Process Development Scientist
2 months ago
Our client, an establish privately owned biotech company that manufacture high purity biopharmaceutical products currently have an opportunity for a Senior Process Development Scientist to join their team. The role will be responsible for synthesising a range of peptides and peptide conjugates to support the polyclonal antibofy programme. The role will also co-ordinate the delivery of a variety of polyclonal antibody projects, through process development and technical transfer into the GMP production facility.
Responsibilities:
The main duties include:
Lead the synthesis and purification activities to produce high quality peptide products
Co-ordinate process development of polyclonal antibody projects (and project re-makes) to enable smooth transition into GMP production
Provide a high level of specialist technical knowledge and hands-on training
Prepare project specific development documentation to a high standard e.g. SOPs, development protocols and associated reports, batch records
Adhere to company Quality and Health and Safety Policies
Skills/Experience Required:
Essential:
Degree in relevant scientific discipline
Extensive hands-on bench experience in peptide synthesis, purification and analysis
Extensive experience in downstream processing and scale up, to include: column chromatography, Tangential Flow Filtration
Experience in protein analytical methods i.e. SDS-PAGE, protein assays, UV assays, HPLC
Competent in word processing, spreadsheet and database entry skills
Experience in writing technical documents, e.g. development reports, batch records, SOPs
Desirable
Use of PurePep Chorus Peptide Synthesiser
Experience in bioconjugation of peptide
Use of AKTA (or similar) system in protein purification and scale-up
Experience in technology transfer of products/processes
Knowledge of ELISA methodology for protein analysis
Personal Attributes:
Excellent oral and written communication skills
Excellent attention to detail
The ability to work independently and within a team environment
Ability to solve complex problems with focus on continuous improvement
Ability to adapt to rapidly changing demands
Please apply online in the first instance.
STEM Recruitment Solutions Ltd operates as a Recruitment Agency in this instance. We endeavour to reply to all applications when possible
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