Clinical Research Laboratory Technician
2 days ago
We are seeking a highly skilled and experienced Clinical Research Laboratory Technician to join our Research and Innovation department at Nottingham University Hospitals NHS Trusts. As a key member of our team, you will play a vital role in supporting the delivery of our Cell and Therapy services, including the processing and quality control testing of cellular material.
Key Responsibilities- Perform laboratory analyses and procedures associated with the post, including reporting results and maintaining appropriate records and documentation.
- Undertake flow cytometry and support the interpretation of results.
- Undertake storage, delivery, and shipping duties of cells.
- Support quality control procedures and examine quality control results to identify poor performance.
- Undertake routine and complex laboratory-based work, including the pre-analytical processing of clinical trial specimens and samples for analysis using various technologies.
- Perform clerical tasks, including monitoring and querying sample processing requests made by the clinical team, completing sample tracking logs, equipment maintenance logs, and other documentations appropriate for the role.
- Accurately follow or design protocols to ensure the smooth running of the facility and the accurate processing of study samples.
- Collect, catalogue, and store human tissue, blood, and urine samples from within the R&I department, Nottingham University Hospitals, or external sites. Manage sample storage facilities and maintain collections, including monitoring freezers.
- Organise sample retrieval from external sites, which may require flexibility in working hours.
- Culture of epithelial and smooth muscle cells from human lung biopsies.
- Process human sputum samples, including differential cell count.
- Accurately record sample transfers both in and out of R&I laboratories.
- Isolate stored samples for transfer to or from the R&I laboratories, arranging couriers and ensuring samples are packed appropriately.
- Observe all GLP, GCP, HSE, and HTA regulations, maintaining records to comply with the Human Tissue Act, and adhering to Trust policy and procedures.
- Be responsible for the upkeep of the lab areas and equipment, maintaining laboratory stock levels of chemicals and consumables, and ensuring adequate equipment maintenance.
- Maintain and clean laboratory equipment, maintaining a high standard of housekeeping within the laboratory.
- Perform any other duties appropriate to the role and level.
- Assist in the induction and training of new laboratory staff, providing mentorship and support within the clinical team.
- Contribute to the development of clinical and research policies and Standard Operating Procedures.
- Act as a resource for colleagues in relation to clinical studies.
- Attend relevant training and gain experience from other laboratories, which may involve travel.
- Keep appropriate staff informed of the progress of clinical studies.
- Maintain an up-to-date knowledge of relevant research-related articles, particularly those related to clinical studies.
- Continue your own professional development according to appropriate regulatory guidance, keeping updated with current practice.
- Assist with training of placement students in relevant scientific techniques.
- Attend national meetings/conferences in relation to clinical studies as appropriate and agreed with the R&I Laboratory Manager.
Physical Skills
Essential
- Manual dexterity required to perform tasks.
- Physically capable of carrying out laboratory tasks and capable of intense periods of concentration.
Commitment to Trust Values and Behaviours
Essential
- Must be able to demonstrate behaviours consistent with the Trust's behavioural standards.
Training & Qualifications
Essential
- BSc in a biological or biomedical subject or attained or working towards NVQ level 3 in Clinical Laboratory Support or equivalent qualification or equivalent experience.
- Extensive experience as a scientist/technician working in an academic or healthcare/clinical laboratory within Haematology, Blood transfusion, and transplantation or other closely related fields.
- Knowledge and experience of Good Laboratory practice and research governance.
- Demonstrates a commitment to continuing education and training.
- Can maintain confidentiality and act professionally.
Desirable
- MSc in a biological or biomedical subject.
- IBMS membership.
- Demonstrates a knowledge and awareness of instrumentation, method development, and new technologies.
Experience
Essential
- Demonstrable knowledge/experience in flow cytometry and Tissue Culture work.
- Relevant laboratory experience of at least 12 months.
- Knowledge of Equal Opportunities, Human Tissue Act, and Data Protection/Confidentiality.
- Knowledge of GCLP and Health & Safety legislations related to the Laboratory.
- Conscientious and meticulous, demonstrates ability to organise their own work effectively.
- Keyboard skills and computer literacy.
Desirable
- HCPC Registration.
- Experience of laboratory management and quality control.
- Experience of laboratory stock control.
- Training junior staff.
- Has a genuine interest in the future of Stem Cell and Cell Therapy work.
- Experience of audit.
Communication and Relationship Skills
Essential
- Good interpersonal skills. Able to communicate concisely, effectively, and clearly.
- Able to work well in a team and as an individual.
- Can maintain confidentiality and act professionally.
Desirable
- Demonstrates a range of IT skills.
Analytical and Judgement Skills
Essential
- Able to make judgements regarding complex facts or situations that require analysis, interpretation, and comparison of a range of options. Trouble shooting and resolving issues such as mismatched samples, QA assessments, and technical failures.
Desirable
- Experience of troubleshooting in a laboratory setting.
Planning and Organisation Skills
Essential
- Able to plan own work activities and those of supervised staff.
- Able to meet agreed targets on an ongoing basis.
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