Head of Commercial Planning

2 weeks ago

Cambridge Cambridgeshire, United Kingdom Vertex Ventures HC Full time

Bicycle Therapeutics is a clinical-stage pharmaceutical company developing a novel class of medicines, referred to as Bicycle molecules, for diseases that are underserved by existing therapeutics. This constraint facilitates target binding with high affinity and selectivity, making Bicycle molecules attractive candidates for drug development. and BT7480, a Bicycle Tumor-Targeted Immune Cell Agonist (Bicycle TICA) targeting Nectin-4 and agonizing CD137, in company-sponsored clinical trials. Additionally, the company is developing Bicycle Radio Conjugates (BRC) for radiopharmaceutical use and, through various partnerships, is exploring the use of Bicycle technology to develop therapies for diseases beyond oncology.
Bicycle Therapeutics is headquartered in Cambridge, UK, with many key functions and members of its leadership team located in Cambridge, MA USA
The Senior Director/Director, Medical Affairs Strategy will function as a scientific and medical expert for Medical Affairs, as well as other cross-functional groups across the company. This individual will be responsible for developing and executing medical affairs strategies, integrated evidence plans, and tactical plans for Bicycle asset(s). This person will provide strategic medical input into the Global Product Teams (GPTs) and represent medical affairs on GPTs as assigned by the Senior Director, Global Medical Affairs Strategy Lead. This candidate will have a successful track record of developing and driving medical strategy, including the effective communication of scientific data through publications, medical communications, scientific engagement, advisory boards, congress activities, and medical information. In addition, this individual will support data generation, life cycle management, and launch readiness activities as well as develop relationships with Key Opinion Leaders (KOLs) in support of assigned programs. This individual should have a strong background and prior experience in the field of solid tumors, with the ability to translate scientific goals into actions that align with cross-functional partners and business objectives.

S. medical affairs strategic and tactical planning, in coordination with the Global Medical Affairs Strategy Lead and other cross-functional team members
S. medical affairs launch readiness planning, activities, tracking, and execution
Lead a cross-functional Global Medical Affairs Team (GMAT) for assigned Bicycle asset(s), which includes developing, coordinating, and executing on medical strategies and tactics
Ensure strategic alignment with the field medical affairs team and support scientific communication material development to support KOL engagement
Develop and align scientific messages with cross-functional partners, including investor relations and corporate communications
Facilitate the utilization of scientific data generated by preclinical, clinical, and Real-World Evidence (RWE) studies in scientific exchange
Assist in the development, roll-out, and operation of an Investigator-Sponsored Trial (IST) program and strategy for assigned Bicycle asset(s)
Serve as a medical reviewer on the Bicycle Medical Review Committee and promotional review processes
Assure close but appropriate coordination of medical affairs strategies and activities with clinical development, clinical operations, commercial, translational, research, corporate communications, investor relations, and other key Bicycle stakeholders
Provide medical perspectives and assist in the development and strategic timing of publications (i.e., Lead the development and execution of advisory boards, including presentation of scientific content and facilitation of meetings
Engage Key Opinion Leaders (KOLs) in coordination with the field medical team and as needed
Prior biopharmaceutical industry experience is required (7+ years of experience preferred) in medical affairs and oncology drug development
Advanced degree in health-related field (MD, PhD, or PharmD strongly preferred)
Ability to think strategically and translate scientific information into medical affairs strategies
Ability to understand complex information and simplify into concise scientific messages
Strategic thinking with strong business acumen and the ability to prioritize
Proficiency in clinical trial data review and interpretation
S. healthcare systems and understanding of region regulatory requirements
Occasional business travel required (~25%)
Flexible working environment
~ Competitive reward including annual company bonus
~ Medical, dental, and vision insurance for eligible employees and their families with 100% of the premiums covered by the Company
~ Health and Dependent Care Flexible Spending Accounts
~401(k) plan with a 4% Company match and immediate vesting
~ Eligibility to accrue up to 23 paid time off days per full year worked, plus the option to buy up to 5 additional days
~ Employee assistance program
~ Employee recognition schemes
~10 Company holidays
~ Competitive Family Leave Policy
~ Eligibility for an option grant to subscribe to shares in Bicycle Therapeutics plc.

Bicycle Therapeutics is committed to building a diverse workforce that is representative of the communities we serve. Therefore, all qualified applicants will be considered for employment, and we do not discriminate on the basis of race, religion, colour, gender, sexual orientation, age, disability status, marital status, or veteran status.

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