Senior Computational Chemist

3 days ago

Cambridge, United Kingdom CV-Library Full time

Principal Computational Chemist

Cambridge

Full time and permanent

Excellent salary and benefits package

Reed Scientific are partnering with a dynamic Biotech in the Cambridge are who are seeking an experienced Computational Chemist with a passion for small molecule drug design. In this role, you will play a crucial role in the team, using your extensive expertise in computational chemistry, biomolecular structural analysis, and computational modelling techniques to drive the drug discovery programs forward.

Key Responsibilities:

Lead computational chemistry support for multiple programs
Collaborating with computational chemists, medicinal chemists, informaticians, and project teams.
Analyse and report on biomolecular and structural data using advanced modelling techniques
Develop and deliver structure- and ligand-based models (e.g., pharmacophore, docking) to advance projects
Apply a wide range of computer-aided drug design techniques
Innovate and expand the team's computational chemistry capabilities, contributing to long-term strategic vision.Qualifications and Experience:

PhD or equivalent in Computational Chemistry or related field.
Extensive experience in computer-aided drug discovery within pharma or biotech
Demonstrable knowledge of a wide range of computational chemistry approaches and their application to drug discovery
Practical experience in developing, deploying, and applying structure-based modelling techniques (e.g., docking, covalent docking, molecular dynamics simulations, FEP analysis)
Experience with computer-aided drug design techniques (e.g., compound library design, virtual screening and pharmacophore modelling)
Proven track record of innovation in computational chemistry and cheminformatics, evidenced by publications, presentations, or contributions to open-source projects
Experience using computational techniques (e.g., protein-protein docking, molecular dynamics)
Familiarity with QM/MM techniques for geometry optimization, partial charge calculation, and frontier orbital visualizationIf this sounds like the opportunity which you have been looking for, and you possess the relevant skills and experience, then please do not hesitate to apply by following the link

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