Research Fellow

4 weeks ago


London, United Kingdom UCL Eastman Dental Institute Full time

About the role

We are seeking a talented and highly motivated computational biologist (Postdoctoral Research Fellow) to join our established and dedicated team of researchers using human induced pluripotent stem cells to study Motor Neuron Disease (ALS).

Based in the laboratory of Professor Rickie Patani, you will be joining a team of experimental scientists working on resolving the molecular basis of motor neuron degeneration with a particular focus on the relationship between DNA damage and aberrant RNA metabolism using established human stem cell models of ALS. As main bioinformatician working on the project, you will analyse diverse datasets deriving from cutting-edge sequencing approaches (such as DRIP-seq, INDUCE-seq and bulk RNAseq, etc.), to explore the complex functional interaction between these processes. This exciting project is developed as part of an established collaboration with Prof. Simon Boulton’s lab at the Francis Crick Institute.

This is a compelling opportunity to contribute to ground-breaking, high-impact research projects within an intellectually stimulating, globally diverse scientific community.

The role is available immediately and funded by My Name’5 Doddie Foundation for two years in the first instance.

If you need reasonable adjustments or a more accessible format to apply for this job online, or have any queries regarding the application process, please contact the Institute of Neurology HR Team ().

Informal enquiries regarding the role can be addressed to Professor Rickie Patani ().

A full job description and person specification for this role can be accessed below.

About you

You will have a PhD in a relevant subject (computational biology, bioinformatics, statistics, neuroscience, etc.), and significant computational experience in mathematical modelling of complex biological data and in using R/Python and/or other programming languages. Proven experience analysing bulk RNAseq datasets, with specific focus on splicing and RNA processing is also required for this job.

This role meets the eligibility requirements for a skilled worker certificate of sponsorship or a global talent visa under UK Visas and Immigration legislation. Therefore, UCL welcomes applications from international applicants who require a visa.

What we offer

Starting salary offered in the rage £42, - £49, per annum.

Appointment as Research Fellow is dependent upon having been awarded a PhD; if this is not the case, initial appointment will be as Research Assistant (salary £37, - £39, per annum) with appointment as Research Fellow being backdated to the date of final submission of the PhD thesis.

As well as the exciting opportunities this role presents, we also offer great benefits, some of which are below:

41 Days holiday (27 days annual leave 8 bank holiday and 6 closure days) Additional 5 days’ annual leave purchase scheme Defined benefit career average revalued earnings pension scheme (CARE) Cycle to work scheme and season ticket loan Immigration loan Relocation scheme for certain posts On-site nursery On-site gym Enhanced maternity, paternity and adoption pay Employee assistance programme: Staff Support Service Discounted medical insurance

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