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PhD Studentship: Investigating piRNA-Mediated Transposon Silencing
1 month ago
Project Overview
The Cancer Research UK Cambridge Institute is seeking a highly motivated PhD student to join the interdisciplinary laboratory of Professor Greg Hannon. The successful candidate will work on a project entitled "Delineating piRNA-guided silencing of transposable elements".
This project aims to uncover the molecular mechanisms that underlie the piRNA pathway, mainly using the fruit fly Drosophila melanogaster as a model. The student will exploit tissue culture as well as in vivo models, and carry out various biochemical, proteomic, imaging, genomics, and computational approaches to study piRNA-guided transposon control.
The successful candidate will have excellent laboratory skills, a strong background in biochemistry, genetics, and/or molecular biology, and a keen interest in transposons, small RNAs, or chromatin biology. Familiarity with imaging approaches, genomics methods, or expertise with the Drosophila model would be beneficial but are not strictly required.
The studentship is funded by Cancer Research UK Cambridge Institute and includes full funding for University fees and a stipend of £21,000 per annum for four years. We welcome applications from both UK and overseas students.
Key Responsibilities
- Conduct research on piRNA-guided transposon control using Drosophila melanogaster as a model
- Develop and implement various biochemical, proteomic, imaging, genomics, and computational approaches to study piRNA-guided transposon control
- Collaborate with the interdisciplinary laboratory team to achieve project goals
- Present research findings at international conferences and publish in high-impact journals
Requirements
- PhD in a relevant field (biochemistry, genetics, molecular biology, etc.)
- Excellent laboratory skills and a strong background in biochemistry, genetics, and/or molecular biology
- Keen interest in transposons, small RNAs, or chromatin biology
- Familiarity with imaging approaches, genomics methods, or expertise with the Drosophila model would be beneficial but are not strictly required
How to Apply
To complete your online application, you will need to answer/provide the following:
- Choice of project and supervisor
- Course-specific questions
