Pre-announcement: Novel human in vitro models of complex disease

2 months ago


Swindon, United Kingdom NERC - the Natural Environment Research Council Full time
Opportunity status: Upcoming Funders: , , Co-funders: National Centre for the Replacement, Refinement and Reduction of Animals in Research (NC3Rs) Funding type: Grant Total fund: £10,000,000 Publication date: 20 September 2024 Opening date: 5 November 2024 9:00am UK time Closing date: 20 March 2025 4:00pm UK time

Apply for funding to lead a cluster in a coordinated network for novel human in vitro models of complex disease.

You must:

  • be based at an organisation eligible for MRC funding
  • meet individual eligibility requirements

Clusters should be focused on:

  • the development, validation and adaptation of human in vitro disease models for ready adoption by end users in academia, industry or both
  • specific disease areas of high unmet need or addressing common needs with relevance to multiple disease domains

We anticipate funding three clusters from the total fund of £10 million.

The duration of each awarded cluster is expected to be four years.

This is a pre-announcement and the information may change. The full application stage will open on 5 November 2024. More information will be available on this page then.

Who can apply

Before applying for funding, check the .

UK Research and Innovation (UKRI) has introduced new role types for funding opportunities being run on the new UKRI Funding Service.

For full details, visit .

Who is eligible to apply

To be eligible to apply for this funding opportunity you must:

  • be employed by an
  • meet individual eligibility requirements
  • show that you will direct the project and be actively engaged in the work
  • have the relevant expertise and experience to lead a multi-organisation project

For applicants who do not have a contract of employment for the duration of the proposed project, by submitting an application the research organisation is confirming, if it is successful:

  • contracts will be extended beyond the end date of the project
  • all necessary support for the project and the applicants will be provided, including mentorship and career development for early career researchers

You may only submit one application as a project lead, however you may be involved as part of the research team on other applications.

Host research organisations

Applications can be from a single eligible organisation or a partnership of organisations.

When there are two or more eligible organisations involved, for administrative purposes it is necessary to identify a single project lead who must be affiliated with the lead research organisation. However, the balance of activity and leadership across the participants and partner organisations can be equally shared if desirable. What is critical is for the approach to leadership and decision making across multiple organisations to be clearly specified where applicable.

Who is not eligible to apply

You are not eligible to apply for this funding opportunity as a project lead if you are based at an international research organisation. This does not include Medical Research Council (MRC) Unit The Gambia or MRC/UVRI Uganda Research Unit at the London School of Hygiene and Tropical Medicine that are eligible to apply as project lead. Before applying for funding, check the .

International applicants

You can include international applicants as project co-leads (international), where they will make a major intellectual contribution to the design or conduct of the project.

Equality, diversity and inclusion

We are committed to achieving equality of opportunity for all funding applicants. We encourage applications from a diverse range of researchers.

We support people to work in a way that suits their personal circumstances. This includes:

  • career breaks
  • support for people with caring responsibilities
  • flexible working
  • alternative working patterns



  • Swindon, Swindon, United Kingdom NERC - the Natural Environment Research Council Full time

    Lead a Cluster in Novel Human In Vitro Models of Complex DiseaseWe are seeking an exceptional researcher to lead a cluster in a coordinated network for novel human in vitro models of complex disease. This is a unique opportunity to develop, validate, and adapt human in vitro disease models for ready adoption by end users in academia, industry, or both.About...


  • Swindon, Swindon, United Kingdom NERC - the Natural Environment Research Council Full time

    Job OpportunityWe are seeking a highly skilled researcher to lead the development of novel human in vitro models for complex diseases.This is an exciting opportunity to contribute to the advancement of disease research and to work with a talented team of scientists.Key Responsibilities:Develop and validate human in vitro disease modelsCollaborate with...


  • Swindon, Swindon, United Kingdom NERC - the Natural Environment Research Council Full time

    Opportunity OverviewWe are seeking a highly skilled and experienced researcher to lead a cluster in a coordinated network for novel human in vitro models of complex disease.Key ResponsibilitiesDevelop, validate, and adapt human in vitro disease models for ready adoption by end users in academia, industry, or both.Focus on specific disease areas of high unmet...


  • Swindon, Swindon, United Kingdom NERC - the Natural Environment Research Council Full time

    We are seeking a Collaborative Researcher to join our team at NERC, the Natural Environment Research Council. This exciting opportunity is part of an international collaboration to understand the ecological, evolutionary and social drivers of infectious disease transmission in animals, humans and plants.Job OverviewThis role will involve working with a...


  • Swindon, Swindon, United Kingdom NERC - the Natural Environment Research Council Full time

    Research OpportunityWe are seeking a collaborative research team to investigate the ecological, evolutionary, and social drivers of infectious disease transmission in animals, humans, and plants.The project will involve a quantitative or mathematical approach combined with qualitative principles to understand the complex dynamics of infectious disease...


  • Swindon, Swindon, United Kingdom NERC - the Natural Environment Research Council Full time

    Opportunity OverviewNERC is seeking a researcher to collaborate with the functional genomics screening laboratory (FGSL) on CRISPR screening projects. The successful candidate will work with scientists employed by the Milner Therapeutics Institute to better understand model biology and enable target identification.Key ResponsibilitiesCollaborate with the...


