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PhD Studentship Opportunity in piRNA-Guided Transposon Silencing

1 month ago


Cambridge, Cambridgeshire, United Kingdom Cancer Research UK Cambridge Institute Full time

Project Overview

Cancer Research UK Cambridge Institute is seeking a talented PhD student to join the interdisciplinary laboratory of Professor Greg Hannon, focusing on the piRNA pathway and its role in transposon silencing. This project aims to uncover the molecular mechanisms underlying piRNA-guided transposon control, using a combination of tissue culture and in vivo models.

Research Objectives

The successful candidate will exploit various biochemical, proteomic, imaging, genomics, and computational approaches to study piRNA-guided transposon control. This project is expected to contribute to our understanding of this fascinating small RNA pathway and discover fundamental biology with impacts on the RNA and chromatin biology fields.

Requirements

We are looking for an enthusiastic and competent student with excellent laboratory skills, a strong background in biochemistry, genetics, and/or molecular biology, as well as a keen interest in transposons, small RNAs, or chromatin biology. A reasonable amount of practical research experience and an eagerness to discover fundamental biology are essential. Familiarity with imaging approaches, genomics methods, or expertise with the Drosophila model would be beneficial but are not strictly required.

Funding and Eligibility

This four-year studentship is funded by Cancer Research UK Cambridge Institute and includes full funding for University fees and a stipend of £21,000 per annum for four years. We welcome applications from both UK and overseas students. Applicants with relevant research experience, gained through Master's study or while working in a laboratory, are strongly encouraged to apply.

How to Apply

Please apply via the University Applicant Portal. For further information about the course and to access the Applicant Portal, visit: https://www.postgraduate.study.cam.ac.uk/courses/directory/cvcrpdmsc You should select to commence study in Michaelmas Term 2025 (October 2025).