![Nxera Pharma](https://media.trabajo.org/img/noimg.jpg)
Hit Identification Leader
2 months ago
CK Group are working in partnership with Nxera Pharma UK Limited (formerly Sosei Heptares) to recruit a Hit Identification Leader at a Director level to lead the Hit Identification function/strategy.
Company:
Nxera Pharma is a technology powered biopharma company, in pursuit of new specialty medicines to improve the lives of patients with unmet needs globally, focused on therapeutic areas in inflammation diseases, neurology and immunology.
Their pipeline is focused on addressing major unmet needs in some of the fastest-growing areas of medicine across CNS, GI and immunology, metabolic disorders and rare diseases, and leverages the power of our unique and industry leading GPCR-targeted structure-based drug discovery “NxWave” platform to provide a sustainable source of best- or first-in-class candidates.
In Cambridge UK, Nxera have built outstanding capabilities across their platform, discovery and translational medicine teams, to advance multiple programs from pre-clinical through to early clinical development
Location:
Granta Park, Cambridge (UK).
The Role:
The successful candidate will join the Medicinal Chemistry team working closely with stakeholders to define and execute strategies to deliver high quality novel hit matter to Hit to Lead and Lead Optimization Projects. You will lead multi-disciplinary teams and manage other Medicinal Chemists.
The role will include the following responsibilities:
- Lead successful application of Nxera’s proprietary GPCR structural platform, and chemogenomic and phenotypic screening platforms, to Hit Identification.
- Enable and embed other hit finding technologies at Nxera - through expanding in-house capabilities and through partnerships.
- Contribute to the successful progression and delivery of Nxera Internal and Partnered projects.
- Interface Hit Identification with early-stage biology Target Identification/ Validation.
- Lead multi-disciplinary teams and manage other Medicinal Chemists
Your Background:
- PhD (or MSc with equivalent lab experience) in a relevant area of Chemistry.
- A proven and extensive track record of small molecule Hit Identification in an industry Drug Discovery setting.
- A history of delivering small molecule Hits which have been progressed and optimised in Drug Discovery projects.
- Proven track record of successfully leading multi-disciplinary projects in the Hit Identification or Hit to Lead phases in an industry Drug Discovery Setting.
- Experience and expertise in application of two or more distinct state of the art Hit Identification technologies/strategies.
- Experience interfacing Hit Identification and molecular tool provision with Target Identification/Validation is desirable but not essential.
Fantastic benefits on offer including:
- State-of-the-art R&D centre located in the heart of the Cambridge science cluster.
- Competitive compensation package including discretionary cash bonuses.
- 25 days annual leave in addition to public holidays.
- Employer contribution to pension.
- Private Medical Insurance and a cash plan for dental and optical reimbursement.
- Health and wellbeing benefits including a subsidised individual gym membership.
- Income protection to cover long term absences due to ill health.
- Group Death in Service equal to 4x basic annual salary.
Apply:
It is essential that applicants hold entitlement to work in the UK. Please quote job reference 105012 in all correspondence.
-
Hit Identification Leader
1 month ago
Cambridge, UK, Cambridgeshire, United Kingdom Nxera Pharma Full timeThe Role: We have an exciting Director level opportunity to join the Nxera Medicinal Chemistry team to lead the Hit Identification function/strategy.Your responsibilities:Work with key stakeholders across other disciplines in Nxera Discovery to define and execute strategies to deliver high quality novel hit matter to Hit to Lead and Lead Optimization...
-
Lead Chemist
3 weeks ago
Cambridge, Cambridgeshire, United Kingdom CK Group- Science, Clinical and Technical Full timePosition Overview: The ideal candidate will become a vital member of the Medicinal Chemistry division, collaborating closely with various stakeholders to establish and implement strategies aimed at delivering high-quality novel hit compounds for Hit to Lead and Lead Optimization initiatives. Key Responsibilities: Contribute to the effective advancement and...
