PhD Studentship in Cancer Research: Modelling Therapeutic Approaches for Ovarian Cancer

3 weeks ago

Cambridge, Cambridgeshire, United Kingdom University of Cambridge Full time
Project Overview

The University of Cambridge is seeking a highly motivated PhD student to work on a project entitled "Modelling new therapeutic approaches for neoadjuvant treatment of high grade serous ovarian carcinoma". This project aims to develop new therapeutic strategies for ovarian cancer, with a focus on neoadjuvant treatment.

Research Objectives

The successful candidate will work on the following research objectives:

  • To develop new therapeutic approaches for ovarian cancer using integrative approaches, including genomic and functional characterization of clinical trial samples, patient-derived organoid and xenograft models, and whole genome sequencing methods.
  • To investigate the molecular mechanisms underlying ovarian cancer and identify potential therapeutic targets.
  • To design and conduct experiments to test the efficacy of new therapeutic approaches in preclinical models.
Methodology

The project will involve a combination of computational and experimental approaches, including:

  • Genomic and functional characterization of clinical trial samples and patient-derived organoid and xenograft models.
  • Whole genome sequencing and analysis of genomic data.
  • Design and conduct of experiments to test the efficacy of new therapeutic approaches in preclinical models.
Expected Outcomes

The successful candidate can expect to:

  • Develop innovative skills in both computational and experimental approaches.
  • Contribute to the development of new therapeutic strategies for ovarian cancer.
  • Publish research findings in high-impact scientific journals.
Requirements

To be eligible for this studentship, applicants must:

  • Hold or expect to gain a First/Upper Second Class degree (or equivalent) in a relevant subject from any recognised university worldwide.
  • Have a strong background in cancer biology, genomics, or a related field.
  • Have excellent communication and teamwork skills.
Funding

This four-year studentship is funded by Cancer Research UK Cambridge Institute and includes full funding for University fees and a stipend of £21,000 per annum for four years.

Eligibility

We welcome applications from both UK and overseas students.

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