Senior Bioinformatics Lead

15 hours ago


London, Greater London, United Kingdom Northreach Full time
Northreach

We are seeking a highly skilled Senior Bioinformatician/Data Scientist to lead research and development efforts in gene-editing systems, mobile genetic elements, and metagenomic data projects. This role offers a unique opportunity to contribute to pioneering therapeutic discoveries in gene editing and microbial genomics.

About the Role

The successful candidate will be responsible for leading research and curation of novel gene-editing mechanisms beyond CRISPR screening, applying advanced bioinformatics methods to catalog and characterize diverse gene-editing systems for therapeutic potential.

Key Responsibilities:
  • Lead research and development of novel gene-editing systems beyond traditional CRISPR applications.
  • Apply advanced bioinformatics methods to identify, curate, and analyze MGEs and viral integration events within metagenomic datasets.
  • Develop methods to track and characterize these elements for genomic instability and therapeutic applications.
  • Conduct comprehensive analyses on large metagenomic and microbiome datasets using robust computational tools.
  • Generate insights into microbial ecology, gene function, and genomic context of therapeutic elements within microbial communities.
  • Drive research with a therapeutic focus, identifying gene-editing systems or MGEs for human health applications.
  • Collaborate with interdisciplinary teams to translate findings into viable therapeutic candidates.
Requirements
  • PhD or Master's in Bioinformatics, Computational Biology, Genomics, or related field with expertise in gene-editing systems, MGEs, or viral integration research.
  • Extensive experience in large-scale metagenomic or microbiome data analysis.
  • Proven background in developing bioinformatic methods or pipelines for discovery and curation of gene-editing systems beyond traditional CRISPR applications.
  • Knowledge of gene-editing therapeutic applications, MGE biology, and viral integration with interest in translational research.
  • Proficiency in bioinformatics programming languages (Python, R, or similar) and experience with large data management and workflow development.
Compensation Package

$140,000 - $160,000 per annum, depending on experience.



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