-
Quality Assurance Leader
3 weeks ago
Cambridge, Cambridgeshire, United Kingdom Harris Lord Life Sciences Full timeJob OverviewQuality Assurance LeaderLocation: CambridgeSalary: £60kAre you eager to contribute significantly to the realm of digital diagnostics? We are in search of a Quality Assurance Leader who is dedicated to enhancing quality and compliance within a dynamic and innovative setting. If you possess a meticulous attention to detail and a robust background...
-
Associate Director, Research Project Leader
2 weeks ago
Cambridge, UK, Cambridgeshire, United Kingdom Bicycle Therapeutics Full timeBicycle Therapeutics is a clinical-stage biopharmaceutical company developing a novel class of medicines, referred to as Bicycle® molecules, for diseases that are underserved by existing therapeutics. Bicycle molecules are fully synthetic short peptides constrained with small molecule scaffolds to form two loops that stabilize their structural geometry....
-
Quality Assurance and Compliance Leader
3 weeks ago
Cambridge, Cambridgeshire, United Kingdom TEAM Full timePosition OverviewAre you prepared to significantly influence the realm of digital diagnostics? We are in search of a Quality Assurance & Compliance Leader who is dedicated to enhancing quality and compliance within a dynamic and innovative setting. If you possess a meticulous attention to detail and a robust understanding of ISO standards, this position...
-
Research Project Leader
3 hours ago
Cambridge, Cambridgeshire, United Kingdom Bicycle Therapeutics Full timeAbout the RoleWe are seeking an experienced Research Project Leader to join our team at Bicycle Therapeutics. As a key member of our research organization, you will provide leadership of projects spanning the drug discovery process from Lead ID to the selection of clinical candidates.Key ResponsibilitiesLead a multidisciplinary matrix team to plan and...
-
Senior Pharmacology Leader
21 hours ago
Cambridge, Cambridgeshire, United Kingdom RBW Consulting Full time**About the Role**We are seeking a highly experienced and skilled Head of Pharmacology to lead our biology team at RBW Consulting, dedicated to targeted protein degradation. Our organization is committed to developing innovative medicines for patients with unmet medical needs, leveraging our platform to discover new chemical entities.**Key...
-
Research Project Leader
21 hours ago
Cambridge, Cambridgeshire, United Kingdom Bicycle Therapeutics Full timeJob DescriptionWe are seeking an experienced Research Project Leader to join our team at Bicycle Therapeutics on a permanent, full-time basis. In this role, you will provide leadership of projects spanning the drug discovery process from Lead ID to the selection of clinical candidates.Key Responsibilities:Project Leadership: Closely work with subject matter...
-
Senior Pharmacology and Biology Leader
19 hours ago
Cambridge, Cambridgeshire, United Kingdom RBW Consulting Full timeJob OverviewRBW Consulting is seeking a highly experienced Director of Pharmacology and Biology to lead our biology team in the development of innovative medicines for patients with unmet medical needs.Key Responsibilities:Drive the progression of multiple drug discovery projects from target identification through to translational pharmacology, ensuring...
-
Computational Chemist
2 weeks ago
Cambridge, UK, Cambridgeshire, United Kingdom Bicycle Therapeutics Full timeBicycle Therapeutics is a clinical-stage biopharmaceutical company developing a novel class of medicines, referred to as Bicycle® molecules, for diseases that are underserved by existing therapeutics. Bicycle molecules are fully synthetic short peptides constrained with small molecule scaffolds to form two loops that stabilize their structural geometry....
-
Director, Research Project Manager
2 weeks ago
Cambridge, UK, Cambridgeshire, United Kingdom Bicycle Therapeutics Full timeBicycle Therapeutics is a clinical-stage biopharmaceutical company developing a novel class of medicines, referred to as Bicycle® molecules, for diseases that are underserved by existing therapeutics. Bicycle molecules are fully synthetic short peptides constrained with small molecule scaffolds to form two loops that stabilize their structural geometry....
