PhD Researcher in Immune Hedgehog Signalling Dynamics

2 weeks ago


Cambridge, Cambridgeshire, United Kingdom University of Cambridge Full time

Project Overview

The University of Cambridge is seeking a highly motivated PhD researcher to join our team in the Cancer Research UK Cambridge Institute. The successful candidate will work on a project entitled "Immune Hedgehog signalling dynamics in health and disease" under the supervision of Dr Maike de la Roche.

Research Objectives

The project aims to shed light on the dynamics of Hedgehog signalling in immune cells using cutting-edge techniques such as chromobody technology, bespoke mouse models, and proximity labelling. The student will work with murine and human immune cells to gain fundamental mechanistic insight that may inform novel therapeutic entry points into cancer, infection, and autoimmunity.

Key Responsibilities

  • Conduct research in the field of immune Hedgehog signalling dynamics
  • Design and implement experiments using chromobody technology, bespoke mouse models, and proximity labelling
  • Collect and analyse data to gain mechanistic insight into Hedgehog signalling in immune cells
  • Present research findings at conferences and publish in peer-reviewed journals

Requirements

We welcome applications from recent graduates or final-year undergraduates who hold or expect to gain a First/Upper Second Class degree (or equivalent) in a relevant subject from any recognised university worldwide. The successful candidate will have a strong background in molecular biology, immunology, and/or cancer biology, and excellent communication and teamwork skills.

Funding

This four-year studentship is funded by Cancer Research UK Cambridge Institute and includes full funding for University fees and a stipend of £21,000 per annum for four years.

Eligibility

We welcome applications from both UK and overseas students. The University actively supports equality, diversity, and inclusion and encourages applications from all sections of society.



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