Principal Research Scientist

1 day ago

Oxford, Oxfordshire, United Kingdom Vertex Full time
Job Title: Principal Research Scientist, Computational Genomics Lead

We are seeking a highly skilled Principal Research Scientist to lead our Computational Genomics team at our Oxford UK Research site. As a key member of our global Computational Genomics team, you will design and execute genomic studies to advance our drug discovery programs.

Key Responsibilities:
  • Collaborate with disease project teams to identify key project questions or challenges that can be answered using genomics, sequencing, or bioinformatics contributions.
  • Partner with Computational Genomics leads at our Boston and San Diego sites to prioritize global computational genomic needs.
  • Execute prioritized computational genomic activities in the Oxford UK research site and provide regular progress updates to Oxford leadership.
  • Perform advanced computational analyses of large-scale sequencing data and other biological data.
  • Distil complex analyses and scientific results into key take-home messages and recommendations for next steps.
  • Develop guidelines for best practices for key genomic analyses and partner with genomics method development team and global computational genomics leadership to prioritize, develop, and evolve computational methods.
Requirements:
  • Relevant education in computational biology, bioinformatics, human genetics, genomics, systems biology, bioengineering, or a related field, and relevant industry or post-doctoral experience.
  • A proven track record in the analysis, visualization, and interpretation of large-scale human genetic data in a drug development context.
  • Demonstrated ability to work across cross-functional teams to design and implement experiments, and execute computational analysis.
  • Expertise in applying computational methods and bioinformatics tools to large-scale data; proficiency with R or Python, Linux/Unix systems, and high-performance computing systems.
  • Solid understanding of statistics and genetics, including the role of genetic variation in human disease.
  • Excellent presentation and communication skills, including the ability to tailor scientific content to audiences with different backgrounds.

  • Principal Research Scientist

    5 days ago

    Oxford, Oxfordshire, United Kingdom Vertex Full time

    Job Title: Principal Research Scientist, Computational Genomics LeadWe are seeking a highly skilled Principal Research Scientist to lead our Computational Genomics team at our Oxford UK Research site. As a key member of our global Computational Genomics team, you will design and execute genomic studies to advance Vertex's drug discovery programs.Key...

  • Principal Research Scientist

    5 days ago

    Oxford, Oxfordshire, United Kingdom Vertex Full time

    Job Title: Principal Research Scientist, Computational Genomics LeadWe are seeking a highly skilled Principal Research Scientist to lead our Computational Genomics team at our Oxford UK Research site. As a key member of our global Computational Genomics team, you will design and execute genomic studies to advance Vertex's drug discovery programs.Key...

  • Principal Researcher

    3 weeks ago

    Oxford, Oxfordshire, United Kingdom S3 Science Full time

    Job Summary:S3 Science is seeking a highly skilled Principal Scientist to join our team in Oxford. As a key member of our research team, you will lead innovative research in cell and gene therapy, leveraging your expertise in gene editing, cell engineering, and cell culture.Key Responsibilities:Develop and execute technical and strategic plans for process...

  • Principal Researcher

    3 weeks ago

    Oxford, Oxfordshire, United Kingdom S3 Science Full time

    Job Summary:S3 Science is seeking a highly skilled Principal Scientist to join our team in Oxford. As a key member of our research team, you will lead innovative research in cell and gene therapy, leveraging your expertise in gene editing, cell engineering, and cell culture.Key Responsibilities:Develop and execute technical and strategic plans for process...

  • Principal Clinical Scientist

    7 days ago

    Oxford, Oxfordshire, United Kingdom Oxford University Hospitals Full time

    Job OverviewWe are seeking a highly skilled Principal Clinical Scientist to join our Imaging Physics and Radiation Protection Group at Oxford University Hospitals NHS Foundation Trust.Main DutiesSupport the delivery of Imaging Physics and Radiation Protection services to OUH and satellite trusts.Act as a Medical Physics Expert under IRMER, focusing on...

  • Principal Clinical Scientist

    6 days ago

    Oxford, Oxfordshire, United Kingdom Oxford University Hospitals Full time

    Job OverviewWe are seeking a highly skilled Principal Clinical Scientist to join our Imaging Physics and Radiation Protection Group at Oxford University Hospitals NHS Foundation Trust.Main DutiesSupport the delivery of Imaging Physics and Radiation Protection services to OUH and satellite trusts.Act as a Medical Physics Expert under IRMER, focusing on...

  • PhD Research Scientist

    2 days ago

    Oxford, Oxfordshire, United Kingdom Immunocore Full time

    Principal Scientist, Antibody PlatformVacancy No: VN469Employment Type: Full TimeLocation of role: Oxford, UKJob SummaryWe are seeking a highly skilled Principal Scientist to join our Antibody Platform team. As a key member of our Protein Engineering team, you will provide scientific and technical expertise in antibody discovery and engineering to drive our...

  • PhD Research Scientist

    2 days ago

    Oxford, Oxfordshire, United Kingdom Immunocore Full time

    Principal Scientist, Antibody PlatformVacancy No: VN469Employment Type: Full TimeLocation of role: Oxford, UKJob SummaryWe are seeking a highly skilled Principal Scientist to join our Antibody Platform team. As a key member of our Protein Engineering team, you will provide scientific and technical expertise in antibody discovery and engineering to drive our...

