Process Development Scientist

5 days ago

Bush Midlothian, United Kingdom Stem Recruitment Full time
Our client, an establish privately owned biotech company that manufacture high purity biopharmaceutical products currently have an opportunity for a Senior Process Development Scientist to join their team.  The role will be responsible for  synthesising a range of peptides and peptide conjugates to support the polyclonal antibofy programme.  The role will also co-ordinate the delivery of a variety of polyclonal antibody projects, through process development and technical transfer into the GMP production facility.
Responsibilities:
The main duties include:
Lead the synthesis and purification activities to produce high quality peptide products  

Co-ordinate process development of polyclonal antibody projects (and project re-makes) to enable smooth transition into GMP production

Provide a high level of specialist technical knowledge and hands-on training

Prepare project specific development documentation to a high standard e.g. SOPs, development protocols and associated reports, batch records

Adhere to company Quality and Health and Safety Policies
Skills/Experience Required:
Essential:
Degree in relevant scientific discipline

Extensive hands-on bench experience in peptide synthesis, purification and analysis

Extensive experience in downstream processing and scale up, to include: column chromatography, Tangential Flow Filtration

Experience in protein analytical methods i.e. SDS-PAGE, protein assays, UV assays, HPLC

Competent in word processing, spreadsheet and database entry skills

Experience in writing technical documents, e.g. development reports, batch records, SOPs
Desirable
Use of PurePep Chorus Peptide Synthesiser

Experience in bioconjugation of peptide

Use of AKTA (or similar) system in protein purification and scale-up

Experience in technology transfer of products/processes

Knowledge of ELISA methodology for protein analysis
Personal Attributes:
Excellent oral and written communication skills
Excellent attention to detail

The ability to work independently and within a team environment

Ability to solve complex problems with focus on continuous improvement

Ability to adapt to rapidly changing demands
Please apply online in the first instance.
STEM Recruitment Solutions Ltd operates as a Recruitment Agency in this instance.  We endeavour to reply to all applications when possible

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