Bioinformatics Researcher Role

5 days ago

London, Greater London, United Kingdom Francis Crick Institute Full time

Job Description:

We are seeking a highly skilled Genomics Data Analyst to join our team at the Francis Crick Institute. This is a full-time, fixed-term position (4 years) on Crick terms and conditions of employment.

As a Genomics Data Analyst, you will work within the bioinformatics team of the Cancer Dynamics lab, collaborating with other groups at the Institute, academic, clinical and industry partners of MANIFEST.

The successful candidate will leverage data from the MANIFEST, TRACERx Renal, and PEACE studies to perform bioinformatics discovery analyses aimed at identifying genomic and transcriptomic features that influence responses and resistance to immunotherapy.

You will interact closely with the machine learning team that aims to integrate several features for building a robust model to predict response to immunotherapy.

Key Responsibilities:

  • Conduct analyses of genomic and transcriptomic data using established pipelines.
  • Analyse DNA sequencing data, identifying somatic mutations, copy number aberrations, and neoantigens.
  • Analyse RNA sequencing data, performing immune deconvolution and identifying gene expression signatures.
  • Evaluate and provide state-of-the-art tools, databases, protocols and methods necessary for the analysis of biological data.
  • Liaise and coordinate between project collaborators including clinicians, cancer biologists, machine learning experts and mathematical modellers.
  • Document all analyses in an accurate, timely and clearly presented manner, and use this to prepare data summaries and reports as required.

Benefits:

  • A competitive salary of £70,000 - £80,000 per annum.
  • A comprehensive benefits package, including access to a range of training and development opportunities.
  • A flexible working environment that supports work-life balance.

About Us:

The Francis Crick Institute is a world-leading biomedical research institute located in London. We conduct research at the forefront of biomedical science, combining rigour with an open and collaborative culture.

We have a wide research portfolio with no divisions or departments, bringing biomedical researchers together with clinicians, physical scientists and applied scientists from our pharmaceutical partners.

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