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Senior/Principal Scientist MSAT Cell Therapy

2 months ago

London, United Kingdom Northreach Full time

Job Title: Senior Scientist MSAT - Cell Therapy

Job Type: Full-Time


Northreach is a dynamic recruitment agency that connects businesses with top talent in the Advanced Therapies sector. Our mission is to provide a seamless and personalised recruitment experience for clients and candidates, and to create a positive work environment that encourages equality, innovation, and professional growth.


About Us:

My client are a pioneering biotechnology company at the forefront of cell-based therapies. We are seeking a highly skilled and experienced Senior Scientist to join our dynamic MSAT team. This role offers a unique opportunity to contribute to the advancement of cutting-edge T cell therapies for the treatment of serious medical conditions


Responsibilities:

  • Provide project management and technical expertise to production teams as owners of the manufacturing process.
  • Support development, tech-transfer, and validation activities, ensuring close partnership through open and transparent communication, scientific and strategic understanding, and attention to priorities and details.
  • Establish effective relationships and partner with cross-functional stakeholders (PM, QC, QA, Supply Chain, production, AD, PD and Regulatory) as needed to enable tech transfers and PPQ campaigns.
  • Lead the development of processes and systems for the management of data, trending, and analysis.
  • Assess opportunities for continuous improvement of the manufacturing processes based on trend analysis, advances in manufacturing technology and controls and new industry standards.
  • Participate and present as an integral project member of internal or external projects as a drug product MSAT technical expert.
  • Confirm equipment qualification as a part of the process validation process (e.g. correct installation, efficient operation, robust performance).
  • You will establish training programmes, coach, mentor, and train technical and production operators to ensure a high-performing technical operations and MSAT teams.
  • Take an active role in the evaluation of deviations, root-cause-analysis, corrective action preventive action (CAPA) and change control processes with strong focus on quality, risk mitigation and regulatory compliance.


Qualifications:

  • Detailed understanding of immunology and cell therapy.
  • Demonstrable expertise in cell-based techniques including cell enrichment, culture, and formulation technologies.
  • Ability to lead and manage a team, work independently and collaboratively with cross-functional teams across multiple sites.
  • Resourcefulness in overcoming challenges and possess the ability to thrive in a fast-paced environment.
  • Experienced in working closely with production teams, leading root cause analysis and assessing non-product quality impacting deviations.
  • Authors and reviews batch records, bill of materials and change controls. Assesses change controls for impact of any change to the process, equipment, or procedures.
  • Good understanding of working with quality management systems (e.g. Q-Pulse)
  • Knowledge of tech transfer and working with CDMOs desirable.
  • Training in Six Sigma and/or manufacturing excellence methodologies is advantageous.


Technical Requirements:

  • Excellent time and project management skills.
  • Minimum MSc in relevant study field and 4 years’ experience in industry and/or academia
  • Proven commitment to high quality work and maintenance of high standards.
  • Contribute to a culture that embraces scientific excellence, integrity, urgency, patient centricity, and continuous improvement.
  • Experience working in cGMP development and/or cell therapy product manufacturing is highly desirable.


Personal Qualities

  • Ability to work collaboratively within a team, supporting one another and held accountable for project deliverables.
  • Personal drive and goal orientation.
  • Detail-orientated and accurate.
  • Professional and personable communication skills.
  • Driven to solve problems pragmatically.
  • Demonstrates strong organisational and prioritisation skills to manage a diverse workload.
  • Excellent working attitude, reliability, and flexibility.
  • Flexibility to work across multiple sites in London


Benefits:

We offer a competitive salary package commensurate with experience, along with comprehensive benefits including medical, dental, and vision coverage, retirement plans, and opportunities for professional growth within a rapidly evolving field.


If you are a dedicated and innovative scientist with a passion for advancing T cell-based therapies, we encourage you to apply and be part of our mission to revolutionize patient care through ground breaking cell therapies.


Northreach is an equal opportunity employer and we do not discriminate against any employee or applicant for employment based on race, colour, religion, sex, national origin, disability, or age. We are committed to promoting diversity, equity, and inclusion in the workplace and hiring practices, therefore only partner with business that promote DEI. We strive to create a welcoming and inclusive environment for all employees.