  • Research Scientist

    2 days ago

    Oxford, Oxfordshire, United Kingdom ZipRecruiter Full time

    Job Title: Research ScientistOxford Nanopore Technologies is a leading company in the field of nanopore sequencing, with a presence in multiple global locations. Our team is comprised of experts from various subject areas, including nanopore science, molecular biology, informatics, engineering, electronics, manufacturing, and commercialization.We are seeking...

  • Research Scientist

    2 days ago

    Oxford, Oxfordshire, United Kingdom ZipRecruiter Full time

    Job Title: Research ScientistOxford Nanopore Technologies is a leading company in the field of nanopore sequencing, with a presence in multiple global locations. Our team is comprised of experts from various subject areas, including nanopore science, molecular biology, informatics, engineering, electronics, manufacturing, and commercialization.We are seeking...

  • Senior Research Scientist

    2 weeks ago

    Oxford, Oxfordshire, United Kingdom Yellowstone Biosciences Full time

    {"Role Summary": "As a Principal Scientist at Yellowstone Biosciences, you will be a key member of our Cell Biology team, responsible for designing and troubleshooting assays to examine the binding of TCR bispecific molecules to cells, the activation of T cells, and T-cell mediated killing. You will lead programs, contribute to strategy and design of the...

  • Senior Research Scientist

    2 weeks ago

    Oxford, Oxfordshire, United Kingdom Yellowstone Biosciences Full time

    {"Role Summary": "As a Principal Scientist at Yellowstone Biosciences, you will be a key member of our Cell Biology team, responsible for designing and troubleshooting assays to examine the binding of TCR bispecific molecules to cells, the activation of T cells, and T-cell mediated killing. You will lead programs, contribute to strategy and design of the...

  • Research Scientist

    2 weeks ago

    Oxford, Oxfordshire, United Kingdom University of Oxford Full time

    Job Opportunity:We are seeking a highly skilled Research Scientist to join our Gene Medicine Group at the University of Oxford. As a Research Scientist, you will play a crucial role in developing gene therapies for a range of lung diseases.About the Role:Contribute to the production and testing of new Lentiviral vectors for therapeutic application.Support...

  • Research Scientist

    2 weeks ago

    Oxford, Oxfordshire, United Kingdom University of Oxford Full time

    Job Opportunity:We are seeking a highly skilled Research Scientist to join our Gene Medicine Group at the University of Oxford. As a Research Scientist, you will play a crucial role in developing gene therapies for a range of lung diseases.About the Role:Contribute to the production and testing of new Lentiviral vectors for therapeutic application.Support...

  • Research Scientist

    3 weeks ago

    Oxford, Oxfordshire, United Kingdom Oxford Nanopore Technologies Full time

    Job Title: Research ScientistAbout Us: Oxford Nanopore Technologies is a leading biotechnology company that specializes in the development of innovative DNA sequencing technologies.Job Summary: We are seeking a highly motivated and experienced Research Scientist to join our Nanopore Research Team. The successful candidate will be responsible for accelerating...

  • Research Scientist

    2 weeks ago

    Oxford, Oxfordshire, United Kingdom Oxford Nanopore Technologies Full time

    Job Title: Research ScientistAbout Us: Oxford Nanopore Technologies is a leading biotechnology company that specializes in the development of innovative DNA sequencing technologies.Job Summary: We are seeking a highly motivated and experienced Research Scientist to join our Nanopore Research Team. The successful candidate will be responsible for accelerating...

  • Postdoctoral Research Scientist

    7 days ago

    Oxford, Oxfordshire, United Kingdom University of Oxford Full time

    Postdoctoral Research Scientist OpportunityWe are seeking a highly motivated scientist with expertise in epigenetics, epitranscriptomics, or RNA biology to lead various projects in uncovering the role of pseudouridine and pseudouridine synthases (PUS) in cancer and exploring the potential clinical application of pseudouridine in circulating cell-free RNA for...

  • Postdoctoral Research Scientist

    6 days ago

    Oxford, Oxfordshire, United Kingdom University of Oxford Full time

    Postdoctoral Research Scientist OpportunityWe are seeking a highly motivated scientist with expertise in epigenetics, epitranscriptomics, or RNA biology to lead various projects in uncovering the role of pseudouridine and pseudouridine synthases (PUS) in cancer and exploring the potential clinical application of pseudouridine in circulating cell-free RNA for...

  • Research Scientist

    3 weeks ago

    Oxford, Oxfordshire, United Kingdom University of Oxford Full time

    Job SummaryWe are seeking a highly motivated and experienced Research Scientist to join our team at the University of Oxford. The successful candidate will have a PhD degree in a relevant topic and excellent organizational and communication skills.Key ResponsibilitiesManage and conduct independent research projectsDesign and implement research...

  • Research Scientist

    3 weeks ago

    Oxford, Oxfordshire, United Kingdom University of Oxford Full time

    Job SummaryWe are seeking a highly motivated and experienced Research Scientist to join our team at the University of Oxford. The successful candidate will have a PhD degree in a relevant topic and excellent organizational and communication skills.Key ResponsibilitiesManage and conduct independent research projectsDesign and implement research...