Scientist: Manufacturing Process Specialist

3 days ago

Sandwich, Kent, United Kingdom Asymchem Group Full time
Job Title: Scientist: Manufacturing Process Specialist

Asymchem Group is seeking a highly skilled Scientist: Manufacturing Process Specialist to join our team in the UK. As a key member of our process safety team, you will play a pivotal role in ensuring the safe scale-up of processes during laboratory studies and tech transfer to pilot plant and commercial facilities.

Key Responsibilities:
  • Apply process safety workflows in partnership with project teams during laboratory scale-up and scale-up into pilot plant facilities, ensuring appropriate recommendations are made.
  • Design, execute and interpret complex laboratory experiments to accurately assess the safety of starting materials, intermediates, reagents waste streams and chemical reactions prior to scale-up and help implement suitable mitigation measures.
  • Formulate clear, concise recommendations based on process safety testing results in detailed reports and oral representation.
  • Lead/contribute to the evaluation of novel technologies and techniques to maintain world-class process safety testing capabilities.
  • Maintain laboratory operations, proactively work with vendors/internal engineers to maintain equipment to a high standard and ensure optimal performance to mitigate downtime.
  • Identify initiatives to enhance process safety workflows and technology to improve process safety testing efficiency.
  • Establish networks and interfaces across the pharma/CDMO space and academia.
  • Act as a resource across the process safety network to give expert opinion and alternative insights on the interpretation of data to ensure effective assessment of chemical reaction hazards.
  • Work with external testing houses to identify and coordinate safety testing where required to generate data outside of internal capabilities and foster effective relationships.
  • Deliver process safety testing training to new starters and develop new training materials where required as the process safety function evolves.
Requirements:
  • BS/MS in chemistry or chemical engineering with a minimum 5 years (relevant API) experience in small molecule development.
  • Awareness and expertise in the various elements and concepts of process safety testing and inherently safer process design.
  • Hands-on experience operating and data interpretation from the following state-of-the-art process safety testing equipment: Differential Scanning Calorimetry, Thermal Screening Unit (or similar), Accelerating Rate Calorimetry, Mettler Toledo RC1.
  • Experience in writing process safety testing documents to support the safe scale-up of processes during laboratory studies and tech transfer to pilot plant and commercial facilities.
  • Active participant in process hazard analyses.
  • Ability to perform complex tasks such as handling large amounts of data and performing mathematical calculations.

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