Current jobs related to Principal Scientist - Oxford UK, Oxfordshire - Yellowstone Biosciences
-
Principal Research Scientist
1 month ago
Oxford, Oxfordshire, United Kingdom Vertex Full timeJob Title: Principal Research Scientist, Computational Genomics LeadWe are seeking a highly skilled Principal Research Scientist to lead our Computational Genomics team at our Oxford UK Research site. As a key member of our global Computational Genomics team, you will design and execute genomic studies to advance our drug discovery programs.Key...
-
Principal Research Scientist
1 month ago
Oxford, Oxfordshire, United Kingdom Vertex Full timeJob Title: Principal Research Scientist, Computational Genomics LeadWe are seeking a highly skilled Principal Research Scientist to lead our Computational Genomics team at our Oxford UK Research site. As a key member of our global Computational Genomics team, you will design and execute genomic studies to advance our drug discovery programs.Key...
-
Principal Research Scientist
4 weeks ago
Oxford, Oxfordshire, United Kingdom Vertex Full timeJob Title: Principal Research Scientist, Computational Genomics LeadWe are seeking a highly skilled Principal Research Scientist to lead our Computational Genomics team at our Oxford UK Research site. As a key member of our global Computational Genomics team, you will design and execute genomic studies to advance our drug discovery programs.Key...
-
Principal Research Scientist
4 weeks ago
Oxford, Oxfordshire, United Kingdom Vertex Full timeJob Title: Principal Research Scientist, Computational Genomics LeadWe are seeking a highly skilled Principal Research Scientist to lead our Computational Genomics team at our Oxford UK Research site. As a key member of our global Computational Genomics team, you will design and execute genomic studies to advance our drug discovery programs.Key...
-
Principal Research Scientist
1 month ago
Oxford, Oxfordshire, United Kingdom Vertex Full timeJob Title: Principal Research Scientist, Computational Genomics LeadWe are seeking a highly skilled Principal Research Scientist to lead our Computational Genomics team at our Oxford UK Research site. As a key member of our global Computational Genomics team, you will design and execute genomic studies to advance our drug discovery programs.Key...
-
Principal Research Scientist
1 month ago
Oxford, Oxfordshire, United Kingdom Vertex Full timeJob Title: Principal Research Scientist, Computational Genomics LeadWe are seeking a highly skilled Principal Research Scientist to lead our Computational Genomics team at our Oxford UK Research site. As a key member of our global Computational Genomics team, you will design and execute genomic studies to advance our drug discovery programs.Key...
-
PhD Research Scientist
4 weeks ago
Oxford, Oxfordshire, United Kingdom Immunocore Full timePrincipal Scientist, Antibody PlatformVacancy No: VN469Employment Type: Full TimeLocation of role: Oxford, UKJob SummaryWe are seeking a highly skilled Principal Scientist to join our Antibody Platform team. As a key member of our Protein Engineering team, you will provide scientific and technical expertise in antibody discovery and engineering to drive our...
-
PhD Research Scientist
4 weeks ago
Oxford, Oxfordshire, United Kingdom Immunocore Full timePrincipal Scientist, Antibody PlatformVacancy No: VN469Employment Type: Full TimeLocation of role: Oxford, UKJob SummaryWe are seeking a highly skilled Principal Scientist to join our Antibody Platform team. As a key member of our Protein Engineering team, you will provide scientific and technical expertise in antibody discovery and engineering to drive our...
-
PhD Research Scientist
1 month ago
Oxford, Oxfordshire, United Kingdom Immunocore Full timePrincipal Scientist, Antibody PlatformVacancy No: VN469Employment Type: Full TimeLocation of role: Oxford, UKJob SummaryWe are seeking a highly skilled Principal Scientist to join our Antibody Platform team. As a key member of our Protein Engineering team, you will provide scientific and technical expertise in antibody discovery and engineering to drive our...
-
PhD Research Scientist
1 month ago
Oxford, Oxfordshire, United Kingdom Immunocore Full timePrincipal Scientist, Antibody PlatformVacancy No: VN469Employment Type: Full TimeLocation of role: Oxford, UKJob SummaryWe are seeking a highly skilled Principal Scientist to join our Antibody Platform team. As a key member of our Protein Engineering team, you will provide scientific and technical expertise in antibody discovery and engineering to drive our...
-
Principal Radiotherapy Physicist
4 weeks ago
Oxford, Oxfordshire, United Kingdom NHS Full timeOxford University Hospitals NHS Foundation TrustWe are seeking a highly skilled and experienced Radiotherapy Physicist to join our dynamic team at the Oxford University Hospitals NHS Foundation Trust. As a Principal Radiotherapy Physicist, you will play a key role in the development and implementation of radiotherapy services, working closely with our team...
-
Principal Radiotherapy Physicist
4 weeks ago
Oxford, Oxfordshire, United Kingdom NHS Full timeOxford University Hospitals NHS Foundation TrustWe are seeking a highly skilled and experienced Radiotherapy Physicist to join our dynamic team at the Oxford University Hospitals NHS Foundation Trust. As a Principal Radiotherapy Physicist, you will play a key role in the development and implementation of radiotherapy services, working closely with our team...
-
Oxford, Oxfordshire, United Kingdom Vertex Pharmaceuticals Full timeUnlocking the Power of GenomicsWe are seeking a highly skilled computational biology leader to join our team at Vertex Pharmaceuticals. As the Computational Genomics Lead for our Oxford Research Site, you will play a critical role in advancing our understanding of genomics and its application in drug development.Key ResponsibilitiesCollaborate with our...
