Scientist Researcher

2 days ago

Great Abington, United Kingdom Cancer Research UK Full time
About Cancer Research UK

Cancer Research UK is a world-leading charity dedicated to beating cancer through research and innovation. Our mission is to bring forward the day when all cancers are conquered.

Job Summary

We are seeking an Associate Scientist to join our antibody discovery team, where you will play a key role in delivering therapeutic antibodies against a range of oncology targets. As an Associate Scientist, you will work closely with a multi-disciplinary team to generate antibody and antibody fragment reagents, perform purification, and maintain inventory.

Key Responsibilities
  • Generate antibody and antibody fragment reagents using bacterial and mammalian expression systems
  • Purify antibody and antigen proteins using AKTA and other automated purification platforms
  • Perform quality control using analytical techniques such as SDS-PAGE, HPLC, and Western blotting
  • Maintain inventory and support supply of candidates to the wider Antibody Discovery and Bioscience team
  • Undertake molecular biology tasks such as restriction digest and golden gate cloning
  • Maintain and operate state-of-the-art laboratory equipment
Requirements
  • Degree in a relevant field
  • Knowledge of current protein expression and purification methods
  • Knowledge of biochemical and/or cell-based assay systems
  • Knowledge of molecular biology techniques relevant to the construction of expression vectors for downstream screening of antibodies and antibody fragments
  • Experience in protein purification and use of AKTA instrumentation (desired)
  • Experience with mammalian transient expression (desired)
  • Knowledge of and interest in learning phage display technology and its application within antibody discovery programs
What We Offer

We offer a competitive salary, a generous benefits package, and a wide range of career and personal development opportunities. Our policies and processes enable you to improve your work-life balance, take positive steps in your career, and achieve your personal wellbeing goals.

How to Apply

We operate an anonymised shortlisting process in our commitment to equality, diversity, and inclusion. CVs are required for all applications, but we won't be able to view them until we invite you for an interview. Instead, we ask you to complete the work history section of the online application form for us to be able to assess you fairly and objectively.

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