Head of Research And Development

2 months ago


UK, UK, United Kingdom DNA Life Sciences Full time

My client is a clinical stage biopharma company developing novel CNS therapeutic products.


Roles and Responsibilities

  • Develop and lead Discovery and Preclinical Research strategies for lead and pipeline programs.
  • Manage daily activities, team, and budget, ensuring contingency plans are in place.
  • Produce pharmacology data to standards and create development hypotheses in CNS therapeutic areas.
  • Coordinate with third parties (CROs, partners, academic centres) to achieve strategic goals.
  • Oversee preclinical regulatory submissions and interactions with agencies (FDA, MHRA, EMA, TGA, etc.).
  • Collaborate with Clinical Development and Chief Medical Officer on trial designs and protocols.
  • Partner with Intellectual Property team to identify and secure IP from research activities.
  • Ensure studies adhere to SOPs and regulatory guidelines.
  • Design nonclinical programs in compliance with ICH requirements for smooth phase transitions.
  • Maintain Preclinical GxP and Health & Safety standards through ongoing training.


Experience, Skills, and Qualifications

  • Degree in Pharmacology or related field; PhD preferred.
  • Extensive senior-level experience in Pharmacology and Preclinical research within the pharmaceutical industry.
  • Knowledge of preclinical drug development legislation and guidelines.
  • Experience in scientific technical writing for regulatory documents and publications.
  • Proven presentation skills at national and international forums.
  • Strong budget management and organizational skills.
  • Effective problem-solving and time management abilities.
  • Leadership experience in team management and development.
  • Excellent written and verbal communication skills.
  • Proficiency in Excel, Word, PowerPoint, EndNote, literature search engines, and scientific software (e.g., GraphPad).


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