-
Oxford, Oxfordshire, United Kingdom Vertex Pharmaceuticals Full timeUnlocking the Power of GenomicsWe are seeking a highly skilled computational biology leader to join our team at Vertex Pharmaceuticals. As the Computational Genomics Lead for our Oxford Research Site, you will play a critical role in advancing our understanding of genomics and its application in drug development.Key ResponsibilitiesCollaborate with our...
-
Principal Scientist
1 month ago
Oxford, Oxfordshire, United Kingdom HR Wallingford Full timeAbout the RoleWe are seeking a highly motivated and experienced Water Quality Specialist to join our Catchment and Drainage Team at HR Wallingford. As a key member of our team, you will play a crucial role in delivering innovative research and consultancy solutions for our clients.As a Water Quality Specialist, you will be responsible for providing...
-
Principal Scientist
1 month ago
Oxford, Oxfordshire, United Kingdom HR Wallingford Full timeAbout the RoleWe are seeking a highly motivated and experienced Water Quality Specialist to join our Catchment and Drainage Team at HR Wallingford. As a key member of our team, you will play a crucial role in delivering innovative research and consultancy solutions for our clients.As a Water Quality Specialist, you will be responsible for providing...
-
Computational Genomics Expert
1 week ago
Oxford, Oxfordshire, United Kingdom Vertex Full timeJob Title: Principal Research Scientist, Computational Genomics Lead for Oxford Research SiteVertex is seeking a highly skilled and experienced Principal Research Scientist to lead our Computational Genomics team in Oxford. As a key member of our global research team, you will be responsible for designing and executing genomic studies to advance our drug...
-
Drainage Team Principal
3 weeks ago
Oxford, Oxfordshire, United Kingdom Ecocareers Full timeExciting Opportunity in Drainage ScienceWe are seeking a highly motivated and experienced drainage scientist to lead and deliver our work in the drainage and sustainable surface water management sectors. The successful candidate will have a strong technical background and excellent proposal and project management and delivery skills.About the RoleThis is an...
-
Drainage Team Principal
3 weeks ago
Oxford, Oxfordshire, United Kingdom Ecocareers Full timeAbout the RoleWe are seeking an experienced drainage scientist to lead and deliver our work in the drainage and sustainable surface water management sectors. The successful candidate will have a strong technical background and excellent proposal and project management and delivery skills.Key ResponsibilitiesLead and deliver research and consultancy projects...
-
Drainage Team Principal
3 weeks ago
Oxford, Oxfordshire, United Kingdom Ecocareers Full timeAbout the RoleWe are seeking an experienced drainage scientist to lead and deliver our work in the drainage and sustainable surface water management sectors. The successful candidate will have a strong technical background and excellent proposal and project management and delivery skills.Key ResponsibilitiesLead and deliver research and consultancy projects...
Principal Scientist
2 months ago
We are looking for a Principal Scientist to join our cell biology team. If you're a motivated individual who excels in teamwork, is eager to grow, and excited about being part of a start-up, we'd love to connect with you.
Role Summary
In this role you will be a core part of the Cell Biology team, designing and troubleshooting assays to examine the binding of TCR bispecific molecules to cells, the activation of T cells and T-cell mediated killing. The applicant will lead programmes, input into strategy and design of the pipeline and mentor junior staff. Ideally, the applicant will have a strong knowledge of immunology and should be confident in a range of cell biology and immunology assays including techniques such as cell culture, flow cytometry, T cell activation and killing assays, cytokine assays, mammalian cell transfection/transduction and microscopy.
Key Deliverables
- Working proactively with the team to develop effective in vitro testing strategies prioritised to the needs of the biology group; collaborating effectively with other research functions, for example, Protein Engineering and CMC teams to guide optimisation and development of soluble TCRs.
- Effectively design and conduct experimental work to align with Company priorities and meet scientific timelines, report results succinctly and effectively.
- Design, conduct, analyse experiments to test safety and efficacy of soluble TCR bispecific molecules generated by the Protein Engineering team.
- Dissect molecular mechanisms of T cell activation and T cell mediated killing by soluble TCR bispecific molecules, including deploying suitable assays and sourcing required cell lines, human organoids and primary human cells and tissue samples or developing suitable model cell lines expressing genes of interest.
- Drive innovation and continuous improvement within the Cell Biology team, implementing novel technologies, workflows, and methodologies to enhance productivity and accelerate the drug development process.
- Support an in vivo testing strategy via an outsourced model as required.
- Present scientific findings and summary conclusions to your department, project team and the company leadership team.
Experience/Qualifications Required
- Familiarity with a range of cell and molecular biology techniques, such as flow cytometry analysis, T cell assays, killing assays, cytokine assays, designing and executing recombinant DNA sub-cloning strategies, making lentiviral supernatants, lentiviral transduction.
- Direct hands-on laboratory experience in testing and developing of biologics including the assessment of the biological impact of their engagement with therapeutic targets.
- Experience leading projects, overseeing the experimental strategy and co-ordinating the work of other team members.
- A PhD in a relevant biological subject with or without post-doctoral experience in academia and/or with substantial subsequent biotechnology or pharmaceutical industry experience in R&D teams.
- Ability to independently lead programmes to advance the company’s goals, review competing priorities and recommend strategies to advance the programme.
- Working proactively with the team to develop effective strategies prioritised to the needs of the Biology group; collaborating effectively with other functions.
- Inclusive, collaborative, and thrives in a team environment with a flexible approach to working.
- Strong communication skills with the confidence and judgement to challenge appropriately.
- Demonstrable problem-solving ability, creative thinking and be pro-active in driving the project forwards.
- (Desired but not essential) Experience in the design and oversight of in vivo experiments.