  • Swindon, Swindon, United Kingdom NERC - the Natural Environment Research Council Full time

    The Natural Environment Research Council (NERC) invites researchers to collaborate with the functional genomics screening laboratory on projects using complex human in vitro models for CRISPR screening.As a researcher, you will have the opportunity to work with the FGSL on projects that aim to better understand model biology and enable target...


  • Swindon, United Kingdom NERC - the Natural Environment Research Council Full time

    Opportunity status: Open Funders: Co-funders: AstraZeneca, University of Cambridge Funding type: Other Publication date: 18 April 2024 Opening date: N/A Closing date: Open - no closing date ...


  • Swindon, United Kingdom NERC - the Natural Environment Research Council Full time

    Opportunity status: Open Funders: , , , , Co-funders: Department for Environment, Food and Rural Affairs (Defra), United States (US) National Science Foundation (NSF), US National Institutes of Health (NIH), US National Institute of Food and Agriculture Department of Agriculture (USDA-NIFA), US–Israel...


  • Swindon, United Kingdom MCG Healthcare Full time

    OverviewMCG Healthcare is a dynamic and innovative CQC-rated GOOD 2-site GP Practice in Swindon. We are committed to providing excellent patient care, and our forward-thinking approach sets us apart from other practices.We offer an attractive salary package that is commensurate with experience, ensuring that our nurses are rewarded for their skills and...

  • Motor Neurone Disease

    6 months ago


    Swindon, United Kingdom Prospect Hospice Full time

    The MND health care assistant is responsible for assisting the specialist MND practitioner to coordinate the assessment, treatment and support for people living with MND and their families within Swindon. To work with individuals across the community, within acute settings, Hospitals, Hospice and nursing homes, The prime purpose is to support the MND...

  • AI Model Trainer

    1 month ago


    Swindon, Swindon, United Kingdom Outlier Full time

    About the Opportunity:Outlier is seeking a skilled English language expert to contribute to the development of generative artificial intelligence models. As a Human Feedback Specialist, you will play a crucial role in improving the accuracy and effectiveness of these models.Key Responsibilities:Read and evaluate English text to assess the quality of...


  • Swindon, Swindon, United Kingdom NHS Full time

    About the OpportunityWe are seeking a highly motivated and proactive Band 6 Specialist Nurse to join our Hepatology team at Great Western Hospitals NHS Foundation Trust. This is a 12-month opportunity to contribute to the development of our service and play a key role in the care of patients with acute and chronic liver disease.Job SummaryThe successful...

  • Risk Modeller

    4 weeks ago


    Swindon, Swindon, United Kingdom Nationwide Building Society Full time

    About this roleThis is an exciting opportunity to join our Risk Decision & Data Science team, winners of the "Credit Modelling & Risk Team of the Year" at both the 2022 and 2020 Credit Strategy Awards, "Best Use of Technology" at the 2019 Credit Strategy Awards, and winners at the Women in Credit Awards for "Rising Star of the Year" (2022 and 2023) and "Team...


  • Swindon, Swindon, United Kingdom Outlier Full time

    Outlier's Mission:To empower AI models by providing high-quality human feedback.We partner with innovative companies to improve their AI models, and we're seeking experienced software engineers to lend their expertise in training these models.The Role:Crafting and answering complex computer science questions to train AI models.Evaluating and ranking code...

  • Data Designer

    5 months ago


    Swindon, United Kingdom Openwork Full time

    **The opportunity**: As an integral part of the multi-function Data Engineering Team provide data architecture, data design, and data modelling direction for Openwork’s data lake, dimensional model, reporting, and information systems. **The benefits**: - Salary - £50,000 to £65,000 - Bonus scheme - on target bonus 10% - Pension scheme - contribute up...


  • Swindon, United Kingdom Great Western Hospitals NHS Foundation Trust Full time

    Job summary ***previous candidates need not apply*** An opportunity has arisen with the Hepatology specialist nursing team to recruit a Band 6 Hepatology Specialist Nurse for 12 months. We are looking for a highly motivated, proactive and enthusiastic nurse to help with the continued development of this service. Previous experience within the...


  • Swindon, Swindon, United Kingdom NERC - the Natural Environment Research Council Full time

    Develop your expertise in therapeutic innovation by leading the development and testing of novel medical solutions.About NERCNERC, the Natural Environment Research Council, is a world-leading research organisation dedicated to advancing our understanding of the natural environment. As a member of our team, you will have the opportunity to contribute to...


  • Swindon, Swindon, United Kingdom NERC - the Natural Environment Research Council Full time

    Opportunity OverviewThis funding opportunity is aimed at investigating the causes, progression, and treatment of human disease. The project must focus on a mechanistic hypothesis and include an experimental intervention or challenge in humans.Eligibility CriteriaApplicants must be employed by an eligible research organisation.Applicants must demonstrate that...

  • Risk Analyst

    1 month ago


    Swindon, Swindon, United Kingdom Nationwide Full time

    We are seeking a highly skilled Risk Analyst to join our Retail Financial Modelling team at Nationwide. As a Risk Analyst, you will play a key role in supporting the development and maintenance of our provisions (IFRS9) and forecasting models on all Unsecured portfolios (Credit Cards, Personal Loans and Current Accounts).The successful candidate will have a...