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Bioanalytical Associate Technical Specialist

2 months ago

Saffron Walden, United Kingdom Charles River Laboratories, Inc. Full time

For 75 years, Charles River employees have worked together to assist in the discovery, development and safe manufacture of new drug therapies. When you join our family, you will have a significant impact on the health and well-being of people across the globe. Whether your background is in life sciences, finance, IT, sales or another area, your skills will play an important role in the work we perform. In return, we’ll help you build a career that you can feel passionate about.

Job Summary


Our Charles River Discovery, Saffron Walden site have an opportunity for an Associate Technical Specialist (Bioanalysis),

 

This is a lab-based role in our Drug Metabolism and Pharmacokinetic (DMPK) team with a focus on accurately measuring concentrations of potential new therapies in biological samples.

 

At Charles River, you will be an integral part of our DMPK team working in a motivated and supportive environment. You will rapidly develop lab skills, as well as working closely with colleagues in multidisciplinary teams to deliver results to your clients.

 

In addition to developing your practical skills, you will have opportunities to expand your non-lab skills within areas such as communication, scientific writing and operational or continuous improvement initiatives, whilst learning about the drug discovery process in a fast-moving and dynamic Contract Research Organisation.


 

What You'll Be Doing

 

  • You will be processing biological samples to determine the concentration of novel compounds designed to treat a range of medical conditions. This data is used to select the compounds with the best chance of meeting all the criteria to become a new drug. Attention to detail, accuracy and precision are key

 

  • You will be using mass spectrometers to detect each compound.

 

  • Full training will be given in every step of the process, from developing and optimising the detection methods, to sample and data processingAs your confidence in using and understanding the instruments grows you will also perform routine instrument validation and maintenance dutiesYou will maintain a safe working environment, and be expected to be an active participant on the general laboratory housekeeping rota’s.

 

  • The data you generate will be used to determine the pharmacokinetic (PK) profile of compounds and understand the relationship between concentration and effect (pharmacokinetic and pharmacodynamic (PK/PD) relationships), and in support of predicting the dose required in humans to have the desired outcome whilst maintaining safety margin.

 

Skills and Experience

 

  • BSc in a scientific discipline.

 

  • Prior internship / work experience / shadowing.

 

  • Previous work experience at similar CROs / pharma / biotech companies is advantageous.

 

  • Effective communicator.

 

  • Works effectively as part of a team.

 

  • Attention to detail.

 

  • Strong desire to develop a lab-based career discovering new medicines.

 

What We Offer You

 

  • A very comprehensive benefits package from day one, including a generous pension contribution, private medical for you (and can add family members), private dental care, critical illness cover, bonus and more

 

  • Access to great discounts via our CREDS discount scheme.

 

  • Global opportunities and strong career progression.

 

  • The chance to work on several varied projects and liaise globally and nationally with other business areas.

 

  • To be able make a difference to health and wellbeing of people.

 

  • To continue your own career growth.

 

  • Flexible and hybrid working.

 

  • Parental leave.

 

  • Group Life Assurance and Group Income Protection.

 

  • Remote GP access 24/7.

 

  • Well-being support and initiatives.

 

  • Cycle to work scheme.

 

  • Well-being support and initiatives.

 

  • Cycle to work scheme.

 

About Discovery
Discovery from Charles River is industry-proven in the successful development of novel therapies, with over 350 patents and 80 preclinical drug candidates delivered to our sponsors in the past 17 years. Backed by more than 650 scientists, our comprehensive, integrated portfolio employs the latest technology and platforms to provide chemistry, biology, and pharmacology services that support clients from the earliest stages of hit identification all the way through to IND. Our client-focused, collaborative approach creates true partnerships that anticipate challenges, overcome obstacles, and move us forward together on the journey of getting new drugs to market.

 

About Charles River
Charles River is an early-stage contract research organization (CRO). We have built upon our foundation of laboratory animal medicine and science to develop a diverse portfolio of discovery and safety assessment services, both Good Laboratory Practice (GLP) and non-GLP, to support clients from target identification through preclinical development. Charles River also provides a suite of products and services to support our clients’ clinical laboratory testing needs and manufacturing activities. Utilizing this broad portfolio of products and services enables our clients to create a more flexible drug development model, which reduces their costs, enhances their productivity and effectiveness to increase speed to market.

 

With over 20,000 employees within 110 facilities in over 20 countries around the globe, we are strategically positioned to coordinate worldwide resources and apply multidisciplinary perspectives in resolving our client’s unique challenges. Our client base includes global pharmaceutical companies, biotechnology companies, government agencies and hospitals and academic institutions around the world. 

 

At Charles River, we are passionate about our role in improving the quality of people’s lives. Our mission, our excellent science and our strong sense of purpose guide us in all that we do, and we approach each day with the knowledge that our work helps to improve the health and well-being of many across the globe. We have proudly supported the development of 86% of the drugs approved by the FDA in 2021.

 

At Charles River Laboratories, we recognize and recruit all talent. We are a company committed to the principle of diversity and inclusion and work daily in this direction.