in amino acid and peptide modelling
- Practical knowledge of Free Energy Perturbation (FEP) calculations
- Use of HPC
Desirable:
- Knowledge of cheminformatics methods and databases
- Practical knowledge of quantum mechanical calculations (QM)
- Skills in machine learning, deep learning, statistical modelling, and advanced data analytics
- Experience in drug discovery organisation(s)
