Computational Genomics Expert

3 weeks ago


Oxford, Oxfordshire, United Kingdom Vertex Full time

Job Title: Principal Research Scientist, Computational Genomics Lead for Oxford Research Site

Vertex is seeking a highly skilled and experienced Principal Research Scientist to lead our Computational Genomics team in Oxford. As a key member of our global research team, you will be responsible for designing and executing genomic studies to advance our drug discovery programs.

About the Role:

We are looking for a talented scientist with expertise in computational biology, bioinformatics, and genomics. Your role will involve collaborating with our Oxford Research group to design and execute genomic studies, and working closely with our global Computational Genomics team to drive the execution of genomic studies through best-practice computational analyses.

Key Responsibilities:

  1. Collaborate with Oxford disease project teams to identify key project questions or challenges that can be answered using genomics, sequencing, or bioinformatics contributions.
  2. Partner with Computational Genomics leads at our Boston and San Diego sites to prioritize global computational genomic needs and maximize impact across our global research portfolio.
  3. Serve as the accountable lead for the execution of prioritized computational genomic activities in the Oxford UK research site, and interface with Oxford leadership to provide regular progress updates.
  4. Perform advanced computational analyses of large-scale sequencing data and other biological data, through deep critical thinking, published findings, and best practices from the field.
  5. Distil complex analyses and scientific results into key take-home messages and recommendations for next steps to a broad audience.

What We're Looking For:

We are seeking a highly motivated and experienced scientist with a strong background in computational biology, bioinformatics, and genomics. You will have a proven track record in the analysis, visualization, and interpretation of large-scale human genetic data in a drug development context, and expertise in applying computational methods and bioinformatics tools to large-scale data.

Requirements:

  • Relevant education in computational biology, bioinformatics, human genetics, genomics, systems biology, bioengineering, or a related field.
  • Relevant industry or post-doctoral experience.
  • Proven track record in the analysis, visualization, and interpretation of large-scale human genetic data in a drug development context.
  • Expertise in applying computational methods and bioinformatics tools to large-scale data.
  • Proficiency with R or Python, Linux/Unix systems, and high-performance computing systems.

What We Offer:

Vertex offers a dynamic and collaborative work environment, with opportunities for professional growth and development. We are committed to diversity, equity, and inclusion, and we strive to create a workplace that is welcoming and inclusive for all employees.



  • Oxford, Oxfordshire, United Kingdom Vertex Full time

    Job Title: Computational Genomics LeadWe are seeking a highly skilled computational biologist to lead our genomics research efforts at Vertex's Oxford UK Research site. As the Computational Genomics Lead, you will be responsible for designing and executing genomic studies to advance our drug discovery programs.Key Responsibilities:Collaborate with disease...


  • Oxford, Oxfordshire, United Kingdom Vertex Pharmaceuticals Full time

    Senior Computational Genomics ScientistWe are seeking a highly skilled Senior Computational Genomics Scientist to join our team at Vertex Pharmaceuticals. As a key member of our Computational Genomics group, you will play a critical role in advancing our understanding of human disease and developing innovative therapies.Key Responsibilities:Design and...


  • Oxford, Oxfordshire, United Kingdom Vertex Full time

    Job OpportunityWe are seeking a computational biology expert to lead our genomic studies at the Oxford UK Research site. As the Computational Genomics lead, you will collaborate with the Oxford Research group to design and execute genomic studies, leveraging large-scale genomic and genetic data to advance Vertex's drug discovery programs.Key...


  • Oxford, Oxfordshire, United Kingdom University of Oxford Full time

    We are seeking a skilled professionalto fill a unique role in the Oxford Biomedical Data Science (OBDS) training programme as a Computational Biology/Data Science Trainer. This position offers a chance to play a key part in training biomedical scientists in data science and computational genomics while getting involved in computational biology research and...


  • Oxford, Oxfordshire, United Kingdom Vertex Full time

    Job OpportunityWe are seeking a highly skilled computational biology leader to join our team at Vertex's Oxford UK Research site. As the Computational Genomics lead, you will play a key role in advancing the development of transformative therapies for people with serious and life-threatening diseases.Key Responsibilities:Collaborate with Oxford disease...


  • Oxford, Oxfordshire, United Kingdom Vertex Full time

    Job OpportunityWe are seeking a computational biology leader to advance the development of transformative therapies for people with serious and life-threatening diseases. As the Computational Genomics lead at Vertex's Oxford UK Research site, you will collaborate closely with the Oxford Research group in designing and executing genomic studies to impact...


  • Oxford, Oxfordshire, United Kingdom EIT Pathogena Full time

    About EIT PathogenaEIT Pathogena is a pioneering research and development facility dedicated to revolutionizing the diagnosis and treatment of infectious diseases. Our mission is to develop Whole Genome Sequencing-based metagenomic and individual pathogen clinical tools, with the ultimate aim of establishing an 'always-on global pathogen metagenomics system'...


