PhD Studentship Opportunity in RNA and Chromatin Biology

1 month ago


Cambridge, Cambridgeshire, United Kingdom University of Cambridge Full time

Project Overview

This PhD studentship is an exciting opportunity to join the interdisciplinary laboratory of Professor Greg Hannon at the Cancer Research UK Cambridge Institute, University of Cambridge. The project aims to uncover the molecular mechanisms that underlie the piRNA pathway, mainly using the fruit fly Drosophila melanogaster as a model.

Research Objectives

The successful candidate will exploit tissue culture as well as in vivo models, and carry out various biochemical, proteomic, imaging, genomics (including state-of-the-art RNA and chromatin profiling methods), and computational approaches to study piRNA-guided transposon control. This project is expected to contribute to our understanding of this fascinating small RNA pathway and discover fundamental biology with impacts on the RNA and chromatin biology fields.

Key Skills and Knowledge

We are looking to recruit an enthusiastic and competent student with excellent laboratory skills, a strong background in biochemistry, genetics and/or molecular biology, as well as a keen interest in transposons, small RNAs or chromatin biology. A reasonable amount of practical research experience (ideally exceeding 6 months) and an eagerness to discover fundamental biology is essential. Familiarity with imaging approaches, genomics methods or expertise with the Drosophila model would be beneficial but are not strictly required.

Funding and Eligibility

This four-year studentship is funded by Cancer Research UK Cambridge Institute and includes full funding for University fees and, in addition, a stipend currently of £21,000 per annum for four years. We welcome applications from both UK and overseas students. Applications are invited from recent graduates or final-year undergraduates who hold or expect to gain a First/Upper Second Class degree (or equivalent) in a relevant subject from any recognised university worldwide.



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