-
Territory Sales Manager
11 hours ago
Cambridge, UK, Cambridgeshire, United Kingdom Absolute Sales & Marketing Recruitment Ltd., Full timeTERRITORY SALES MANAGER - MEDICAL DEVICES£50-70K Package – Basic + Commissions + Bonuses (NO Commission Cap), Fully Expensed, Company Car or Car Allowance, Laptop + Tablet + Phone, Holidays, Contributory PensionRequires a Hunter Attitude & Advanced Sales Skills. 3-5 years plus field sales experience, resilient, driven, and competitive. Experience selling...
-
Experienced Recruitment Consultant Cambridge
6 days ago
Cambridge, UK, Cambridgeshire, United Kingdom HAYS Full time*please note you must have a driving licence to apply for this role*Hays Recruitment Cambridge· Industry leading training throughout your career· Fast track promotionsAbout HaysAt Hays, we believe in being long-term partners with our people as well as our customers. Together, we will work for your tomorrow, and the possibilities are endless.With over 50...
-
Vice President of Clinical Trial Awareness
3 weeks ago
Cambridge, Cambridgeshire, United Kingdom Relay Therapeutics Full timeCompany: Relay Therapeutics Location: Cambridge, MA As the Senior Director of Precision Medicine Engagement and Awareness, you will spearhead the clinical trial outreach and awareness initiatives for Relay Therapeutics' breast cancer program. This pivotal role encompasses the formulation of strategic plans, collaboration with key stakeholders, and the...
-
Cambridge, Cambridgeshire, United Kingdom Relay Therapeutics Full timeJob Summary:We are seeking an experienced professional to lead our clinical trial engagement and awareness efforts for our breast cancer program. As Senior Director / Vice President of Precision Medicine Engagement and Awareness, you will develop and execute strategies to advance our clinical trials and collaborate with stakeholders to drive success.Key...
-
Vice President of Clinical Trial Awareness
3 weeks ago
Cambridge, Cambridgeshire, United Kingdom Relay Therapeutics Full timeCompany: Relay Therapeutics Location: Cambridge, MA As the Senior Director of Precision Medicine Engagement and Awareness, you will spearhead the clinical trial engagement and awareness initiatives for Relay Therapeutics' breast cancer program. This pivotal role requires the formulation of strategic plans, collaboration with key stakeholders, and the...
-
Senior Computational Chemist
3 weeks ago
Cambridge, Cambridgeshire, United Kingdom Bicycle Therapeutics Full timePosition OverviewWe are seeking a skilled computational chemist with a robust background in various methodologies, including virtual screening, molecular dynamics, and the application of machine learning (ML) models to analyze and interpret diverse project data.This role offers an opportunity to work in a highly collaborative setting, engaging with multiple...
-
Senior Computational Chemist
3 weeks ago
Cambridge, Cambridgeshire, United Kingdom Bicycle Therapeutics Full timePosition OverviewWe are seeking a skilled computational chemist proficient in a variety of methodologies, including virtual screening, molecular dynamics, and the application of machine learning (ML) models to analyze and interpret diverse project data.This role offers the opportunity to work in a collaborative atmosphere, engaging with multiple teams across...
-
Principal Security Architect
18 hours ago
Cambridge, Cambridgeshire, United Kingdom ARM Full timeJob Overview:The role will focus on helping teams adopt refreshed approaches to security requirement identification, threat modeling, coding standards, and security testing, with a focus on applying these concepts to traditional and modern infrastructure in green-field and existing deployments.This will involve taking insights from these activities to advise...
-
Senior Project Manager
2 hours ago
Cambridge, Cambridgeshire, United Kingdom Bicycle Therapeutics Full timeJob Summary:Bicycle Therapeutics is seeking a highly motivated and experienced Project Manager to provide project management across the Research organization. The successful candidate will be responsible for driving the planning and activities required for successful delivery of our portfolio of projects in close partnership with Research Project Leaders.Key...