  • Oxford, Oxfordshire, United Kingdom Vertex Pharmaceuticals Full time

    Transformative Therapies for Serious DiseasesWe are seeking an experienced computational biology leader to leverage large-scale genomic and genetic data, driving the development of transformative therapies for people with serious and life-threatening diseases.Key ResponsibilitiesCollaborate with the Oxford Research group to design and execute genomic...


  • Oxford, Oxfordshire, United Kingdom University of Oxford Full time

    Research OpportunityWe are seeking a highly motivated and enthusiastic Front-End Developer to join the research groups of Professor, Associate Professor, and Mr. at the University of Oxford. The successful candidate will be a member of the Wellcome Genome Function Initiative and the Multi-Dimensional Viewer Team and will act as the primary point of contact...


  • Oxford, Oxfordshire, United Kingdom University of Oxford Full time

    Research Front-End Developer in Human GenomicsWe are seeking a highly motivated and enthusiastic Front-End Developer to join the research groups of Professor , Associate Professor and Mr. at the University of Oxford. The successful candidate will be a member of the Wellcome Genome Function Initiative and the Multi-Dimensional Viewer Team, and will act as the...


  • Oxford, Oxfordshire, United Kingdom EIT Pathogena Full time

    About EIT PathogenaEIT Pathogena is a pioneering research and development facility that aims to revolutionize the diagnosis and treatment of infectious diseases. Our mission is to develop Whole Genome Sequencing-based metagenomic and individual pathogen clinical tools to identify Pathogen X and provide early warning of disease epidemics.We are seeking a...


  • Oxford, Oxfordshire, United Kingdom Vertex Full time

    Job OpportunityVertex seeks a computational biology expert to join our global Computational Genomics team. As the Computational Genomics Lead, you will collaborate with the Oxford Research group to design and execute genomic studies.Key Responsibilities:Collaborate with disease project teams to identify key project questions or challenges.Partner with global...


  • Oxford, Oxfordshire, United Kingdom University of Oxford Full time

    About the RoleThe University of Oxford is seeking a highly skilled Postdoctoral Research Associate to join our team in the Department of Biology. As part of this exciting consortium, the successful applicant will utilize computational approaches to analyze gene sequences and identify engineering targets to enhance lipid content and water use efficiency in...

  • Data Engineer

    4 weeks ago


    Oxford, Oxfordshire, United Kingdom EIT Pathogena Full time

    About EIT PathogenaThe Ellison Institute of Technology (EIT) works to develop and deploy advanced technology in pursuit of solving some of humanity's most challenging and enduring problems. Guided by world-leading scientists and entrepreneurs, EIT seeks to accelerate innovation by driving scientific and technological advancements across four humane...

  • Data Engineer

    4 weeks ago


    Oxford, Oxfordshire, United Kingdom EIT Pathogena Full time

    About EIT PathogenaThe Ellison Institute of Technology (EIT) works to develop and deploy advanced technology in pursuit of solving some of humanity's most challenging and enduring problems. Guided by world-leading scientists and entrepreneurs, EIT seeks to accelerate innovation by driving scientific and technological advancements across four humane...


  • Oxford, Oxfordshire, United Kingdom University of Oxford Full time

    About the RoleThe University of Oxford is seeking a highly skilled Postdoctoral Research Associate to join our team in the Department of Biology. As part of this exciting project, you will use computational approaches to mine natural biodiversity in gene sequences to identify engineering targets to increase lipid content and enhance water use efficiency. You...


  • Oxford, Oxfordshire, United Kingdom University of Oxford Full time

    We are seeking a highly skilled Data Science Trainer to join our team at the Oxford Biomedical Data Science (OBDS) training programme. In this role, you will play a key part in training biomedical scientists in data science and computational genomics, as well as contributing to computational biology research and software development.The MRC WIMM Centre for...


  • Oxford, Oxfordshire, United Kingdom University of Oxford Full time

    About the RoleThe University of Oxford is seeking a highly skilled Postdoctoral Research Associate to join our team in the Department of Biology. As part of this exciting consortium, the successful applicant will use computational approaches to mine natural biodiversity in gene sequences to identify engineering targets to increase lipid content and enhance...


  • Oxford, Oxfordshire, United Kingdom Economicsnetwork Full time

    Project: Development of web-based human interaction methods to overcome interaction barriers with massively multidimensional genomics and machine learning data.We are seeking a skilled Front-End Developer to join the research groups of Professor Jim Hughes, Associate Professor James Davies, and Mr Stephen Taylor. You will be a member of the Wellcome Genome...


  • Oxford, Oxfordshire, United Kingdom EIT Pathogena Full time

    About EIT PathogenaEIT Pathogena is a pioneering research and development facility that leverages advanced technology to tackle humanity's most pressing challenges. Guided by world-leading scientists and entrepreneurs, we drive innovation by pushing the boundaries of scientific and technological advancements in four key areas: health and medical science,...