Investigator, Automated Protein Expression

1 week ago

Stevenage, United Kingdom GSK Full time

**Site Name**: UK - Hertfordshire - Stevenage

**Posted Date**: May 23 2024

We create a place where people can grow, be their best, be safe, and feel welcome, valued and included. We offer a competitive salary, an annual bonus based on company performance, healthcare and wellbeing programmes, pension plan membership, and shares and savings programme.

Discover more about our company wide benefits and life at GSK on our webpage _Life at GSK | GSK_

**Investigator, Automated Protein Expression**

Within GSK, Large Molecule Discovery (LMD) is dedicated to the discovery of novel and effective biopharmaceutical medicines. This department comprises several complementary functions focused on the progression of a portfolio of biopharmaceuticals from initial antibody discovery, expression and characterisation, to molecular engineering and biological and physiochemical profiling.

The Mid-Scale Expression team are a team of scientists within LMD with the remit of employing our modular automated protein expression system to generate antibodies at mid-scale to support GSK’s ambitious pipeline. We are seeking an experienced enthusiastic, dynamic and self-motivated lab-based scientist to join us in creating the medicines of the future.

This role would suit an inquisitive scientist skilled in mammalian cell transfection, culture and protein biochemistry. You will be involved in the use of novel automation solutions, so experience with and enthusiasm for the use of automation would be an advantage.

**In this role you will**
- Demonstrate scientific leadership and impact through a lab-based role
- Generate stable cell lines and conduct transient transfections (cell maintenance, quality control of cell culture; transfection)
- Perform protein purification using affinity and ion-exchange techniques
- Execute and troubleshoot workflows using Tecan-based automated liquid handling systems
- Design, perform and write up high quality scientific experiments in a timely manner
- Influence scientific direction and execution of projects and discovery platforms in the group

**_ Why you?_**

**Basic Qualifications & Skills**:
We are looking for professionals with these required skills to achieve our goals:

- PhD or equivalent experience in biochemical engineering, cell biology, bioprocessing or a related discipline
- Experience of stable cell line generation and transient transfection (cell maintenance, quality control of cell culture; transfection)
- Experienced in protein purification and/or characterisation
- Demonstrable ability to lead projects, identify and troubleshoot problems in the execution of experiments and support other team members
- Good attention to detail in experimental setup, reporting/writing up data and verbal presentation
- Demonstrated ability to work effectively in multi-disciplinary teams and display excellent interpersonal and communication skills

**Preferred Qualifications & Skills**:
If you have the following characteristics, it would be a plus:

- Expertise in the use and troubleshooting of automated liquid handling (in particular Tecan-based systems)
- Capable of performing complex data management and data interpretation tasks/analyses
- Troubleshooting and critique of process workflows
- Track record of building collaborations internally and/or externally

**_ Closing Date for Applications: Thursday 6th June 2024_**:
Please take a copy of the Job Description, as this will not be available post closure of the advert.

**Why GSK?**

**Uniting science, technology and talent to get ahead of disease together.**

GSK is a global biopharma company with a special purpose - to unite science, technology and talent to get ahead of disease together - so we can positively impact the health of billions of people and deliver stronger, more sustainable shareholder returns - as an organisation where people can thrive. We prevent and treat disease with vaccines, specialty and general medicines. We focus on the science of the immune system and the use of new platform and data technologies, investing in four core therapeutic areas (infectious diseases, HIV, respiratory/ immunology and oncology).

Our success absolutely depends on our people. While getting ahead of disease together is about our ambition for patients and shareholders, it’s also about making GSK a place where people can thrive. We want GSK to be a place where people feel inspired, encouraged and challenged to be the best they can be. A place where they can be themselves - feeling welcome, valued, and included. Where they can keep growing and look after their wellbeing. So, if you share our ambition, join us at this exciting moment in our journey to get Ahead Together.

As an Equal Opportunity Employer, we are open to all talent. In the US, we also adhere to Affirmative Action principles. This ensures that all qualified applicants will receive equal consideration for employment without regard to neurodiversity, race/ethnicity, colour, national origin,

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